Marion Bendayan
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View article: Recommendations for Human Sperm Morphology Assessment in 2025: An Expert Review From the French BLEFCO Group
Recommendations for Human Sperm Morphology Assessment in 2025: An Expert Review From the French BLEFCO Group Open
Background Numerous publications have questioned the lack of analytical reliability and clinical relevance of sperm morphology assessment for infertility workup and before use of assisted reproductive techniques (ART). There is a huge vari…
View article: The Combined Expression Profiles of Epigenetic Biomarkers Reveal Heterogeneity in Normospermic Human Sperm Samples
The Combined Expression Profiles of Epigenetic Biomarkers Reveal Heterogeneity in Normospermic Human Sperm Samples Open
Background: Male infertility is evaluated using standard semen parameters. However, these criteria offer limited insight into sperm functionality and poorly predict natural fertility or assisted reproductive technology (ART) outcomes. Meth…
View article: Congenital absence of vas deferens: Anatomical and embryological inputs from a series of autopsies reported in Europe throughout the 18th and 19th century
Congenital absence of vas deferens: Anatomical and embryological inputs from a series of autopsies reported in Europe throughout the 18th and 19th century Open
Congenital absence of the vas deferens (CAVD) is a syndrome with a heterogeneous presentation: bilateral (CBAVD) or unilateral (CUAVD), complete or partial and associated or not with other anomalies of the male urogenital system. A turning…
View article: COVID‐19 and Oncofertility: No SARS‐CoV‐2 in Semen but Inflammation Seems to Affect Sperm Parameters
COVID‐19 and Oncofertility: No SARS‐CoV‐2 in Semen but Inflammation Seems to Affect Sperm Parameters Open
The COVID‐19 pandemic, driven by SARS‐CoV‐2, led authorities to recommend halting assisted reproductive technology programs, focusing instead on fertility preservation, for cancer patients. The presence of SARS‐CoV‐2 in semen remains contr…
View article: Global Practice Patterns and Variations in the Medical and Surgical Management of Non-Obstructive Azoospermia: Results of a World-Wide Survey, Guidelines and Expert Recommendations
Global Practice Patterns and Variations in the Medical and Surgical Management of Non-Obstructive Azoospermia: Results of a World-Wide Survey, Guidelines and Expert Recommendations Open
This is the largest survey to date on the real-world medical and surgical management of NOA by reproductive experts. It demonstrates a diverse practice pattern and highlights the need for evidence-based international consensus guidelines.
View article: Global Practice Patterns in the Evaluation of Non-Obstructive Azoospermia: Results of a World-Wide Survey and Expert Recommendations
Global Practice Patterns in the Evaluation of Non-Obstructive Azoospermia: Results of a World-Wide Survey and Expert Recommendations Open
This expert survey, encompassing 367 participants from 49 countries, unveils congruence with recommended guidelines in NOA diagnosis. However, noteworthy disparities in practices suggest a need for evidence-based, international consensus g…
View article: Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data
Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data Open
Purpose: The purpose of this meta-analysis is to study the impact of varicocele repair in the largest cohort of infertile males with clinical varicocele by including all available studies, with no language restrictions, comparing intra-per…
View article: P-392 Controlled ovarian hyperstimulation applied before unilateral oophorectomy improves fertility preservation in cancer patients
P-392 Controlled ovarian hyperstimulation applied before unilateral oophorectomy improves fertility preservation in cancer patients Open
Study question Can ovarian tissue cryopreservation (OTC) be performed after controlled ovarian hyperstimulation (COH)? Summary answer Unilateral oophorectomy after transvaginal oocyte retrieval is feasible on stimulated ovaries during one …
View article: P-460 The Impact of Assisted Reproductive Technologies on Climate Change : The French Case
P-460 The Impact of Assisted Reproductive Technologies on Climate Change : The French Case Open
Study question How much tons of carbon dioxide equivalent (tCO2e) are generated by Assisted Reproductive Technologies in France in a year ? Summary answer It is estimated that Assisted Reproductive Technologies generated 55 691 tons of car…
View article: P-039 Pregnancy outcomes and genetic analysis of globozoospermic patients: A case series and review of the literature
P-039 Pregnancy outcomes and genetic analysis of globozoospermic patients: A case series and review of the literature Open
Study question How should men with globozoospermia be managed in Assisted Reproductive Technologies (ART)? Summary answer IMSI (intracytoplasmic morphologically selected sperm injection), without oocyte activators (OA) allows to obtain a l…
View article: Controversy and Consensus on the Management of Elevated Sperm DNA Fragmentation in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations
Controversy and Consensus on the Management of Elevated Sperm DNA Fragmentation in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations Open
This paper presents the results of a large global survey on the management of infertile men with elevated SDF and reveals a lack of consensus among clinicians. Furthermore, it demonstrates the scarcity of professional society guidelines in…
View article: Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis
Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis Open
This study provides a high level of evidence in favor of a positive effect of VR to improve conventional semen parameters in infertile men with clinical varicocele. To the best of our knowledge, this is the first SRMA to compare changes in…
View article: Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations
Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations Open
This study is the largest global survey performed to date on the clinical management of varicocele for male infertility. It demonstrates: 1) a wide disagreement in the approach to varicocele management, 2) large gaps in the clinical practi…
View article: Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic Pattern
Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic Pattern Open
Background: Human sperm chromatin condensation is a sum of epigenetic events that allows for the near-complete replacement of histones with protamines. Under high-magnification microscopy, nuclear vacuoles have been described as thumbprint…
View article: COVID-19: semen impairment may not be related to the virus
COVID-19: semen impairment may not be related to the virus Open
International audience
View article: What could cause the long-term effects of COVID-19 on sperm parameters and male fertility?
What could cause the long-term effects of COVID-19 on sperm parameters and male fertility? Open
International audience
View article: COVID‐19 in men: With or without virus in semen, spermatogenesis may be impaired
COVID‐19 in men: With or without virus in semen, spermatogenesis may be impaired Open
International audience
View article: Predicting sperm extraction in non-obstructive azoospermia patients
Predicting sperm extraction in non-obstructive azoospermia patients Open
The human intestine harbours a complex and diverse bacterial community called the gut microbiota.This microbiota, stable during the lifetime, is specific of each individual despite the existence of a phylogenetic core shared by the majorit…