Marilena Briglia
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View article: The Skin Photophores of Chauliodus sloani Bloch & Schneider, 1801 (Pisces: Stomiidae): A Morphological, Ultrastructural and Immunohistochemical Study
The Skin Photophores of Chauliodus sloani Bloch & Schneider, 1801 (Pisces: Stomiidae): A Morphological, Ultrastructural and Immunohistochemical Study Open
This work provides a contribution to the understanding of the structure of the photophores in the mesopelagic fish Chauliodus sloani (family Stomiidae), which occasionally are stranded along the coasts of the Strait of Messina (Central Med…
View article: Medulloblastoma: Molecular Targets and Innovative Theranostic Approaches
Medulloblastoma: Molecular Targets and Innovative Theranostic Approaches Open
Background/Objectives: Medulloblastoma is a rare tumor that represents almost two-thirds of all embryonal pediatric brain tumor cases. Current treatments, including surgery, radiation, and chemotherapy, are often associated with adverse ef…
View article: Different light/dark condition modulation of the daily rhythm of insulin and glucagon in dogs
Different light/dark condition modulation of the daily rhythm of insulin and glucagon in dogs Open
Considering the importance of glucose homeostasis and knowing that the alteration of its regulation is the cause of many dogs’ pathologies, the present study aimed to investigate insulin, glucagon, and glucose daily rhythmicity in dogs sub…
View article: Circadian Oscillation of Leukocyte Subpopulations and Inflammatory Cytokines over a 24-H Period in Horses
Circadian Oscillation of Leukocyte Subpopulations and Inflammatory Cytokines over a 24-H Period in Horses Open
The objective of the present study was to investigate the influence of daily rhythms on the immune and inflammatory systems in horses, considering white blood cell count (WBCs), leukocyte subpopulations (neutrophils, basophils, eosinophils…
View article: Innovation in Osteogenesis Activation: Role of Marine-Derived Materials in Bone Regeneration
Innovation in Osteogenesis Activation: Role of Marine-Derived Materials in Bone Regeneration Open
Marine-derived biomaterials are emerging as promising candidates for tissue regeneration due to their sustainability, biocompatibility, bioactivity, and unique chemical structure. This review provides an overview of different marine-derive…
View article: Investigating the plasma electrophoretic protein profile of kids and lambs during the neonatal period: An overview of their immuno-inflammatory status
Investigating the plasma electrophoretic protein profile of kids and lambs during the neonatal period: An overview of their immuno-inflammatory status Open
View article: The Role of Pericytes in Inner Ear Disorders: A Comprehensive Review
The Role of Pericytes in Inner Ear Disorders: A Comprehensive Review Open
Inner ear disorders, including sensorineural hearing loss, Meniere’s disease, and vestibular neuritis, are prevalent conditions that significantly impact the quality of life. Despite their high incidence, the underlying pathophysiology of …
View article: Diet and Nutrients in Rare Neurological Disorders: Biological, Biochemical, and Pathophysiological Evidence
Diet and Nutrients in Rare Neurological Disorders: Biological, Biochemical, and Pathophysiological Evidence Open
Background/Objectives: Rare diseases are a wide and heterogeneous group of multisystem life-threatening or chronically debilitating clinical conditions with reduced life expectancy and a relevant mortality rate in childhood. Some of these …
View article: Neurotrophins and Trk Neurotrophin Receptors in the Retina of Adult Killifish (Nothobranchius guentheri)
Neurotrophins and Trk Neurotrophin Receptors in the Retina of Adult Killifish (Nothobranchius guentheri) Open
Specific subpopulations of neurons in nerve and sensory systems must be developed and maintained, and this is accomplished in significant part by neurotrophins (NTs) and the signaling receptors on which they act, called tyrosine protein ki…
View article: The odd couple: Caffeine and microplastics. Morphological and physiological changes in <i>Mytilus galloprovincialis</i>
The odd couple: Caffeine and microplastics. Morphological and physiological changes in <i>Mytilus galloprovincialis</i> Open
In recent years, the presence of pharmaceuticals and microplastics (MPs) in aquatic ecosystems has raised concerns about their environmental impact. This study explores the combined effects of caffeine, a common pharmaceutical pollutant, a…
View article: Skeletal Morphogenesis and Anomalies in Gilthead Seabream: A Comprehensive Review
Skeletal Morphogenesis and Anomalies in Gilthead Seabream: A Comprehensive Review Open
The gilthead seabream, one of the most important species in Mediterranean aquaculture, with an increasing status of exploitation in terms of production volume and aquafarming technologies, has become an important research topic over the ye…
View article: Vimentin Localization in the Zebrafish Oral Cavity: A Potential Role in Taste Buds Regeneration
Vimentin Localization in the Zebrafish Oral Cavity: A Potential Role in Taste Buds Regeneration Open
The morphology of the oral cavity of fish is related to their feeding habits. In this context, taste buds are studied for their ability to catch chemical stimuli and their cell renewal capacity. Vimentin RV202 is a protein employed as a ma…
View article: Review on Gilthead Seabream (Sparus aurata) Aquaculture: Life Cycle, Growth, Aquaculture Practices and Challenges
Review on Gilthead Seabream (Sparus aurata) Aquaculture: Life Cycle, Growth, Aquaculture Practices and Challenges Open
