Marina Farrel Côrtes
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View article: Impact of FilmArray Gastrointestinal Panel Compared to Standard of Care Diagnostic Tests in Clinical Practice of Acute Gastroenteritis in a Resource Limited Region
Impact of FilmArray Gastrointestinal Panel Compared to Standard of Care Diagnostic Tests in Clinical Practice of Acute Gastroenteritis in a Resource Limited Region Open
Background/Objectives: Gastroenteritis remains a major global health concern, particularly in resource-limited regions, where rapid and accurate diagnosis is crucial for effective patient management. Syndromic multiplex PCR panels, such as…
View article: Multidrug-resistant Klebsiella pneumoniae ST70 harboring blaNDM in a migratory Penguin
Multidrug-resistant Klebsiella pneumoniae ST70 harboring blaNDM in a migratory Penguin Open
View article: Metagenomic detection of central nervous system infections missedby conventional testing
Metagenomic detection of central nervous system infections missedby conventional testing Open
Community-acquired infectious meningoencephalitis is associated with high rates of mortality and morbidity, compounded by limited access to diagnostic resources. The current study assessed acute central nervous system (CNS) infections in p…
View article: Transcriptomic insights into early mechanisms underlying post-chikungunya chronic inflammatory joint disease
Transcriptomic insights into early mechanisms underlying post-chikungunya chronic inflammatory joint disease Open
View article: Characterization of aminoglycoside resistance in multidrug-resistant Klebsiella pneumoniae isolates
Characterization of aminoglycoside resistance in multidrug-resistant Klebsiella pneumoniae isolates Open
Multidrug-resistant (MDR) Klebsiella pneumoniae, particularly the lineages resistant to carbapenems and aminoglycosides, is an escalating global public health threat across human, animal, and environmental reservoirs. We examined phenotypi…
View article: Impact of Exogenous Lactiplantibacillus plantarum on the Gut Microbiome of Hematopoietic Stem Cell Transplantation Patients Colonized by Multidrug-Resistant Bacteria: An Observational Study
Impact of Exogenous Lactiplantibacillus plantarum on the Gut Microbiome of Hematopoietic Stem Cell Transplantation Patients Colonized by Multidrug-Resistant Bacteria: An Observational Study Open
Background: Lactiplantibacillus plantarum can inhibit the growth of multidrug-resistant organisms (MDROs) and modulate the gut microbiome. However, data on hematopoietic stem cell transplantation (HSCT) are scarce. Aim: In an observational…
View article: OR-46 - ASSOCIAÇÃO ENTRE GENES DE VIRULÊNCIA DE MYCOBACTERIUM TUBERCULOSIS E MARCADORES CLÍNICOS DE GRAVIDADE
OR-46 - ASSOCIAÇÃO ENTRE GENES DE VIRULÊNCIA DE MYCOBACTERIUM TUBERCULOSIS E MARCADORES CLÍNICOS DE GRAVIDADE Open
Introdução: A gravidade da tuberculose depende da interação entre a resposta imune do hospedeiro e a virulência do Mycobacterium tuberculosis (Mtb). Pouco se conhece sobre a associação entre a caracterização genotípica e os aspectos clínic…
View article: Colonization by Extended-Spectrum β-Lactamase-Producing Enterobacterales and Bacteremia in Hematopoietic Stem Cell Transplant Recipients
Colonization by Extended-Spectrum β-Lactamase-Producing Enterobacterales and Bacteremia in Hematopoietic Stem Cell Transplant Recipients Open
Background: Assessing the risk of multidrug-resistant colonization and infections is pivotal for optimizing empirical therapy in hematopoietic stem cell transplants (HSCTs). Limited data exist on extended-spectrum β-lactamase-producing Ent…
