Marine L. Andersson
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View article: Increased mortality in dementia patients using inhaled anticholinergics: A nationwide register study from the Swedish registry on dementia/cognitive disorders, SveDem
Increased mortality in dementia patients using inhaled anticholinergics: A nationwide register study from the Swedish registry on dementia/cognitive disorders, SveDem Open
Background Patients with chronic obstructive pulmonary disease (COPD) face increased risks of cognitive impairment and mortality compared with the general population. Inhaled anticholinergics (LAMA/SAMA) are central in COPD treatment. The …
View article: Drug‐Induced <scp>QT</scp> Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes
Drug‐Induced <span>QT</span> Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes Open
Potential adverse drug events can be signaled in Clinical Decision Support Systems (CDSSs). This study validated a Swedish CDSS (Janusmed Risk Profile) by investigating associations between calculated risk classifications of drugs with QT‐…
View article: Higher socioeconomic status is associated with dispensation of monoclonal antibodies against calcitonin gene-related peptide in migraine: A nested case-control study
Higher socioeconomic status is associated with dispensation of monoclonal antibodies against calcitonin gene-related peptide in migraine: A nested case-control study Open
Background Higher socioeconomic status (SES) among people with migraine has been associated with an increased use of triptans, but it is undetermined whether high SES is also associated with dispensation of monoclonal antibodies against ca…
View article: Potential Adverse Drug Events Identified with Decision Support Algorithms from Janusmed Risk Profile—A Retrospective Population-Based Study in a Swedish Region
Potential Adverse Drug Events Identified with Decision Support Algorithms from Janusmed Risk Profile—A Retrospective Population-Based Study in a Swedish Region Open
Adverse drug events (ADEs) occur frequently and are a common cause of suffering, hospitalizations, or death, and can be caused by harmful combinations of medications. One method used to prevent ADEs is by using clinical decision support sy…
View article: Drug–Drug Interactions in Patients with Acute Respiratory Distress Syndrome
Drug–Drug Interactions in Patients with Acute Respiratory Distress Syndrome Open
Acute respiratory distress syndrome (ARDS) is a potential life-threatening, heterogenous, inflammatory lung disease. There are no data available on potential drug–drug interactions (pDDIs) in critically ill patients with ARDS. This study a…
View article: P1283: CIRCULATING IMMUNE CELLS IN CLASSICAL HODGKIN LYMPHOMA IN RELATION TO TUMOR BURDEN AND TREATMENT
P1283: CIRCULATING IMMUNE CELLS IN CLASSICAL HODGKIN LYMPHOMA IN RELATION TO TUMOR BURDEN AND TREATMENT Open
Background: Classical Hodgkin lymphoma (cHL) has a peculiar histology with pathognomonic Hodgkin and Reed-Sternberg (HRS) cells representing only a small fraction of the tumor mass. HRS orchestrate a lymphocyte-dominated tumor microenviron…
View article: Patients’ Use and Perceptions of a Drug-Drug Interaction Database: A Survey of Janusmed Interactions
Patients’ Use and Perceptions of a Drug-Drug Interaction Database: A Survey of Janusmed Interactions Open
Janusmed interactions is a drug-drug interactions (DDI) database available online for healthcare professionals (HCP) at all levels of the healthcare system including pharmacies. The database is aimed at HCP but is also open to the public f…
View article: Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet
Guiding principles for the use of knowledge bases and real-world data in clinical decision support systems: report by an international expert workshop at Karolinska Institutet Open
Evidence-based, publicly funded, well-structured and curated knowledge bases are of global importance. They ought to be considered as a public responsibility requiring transparency and handling of conflicts of interest. Information has to …
View article: The effect of simvastatin on warfarin anticoagulation: a Swedish register-based nationwide cohort study
The effect of simvastatin on warfarin anticoagulation: a Swedish register-based nationwide cohort study Open
In conclusion, initiation of simvastatin resulted in moderately increased INR values and subsequent dose decreases in patients already on warfarin. In order to avoid the increased risk of bleeding, the initiation of simvastatin may be acco…
View article: Clinical relevance of alerts from a decision support system, PHARAO, for drug safety assessment in the older adults
Clinical relevance of alerts from a decision support system, PHARAO, for drug safety assessment in the older adults Open
The PHARAO system had a high specificity and negative predictive value to detect symptoms possibly associated with the of patients' medications, while the sensitivity and positive predictive value were low. The PHARAO system has the potent…
View article: Is tramadol associated to bleeding peptic ulcer? A nationwide case-control study in hospitalized Swedish patients
Is tramadol associated to bleeding peptic ulcer? A nationwide case-control study in hospitalized Swedish patients Open
Treatment with tramadol was associated with an increased risk of bleeding peptic ulcer. Most of this association may be mediated by factors related to the pain condition rather than the pharmacologic effect per se.
View article: Development and pilot testing of PHARAO—a decision support system for pharmacological risk assessment in the elderly
Development and pilot testing of PHARAO—a decision support system for pharmacological risk assessment in the elderly Open
The PHARAO decision support system, designed as a complement to a database on drug-drug interactions used nationally, worked as intended and was appreciated by the users during a 4-month test period. Integration aspects need to be improved…
View article: High Prevalence of Drug–Drug Interactions in Primary Health Care is Caused by Prescriptions from other Healthcare Units
High Prevalence of Drug–Drug Interactions in Primary Health Care is Caused by Prescriptions from other Healthcare Units Open
Drug–drug interactions are increasingly common, as patients are getting older and the number of drugs per patient is increasing. In this study, we investigated to which extent potential drug–drug interactions originated from single or mult…