Mario Werkmann
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View article: Effects of Nabilone on Sleep Outcomes in Patients with Parkinson's Disease: A Post‐hoc Analysis of <scp>NMS‐Nab</scp> Study
Effects of Nabilone on Sleep Outcomes in Patients with Parkinson's Disease: A Post‐hoc Analysis of <span>NMS‐Nab</span> Study Open
Background The synthetic tetrahydrocannabinol analogue nabilone improved overall non‐motor symptom (NMS) burden in Parkinson's disease (PD) patients in comparison to placebo. Objectives To characterize the effects of nabilone on different …
View article: On the recovery of disorders of consciousness under intrathecal baclofen administration for severe spasticity—An observational study
On the recovery of disorders of consciousness under intrathecal baclofen administration for severe spasticity—An observational study Open
Background Occasionally, patients show dramatic recovery from disorders of consciousness (DOC) under intrathecal baclofen (ITB), an established treatment option for severe supraspinal spasticity. Anecdotal explanations for ITB‐related reco…
View article: Rapid eye movement sleep behavior disorder and rapid eye movement sleep without atonia are more frequent in advanced versus early Parkinson’s disease
Rapid eye movement sleep behavior disorder and rapid eye movement sleep without atonia are more frequent in advanced versus early Parkinson’s disease Open
Study Objectives To evaluate macro sleep architecture and characterize rapid eye movement (REM) sleep without atonia (RWA) by using the SINBAR excessive electromyographic (EMG) montage including mentalis and upper extremity muscles in earl…
View article: Issue Information
Issue Information Open
Movement Disorders Clinical Practice-is an online-only journal committed to publishing high quality peer reviewed articles related to clinical aspects of movement disorders which broadly include phenomenology (interesting case/case series/…
View article: Augmentation in restless legs syndrome: an eye tracking study on emotion processing
Augmentation in restless legs syndrome: an eye tracking study on emotion processing Open
Objective To assess emotional processing and alexithymia in patients with restless legs syndrome (RLS) with augmentation versus those who never had augmentation. Methods We recruited 26 patients who had a history of augmentation (AUG), eit…
View article: Non‐Motor Symptoms in Parkinson's Disease are Reduced by Nabilone
Non‐Motor Symptoms in Parkinson's Disease are Reduced by Nabilone Open
Objective The objective of this study was to assess the efficacy and safety of nabilone, a synthetic tetrahydrocannabinol analogue, as a treatment for non‐motor symptoms (NMS) in Parkinson's disease (PD). Methods This was a phase II placeb…
View article: Has Deep Brain Stimulation Changed the Very Long‐Term Outcome of Parkinson's Disease? A Controlled Longitudinal Study
Has Deep Brain Stimulation Changed the Very Long‐Term Outcome of Parkinson's Disease? A Controlled Longitudinal Study Open
Background The long‐term impact of deep brain stimulation (DBS) on Parkinson's disease (PD) is difficult to assess and has not yet been rigorously evaluated in comparison to its natural history. Objective Comparison of key disability miles…
View article: Seeing ophthalmologic problems in Parkinson disease
Seeing ophthalmologic problems in Parkinson disease Open
Patients with PD have a higher prevalence of ophthalmologic symptoms than controls. Moreover, these frequently interfere with daily activities. A screening questionnaire such as the VIPD-Q may help with identifying ophthalmologic symptoms …
View article: Nabilone for non-motor symptoms of Parkinson’s disease: a randomized placebo-controlled, double-blind, parallel-group, enriched enrolment randomized withdrawal study (The NMS-Nab Study)
Nabilone for non-motor symptoms of Parkinson’s disease: a randomized placebo-controlled, double-blind, parallel-group, enriched enrolment randomized withdrawal study (The NMS-Nab Study) Open
Although open-label observations report a positive effect of cannabinoids on non-motor symptoms (NMS) in Parkinson's disease (PD) patients, these effects remain to be investigated in a controlled trial for a broader use in NMS in PD patien…