View article: COVID-19 in hematopoietic stem cell transplant recipients during three years of the pandemic: a multicenter study in Brazil
COVID-19 in hematopoietic stem cell transplant recipients during three years of the pandemic: a multicenter study in Brazil Open
Hematopoietic stem cell transplant (HSCT) recipients are at -increased risk for severe COVID-19. The aim of this study was to evaluate the burden of COVID-19 in a cohort of HSCT recipients. This retrospective study evaluated a cohort of ad…
View article: In Vitro Activity of Amikacin Combined with Meropenem, Colistin and Ceftazidime/Avibactam Against Genetically Distinct Multidrug-Resistant K. Pneumoniae, a. Baumannii and S. Marcescens Isolates Using Three Methods
In Vitro Activity of Amikacin Combined with Meropenem, Colistin and Ceftazidime/Avibactam Against Genetically Distinct Multidrug-Resistant K. Pneumoniae, a. Baumannii and S. Marcescens Isolates Using Three Methods Open
View article: Case Report: In Situ and Systemic Immune Response to Mucosal Leishmaniasis in an HIV-Infected Patient
Case Report: In Situ and Systemic Immune Response to Mucosal Leishmaniasis in an HIV-Infected Patient Open
In situ and systemic evaluations of the immune responses of HIV-infected patients to mucosal leishmaniasis have been poorly described. We describe a recently diagnosed HIV-infected patient with mucosal leishmaniasis who was characterized b…
View article: Title Impact of Exogenous<em> Lactobacillus plantarum</em> on the Gut Microbiome of Hematopoietic Stem Cell Transplantation Patients Colonized by Multi-Drug Resistant Bacteria
Title Impact of Exogenous<em> Lactobacillus plantarum</em> on the Gut Microbiome of Hematopoietic Stem Cell Transplantation Patients Colonized by Multi-Drug Resistant Bacteria Open
Gut colonization by multidrug resistant organisms(MDROs) is a risk factor for bloodstream infections(BSI) in the early phase of Hematopoietic Stem Cell Transplantation(HSCT). We evaluated, in an exploratory study, the impact of Lactobacill…
View article: Investigation of antimicrobial susceptibility and genetic diversity among Staphylococcus pseudintermedius isolated from dogs in Rio de Janeiro
Investigation of antimicrobial susceptibility and genetic diversity among Staphylococcus pseudintermedius isolated from dogs in Rio de Janeiro Open
Staphylococcus pseudintermedius is an opportunistic pathogen causing a variety of infections that are difficult to treat, especially because of the development of antimicrobial resistance. It has a clonal distribution around the world. To …
View article: Epidemiologic case investigation on the zoonotic transmission of Methicillin-resistant Staphylococcus pseudintermedius among dogs and their owners
Epidemiologic case investigation on the zoonotic transmission of Methicillin-resistant Staphylococcus pseudintermedius among dogs and their owners Open
Dogs often carry methicillin-resistant Staphylococci asymptomatically. These bacteria are frequently linked to conditions such as canine pyoderma and otitis. Close interaction between dogs and humans can facilitate the exchange of resistan…
View article: DESENVOLVIMENTO DE APTÂMEROS DE DNA CONTRA ACINETOBACTER BAUMANII MULTIDROGAS RESISTENTES
DESENVOLVIMENTO DE APTÂMEROS DE DNA CONTRA ACINETOBACTER BAUMANII MULTIDROGAS RESISTENTES Open
Introdução/Objetivo: As infecções causadas por agentes multirresistentes são um problema de saúde mundial, com altas taxas de mortalidade. A identificação rápida dessas infecções é essencial, devido à sua natureza contagiosa, dificuldade d…
View article: PERFIL DE PROTEÍNA MALDI-TOF MS DE AMOSTRAS DE URINA COMO FATOR PREDITIVO DE GRAVIDADE DA COVID-19 USANDO MACHINE LEARNING