Over the years, the gilthead seabream (Sparus aurata), a prominent species in Mediterranean aquaculture with an increasing production volume and aquafarming technologies, has become an important research focus. The accumulation of knowledg…
View article: Localization of Calretinin, Parvalbumin, and S100 Protein in Nothobranchius guentheri Retina: A Suitable Model for the Retina Aging
Localization of Calretinin, Parvalbumin, and S100 Protein in Nothobranchius guentheri Retina: A Suitable Model for the Retina Aging Open
Calcium-binding proteins (CaBPs) are members of a heterogeneous family of proteins able to buffer intracellular Ca2+ ion concentration. CaBPs are expressed in the central and peripheral nervous system, including a subpopulation of retinal …
View article: Nothobranchius as a model for anorexia of aging research: an evolutionary, anatomical, histological, immunohistochemical, and molecular study
Nothobranchius as a model for anorexia of aging research: an evolutionary, anatomical, histological, immunohistochemical, and molecular study Open
Our study introduces Nothobranchius rachovii as a model for anorexia of aging, giving the first bases on the gastrointestinal tract morphology and cck expression pattern. Future studies on young and elderly Notobranchius can divulge the co…
View article: Potential Neuroprotective Role of Calretinin-N18 and Calbindin-D28k in the Retina of Adult Zebrafish Exposed to Different Wavelength Lights
Potential Neuroprotective Role of Calretinin-N18 and Calbindin-D28k in the Retina of Adult Zebrafish Exposed to Different Wavelength Lights Open
The incidence rates of light-induced retinopathies have increased significantly in the last decades because of continuous exposure to light from different electronic devices. Recent studies showed that exposure to blue light had been relat…
View article: The Alimentary Tract of African Bony-Tongue, Heterotis niloticus (Cuvier, 1829): Morphology Study
The Alimentary Tract of African Bony-Tongue, Heterotis niloticus (Cuvier, 1829): Morphology Study Open
A morphological study of the alimentary tract, from the oropharyngeal cavity to the rectum, including the attached glands, of African bony-tongue, Heterotis niloticus (Cuvier, 1829) was carried out by gross anatomy, and light microscope an…
View article: Zebrafish and Flavonoids: Adjuvants against Obesity
Zebrafish and Flavonoids: Adjuvants against Obesity Open
Obesity is a pathological condition, defined as an excessive accumulation of fat, primarily caused by an energy imbalance. The storage of excess energy in the form of triglycerides within the adipocyte leads to lipotoxicity and promotes th…
View article: Nocodazole Induced Suicidal Death of Human Erythrocytes
Nocodazole Induced Suicidal Death of Human Erythrocytes Open
Background: The microtubule assembly inhibitor nocodazole has been shown to trigger caspase-independent mitotic death and caspase dependent apoptosis. Similar to apoptosis of nucleated cells, erythrocytes may undergo eryptosis, the suicida…
View article: Induction of Suicidal Erythrocyte Death by Cantharidin
Induction of Suicidal Erythrocyte Death by Cantharidin Open
The natural phosphoprotein phosphatase inhibitor cantharidin, primarily used for topical treatment of warts, has later been shown to trigger tumor cell apoptosis and is thus considered for the treatment of malignancy. Similar to apoptosis …
View article: Triggering of Suicidal Erythrocyte Death by Ruxolitinib
Triggering of Suicidal Erythrocyte Death by Ruxolitinib Open
Background/Aims: The JAK1/JAK2 tyrosine kinase inhibitor ruxolitinib is widely used for the treatment of myeloproliferative neoplasm-associated myelofibrosis and other malignancies. Most important side effects include anemia. A common caus…
View article: Triggering of Suicidal Erythrocyte Death by Zosuquidar
Triggering of Suicidal Erythrocyte Death by Zosuquidar Open
Background: The P-glycoprotein inhibitor zosuquidar (LY335979) is clinically used to augment the effect of cytostatic drugs on suicidal tumor cell death or apoptosis. The present study explored whether the substance is cytotoxic to erythro…
View article: Oxaliplatin Induced Suicidal Death of Human Erythrocytes
Oxaliplatin Induced Suicidal Death of Human Erythrocytes Open
Background/Aims: The alkylating drug oxaliplatin is widely used for chemotherapy of malignancy. Oxaliplatin is effective by inducing both, necrosis and apoptosis. Similar to necrosis or apoptosis of nucleated cells, erythrocytes may enter …
View article: Stimulation of Suicidal Erythrocyte Death by Garcinol
Stimulation of Suicidal Erythrocyte Death by Garcinol Open
Background/Aims: The benzophenone garcinol from dried fruit rind of Garcinia indica counteracts malignancy, an effect at least in part due to stimulation of apoptosis. The proapototic effect of garcinol is attributed in part to inhibition …
View article: Edelfosine Induced Suicidal Death of Human Erythrocytes
Edelfosine Induced Suicidal Death of Human Erythrocytes Open
Background/Aims: The anti-inflammatory, anti-autoimmune, antiparasitic, and anti-viral ether phospholipid edelfosine (1-O-octadecyl-2-O-methylglycero-3-phosphocholine) stimulates apoptosis of tumor cells and is thus considered for the trea…
View article: Fucoxanthin Induced Suicidal Death of Human Erythrocytes
Fucoxanthin Induced Suicidal Death of Human Erythrocytes Open
Background/Aims: Fucoxanthin, a carotenoid isolated from brown seaweeds, induces suicidal death or apoptosis of tumor cells and is thus considered for the treatment or prevention of malignancy. In analogy to apoptosis of nucleated cell, er…