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View article: miR-28-5p and miR-708-5p Share a Common Seed with Different Functions in Lung Cancer Patients
miR-28-5p and miR-708-5p Share a Common Seed with Different Functions in Lung Cancer Patients Open
Lung cancer remains the leading cause of cancer-related mortality worldwide, accounting for nearly 1.8 million deaths annually. The present study aimed to investigate the role of miR-28-5p and miR-708-5p in lung cancer and to analyze the r…
View article: The Genomic Landscape of Romanian Non-Small Cell Lung Cancer Patients: The Insights from Routine NGS Testing with the Oncomine™ Dx Express Test at the PATHOS Molecular Pathology Laboratory
The Genomic Landscape of Romanian Non-Small Cell Lung Cancer Patients: The Insights from Routine NGS Testing with the Oncomine™ Dx Express Test at the PATHOS Molecular Pathology Laboratory Open
Background: Comprehensive molecular profiling is essential for precision oncology in non-small cell lung cancer (NSCLC). However, genomic data from Eastern European populations, including Romania, remain limited. Methods: We analyzed 398 c…
View article: AI-powered evaluation of lung function for diagnosis of interstitial lung disease
AI-powered evaluation of lung function for diagnosis of interstitial lung disease Open
Background The diagnosis of interstitial lung disease (ILD) can pose a challenge as the pulmonary function test (PFT) is only minimally affected at the onset. To improve early diagnosis, this study aims to explore the potential of artifici…
View article: Identification of Potential microRNA Panels for Male Non-Small Cell Lung Cancer Identification Using Microarray Datasets and Bioinformatics Methods
Identification of Potential microRNA Panels for Male Non-Small Cell Lung Cancer Identification Using Microarray Datasets and Bioinformatics Methods Open
Background: Non-small cell lung cancer (NSCLC) is still one of the types of cancer with the highest death rates. MicroRNAs (miRNAs) play essential roles in NSCLC development. This study evaluates miRNA expression patterns and specific mech…
View article: Next-Generation Sequencing in Lung Cancer Patients: A Comparative Approach in NSCLC and SCLC Mutational Landscapes
Next-Generation Sequencing in Lung Cancer Patients: A Comparative Approach in NSCLC and SCLC Mutational Landscapes Open
Background: Lung cancer remains one of the most diagnosed malignancies, being the second most diagnosed cancer, while still being the leading cause of cancer-related deaths. Late diagnosis remains a problem, alongside the high mutational b…
View article: Cryobiopsy in Lung Cancer Diagnosis—A Literature Review
Cryobiopsy in Lung Cancer Diagnosis—A Literature Review Open
Optimizing the diagnosis of lung cancer represents a challenge, as well as a necessity, for improving the low survival of these patients. Flexible bronchoscopy with forceps biopsy is one of the key diagnostic procedures used for lung tumor…
View article: EBUS in optimizing non-small cell lung cancer diagnosis and treatment
EBUS in optimizing non-small cell lung cancer diagnosis and treatment Open
Background. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a commonly used minimally invasive method for the diagnosis and staging of lung cancer. In order to improve its diagnostic accuracy, rapid on-site …
View article: Noncoding RNAs and Liquid Biopsy in Lung Cancer: A Literature Review
Noncoding RNAs and Liquid Biopsy in Lung Cancer: A Literature Review Open
Lung cancer represents a genetically heterogeneous disease with low survival rates. Recent data have evidenced key roles of noncoding RNAs in lung cancer initiation and progression. These functional RNA molecules that can act as both oncog…
View article: <p>SERS-based differential diagnosis between multiple solid malignancies: breast, colorectal, lung, ovarian and oral cancer</p>
SERS-based differential diagnosis between multiple solid malignancies: breast, colorectal, lung, ovarian and oral cancer Open
SERS on serum represents a promising strategy of diagnosing cancer which can discriminate between cancer patients and controls, as well as between cancer types such as breast, colorectal, lung ovarian and oral cancer.
View article: Soluble sPD-L1 and serum amyloid A1 as potential biomarkers for lung cancer
Soluble sPD-L1 and serum amyloid A1 as potential biomarkers for lung cancer Open
Summary Background The objective of this prospective study was to evaluate whether soluble programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) and serum amyloid A1 (SAA1) are potential diagnostic, predictive or prognostic b…
View article: Current Practice of Airway Stenting in the Adult Population in Europe: A Survey of the European Association of Bronchology and Interventional Pulmonology (EABIP)
Current Practice of Airway Stenting in the Adult Population in Europe: A Survey of the European Association of Bronchology and Interventional Pulmonology (EABIP) Open
Background: Airway stenting (AS) commenced in Europe circa 1987 with the first placement of a dedicated silicone airway stent. Subsequently, over the last 3 decades, AS was spread throughout Europe, using different insertion …
View article: ENDOBRONCHIAL ULTRASOUND – ONE YEAR OF EXPERIENCE IN CLINICAL PRACTICE
ENDOBRONCHIAL ULTRASOUND – ONE YEAR OF EXPERIENCE IN CLINICAL PRACTICE Open
Background and aim. Endobronchial ultrasound (EBUS) is a recent minimally invasive, safe examination method for the mediastinum, with a good diagnostic precision.This method makes possible real time examination with transbronchial fine nee…