PERFIL DE PROTEÍNA MALDI-TOF MS DE AMOSTRAS DE URINA COMO FATOR PREDITIVO DE GRAVIDADE DA COVID-19 USANDO MACHINE LEARNING Open
Introdução/Objetivos: O prognóstico da COVID-19 é uma etapa essencial para aumentar a sobrevida do paciente e desempenha um papel importante na alocação de recursos de saúde. A detecção precoce da COVID-19 grave requer técnicas não invasiv…
View article: ALTERAÇÕES TRANSCRICIONAIS PRECOCEMENTE ENVOLVIDAS NA PROGRESSÃO DE PACIENTES PARA DOENÇA ARTICULAR CRÔNICA PÓS-CHIKUNGUNYA
ALTERAÇÕES TRANSCRICIONAIS PRECOCEMENTE ENVOLVIDAS NA PROGRESSÃO DE PACIENTES PARA DOENÇA ARTICULAR CRÔNICA PÓS-CHIKUNGUNYA Open
Introdução/Objetivo: Infecções pelo vírus Chikungunya (CHIKV) podem frequentemente resultar no desenvolvimento de Doença Articular Inflamatória Crônica pós-Chikungunya (pCHIKV-CIJD). Essa condição gera impactos na qualidade de vida dos pac…
View article: PREDITORES DE PROTEÇÃO CONTRA COVID-19 EM PROFISSIONAIS DE SAÚDE VACINADOS DURANTE 5 ONDAS CAUSADAS POR VARIANTES DE PREOCUPAÇÃO DO SARS-COV-2 EM SÃO PAULO, BRASIL
PREDITORES DE PROTEÇÃO CONTRA COVID-19 EM PROFISSIONAIS DE SAÚDE VACINADOS DURANTE 5 ONDAS CAUSADAS POR VARIANTES DE PREOCUPAÇÃO DO SARS-COV-2 EM SÃO PAULO, BRASIL Open
Introdução: Os fatores de proteção contra as diferentes variantes do SARS-CoV-2 não estão completamente elucidados. Nosso objetivo foi avaliar o efeito das doses vacinais de reforço e infecções prévias no risco de COVID-19 em profissionais…
View article: PERFIS GENOTÍPICOS DE VIRULÊNCIA RELACIONADOS A INVASIVIDADE DAS CEPAS DE NEISSERIA GONORRHOEAE EM PACIENTES DO HOSPITAL DAS CLÍNICAS DA FACULDADE DE MEDICINA DA UNIVERSIDADE DE SÃO PAULO
PERFIS GENOTÍPICOS DE VIRULÊNCIA RELACIONADOS A INVASIVIDADE DAS CEPAS DE NEISSERIA GONORRHOEAE EM PACIENTES DO HOSPITAL DAS CLÍNICAS DA FACULDADE DE MEDICINA DA UNIVERSIDADE DE SÃO PAULO Open
Introdução: As infecções causadas por Neisseria gonorrhoeae (Ng) ainda representam um desafio no enfrentamento das infecções sexualmente transmissíveis (ISTs) no mundo. Dentro do espectro de doenças causadas pela Ng, a doença gonocócica in…
View article: CARACTERIZAÇÃO FENOTÍPICA E GENOTÍPICA DE CEPAS DE KLEBSIELLA PNEUMONIAE RESISTENTE AOS AMINOGLICOSÍDEOS: UMA ABORDAGEM INTEGRADA "ONE HEALTH"
CARACTERIZAÇÃO FENOTÍPICA E GENOTÍPICA DE CEPAS DE KLEBSIELLA PNEUMONIAE RESISTENTE AOS AMINOGLICOSÍDEOS: UMA ABORDAGEM INTEGRADA "ONE HEALTH" Open
A disseminação de Klebsiella pneumoniae multirresistente (MDR), representa um desafio para a saúde pública. No entanto, pouco se sabe sobre a disseminação em animais, alimentos e ambiente, e sua potencial transmissão para humanos. Neste es…
View article: Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated with Haemophilus influenzae Meningitis in a Newborn
Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated with Haemophilus influenzae Meningitis in a Newborn Open
Parvovirus B19 infection is associated with a wide range of clinical manifestations, from asymptomatic to severe neurological disorders. Its major clinical symptoms, fever and rash, are common to multiple viruses, and laboratory tests to d…
View article: Performance Evaluation of VIDAS® Diagnostic Assays Detecting Anti-Chikungunya Virus IgM and IgG Antibodies: An International Study
Performance Evaluation of VIDAS® Diagnostic Assays Detecting Anti-Chikungunya Virus IgM and IgG Antibodies: An International Study Open
Chikungunya (CHIK) is a debilitating mosquito-borne disease with an epidemiology and early clinical symptoms similar to those of other arboviruses-triggered diseases such as dengue or Zika. Accurate and rapid diagnosis of CHIK virus (CHIKV…
