Marine Barthez
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View article: <scp>SIRT2</scp> and <scp>NAD</scp><sup>+</sup> Boosting Broadly Suppress Aging‐Associated Inflammation
<span>SIRT2</span> and <span>NAD</span><sup>+</sup> Boosting Broadly Suppress Aging‐Associated Inflammation Open
Aging leads to chronic inflammation that is linked to aging‐associated conditions and diseases. Multiple immune pathways become activated during aging, posing a challenge to effectively reduce aging‐associated inflammation. SIRT2, an NAD +…
View article: SIRT2 suppresses aging-associated cGAS activation and protects aged mice from severe COVID-19
SIRT2 suppresses aging-associated cGAS activation and protects aged mice from severe COVID-19 Open
Aging-associated vulnerability to coronavirus disease 2019 (COVID-19) remains poorly understood. Here, we show that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected aged mice lacking SIRT2, a cytosolic NAD+-…
View article: M1BP is an essential transcriptional activator of oxidative metabolism during Drosophila development
M1BP is an essential transcriptional activator of oxidative metabolism during Drosophila development Open
View article: The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease
The hepatic integrated stress response suppresses the somatotroph axis to control liver damage in nonalcoholic fatty liver disease Open
Nonalcoholic fatty liver disease (NAFLD) can be ameliorated by calorie restriction, which leads to the suppressed somatotroph axis. Paradoxically, the suppressed somatotroph axis is associated with patients with NAFLD and is correlated wit…
View article: Stem Cell Metabolism and Diet
Stem Cell Metabolism and Diet Open
View article: Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation
Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation Open
Autophagy is an essential cellular process that maintains homeostasis by recycling damaged organelles and nutrients during development and cellular stress. ZKSCAN3 is the sole identified master transcriptional repressor of autophagy in hum…
View article: Human ZKSCAN3 and <i>Drosophila</i> M1BP are functionally homologous transcription factors in autophagy regulation
Human ZKSCAN3 and <i>Drosophila</i> M1BP are functionally homologous transcription factors in autophagy regulation Open
Autophagy is an essential cellular process that maintains homeostasis by recycling damaged organelles and nutrients during development and cellular stress. ZKSCAN3 is the sole identified master transcriptional repressor of autophagy in hum…
View article: The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1<scp>BP</scp> to regulate gene transcription
The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1<span>BP</span> to regulate gene transcription Open