View article: Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated With Haemophilus influenzae Meningitis in a Newborn
Encephalopathy Caused by Human Parvovirus B19 Genotype 1 Associated With Haemophilus influenzae Meningitis in a Newborn Open
Parvovirus B19 infection is associated with a wide range of clinical manifestations, from asymp-tomatic to severe neurological disorders. Its major clinical symptoms, fever and rash, are com-mon to multiple viruses, and laboratory tests to…
View article: Clinical markers of post-Chikungunya chronic inflammatory joint disease: A Brazilian cohort
Clinical markers of post-Chikungunya chronic inflammatory joint disease: A Brazilian cohort Open
Background Chikungunya-fever (CHIKF) remains a public health major issue. It is clinically divided into three phases: acute, post-acute and chronic. Chronic cases correspond to 25–40% individuals and, though most of them are characterized …
View article: Long COVID in a Multicentric Brazilian Cohort: Acute Phase Symptom Burden and Second Booster Dose Vaccination Effects
Long COVID in a Multicentric Brazilian Cohort: Acute Phase Symptom Burden and Second Booster Dose Vaccination Effects Open
View article: Virulomic Analysis of Multidrug-Resistant Klebsiella pneumoniae Isolates and Experimental Virulence Model Using Danio rerio (Zebrafish)
Virulomic Analysis of Multidrug-Resistant Klebsiella pneumoniae Isolates and Experimental Virulence Model Using Danio rerio (Zebrafish) Open
This study evaluates a possible correlation between multidrug-resistant Klebsiella pneumoniae strains and virulence markers in a Danio rerio (zebrafish) model. Whole-genome sequencing (WGS) was performed on 46 strains from three Brazilian …
View article: Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Shedding and Predictors of Viral Culture Positivity on Vaccinated Healthcare Workers With Mild Coronavirus Disease 2019
Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Shedding and Predictors of Viral Culture Positivity on Vaccinated Healthcare Workers With Mild Coronavirus Disease 2019 Open
In this prospective cohort of 30 vaccinated healthcare workers with mild Omicron variant infection, we evaluated viral culture, rapid antigen test (RAT), and real-time reverse-transcription polymerase chain reaction (RT-PCR) of respiratory…
View article: CARACTERIZAÇÃO DA INFECTIVIDADE DA VARIANTE ÔMICRON E PREDITORES DE POSITIVIDADE DE CULTURA VIRAL EM PROFISSIONAIS DE SAÚDE COM COVID-19 LEVE
CARACTERIZAÇÃO DA INFECTIVIDADE DA VARIANTE ÔMICRON E PREDITORES DE POSITIVIDADE DE CULTURA VIRAL EM PROFISSIONAIS DE SAÚDE COM COVID-19 LEVE Open
INTRODUÇÃO: A variante Ômicron do vírus SARS-CoV-2 (B.1.1.529) foi designada uma variante preocupante (VOC) devido à alta transmissibilidade e capacidade de escapar da imunidade natural e induzida por vacina. OBJETIVO: Caracterizar a duraç…
View article: DESENVOLVIMENTO DE APTÂMEROS CONTRA KLEBSIELLA PNEUMONIAE
DESENVOLVIMENTO DE APTÂMEROS CONTRA KLEBSIELLA PNEUMONIAE Open
Introdução: Bactérias gram-negativas são importantes agentes de Infecções Relacionadas a Assistência à Saúde (IRAS), sendo a Klebsiella pneumoniae responsável por 16,9% das infecções de corrente sanguínea no Brasil. É um agente oportunista…
View article: ESTUDO DE SINERGISMO IN VITRO PARA AVALIAÇÃO DA ATIVIDADE ANTIMICROBIANA DOS AMINOGLICOSÍDEOS EM COMBINAÇÃO COM OUTRAS DROGAS EM BACTÉRIAS GRAM-NEGATIVAS MULTIRRESISTENTES
ESTUDO DE SINERGISMO IN VITRO PARA AVALIAÇÃO DA ATIVIDADE ANTIMICROBIANA DOS AMINOGLICOSÍDEOS EM COMBINAÇÃO COM OUTRAS DROGAS EM BACTÉRIAS GRAM-NEGATIVAS MULTIRRESISTENTES Open