Marion Steger
YOU?
Author Swipe
View article: Clonal Hematopoiesis of Indeterminate Potential and Diabetic Kidney Disease: A Nested Case-Control Study
Clonal Hematopoiesis of Indeterminate Potential and Diabetic Kidney Disease: A Nested Case-Control Study Open
View article: Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses
Complement Potentiates Immune Sensing of HIV-1 and Early Type I Interferon Responses Open
Importantly, our study highlights an unusual target on DCs—the α chain of complement receptor 4 (CR4) (CD11c)—for therapeutic interventions in HIV-1 treatment. Targeting CD11c on DCs mediated a potent antiviral immune response via clusteri…
View article: β-1,3-glucan-lacking<i>Aspergillus fumigatus</i>mediates an efficient antifungal immune response by activating complement and dendritic cells
β-1,3-glucan-lacking<i>Aspergillus fumigatus</i>mediates an efficient antifungal immune response by activating complement and dendritic cells Open
Complement system and dendritic cells (DCs) form - beside neutrophils and macrophages - the first line of defense to combat fungal infections. Therefore, we here studied interactions of these first immune elements with Aspergillus fumig…
View article: β-1,3-glucan-lacking <i>Aspergillus fumigatus</i> mediates an efficient antifungal immune response by activating complement and dendritic cells
β-1,3-glucan-lacking <i>Aspergillus fumigatus</i> mediates an efficient antifungal immune response by activating complement and dendritic cells Open
Complement system and dendritic cells (DCs) form – beside neutrophils and macrophages – the first line of defense to combat fungal infections. Therefore, we here studied interactions of these first immune elements with Aspergillus fumig…
View article: β-1,3-glucan-lacking <i>Aspergillus fumigatus</i> mediates an efficient antifungal immune response by activating complement and dendritic cells
β-1,3-glucan-lacking <i>Aspergillus fumigatus</i> mediates an efficient antifungal immune response by activating complement and dendritic cells Open
Complement system and dendritic cells (DCs) form – beside neutrophils and macrophages – the first line of defense to combat fungal infections. Therefore, we here studied interactions of these first immune elements with Aspergillus fumig…
View article: Fast-track development of an in vitro 3D lung/immune cell model to study Aspergillus infections
Fast-track development of an in vitro 3D lung/immune cell model to study Aspergillus infections Open
View article: Oxidative Stress Response Tips the Balance in Aspergillus terreus Amphotericin B Resistance
Oxidative Stress Response Tips the Balance in Aspergillus terreus Amphotericin B Resistance Open
In this study, we characterize the impact of antioxidative enzymes in amphotericin B (AmB)-resistant (ATR) and rare AmB-susceptible (ATS) clinical Aspergillus terreus isolates. We elucidate expression profiles of superoxide dismutase (SOD)…
View article: Promising immunotherapy against fungal diseases
Promising immunotherapy against fungal diseases Open
Despite the relatively high efficacy of antifungal drugs, invasive fungal infections (IFIs) are still associated with tremendous morbidity and mortality, since late diagnosis makes an antifungal drug therapy inefficient. Therefore, antifun…
View article: Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells
Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells Open
DCs express intrinsic cellular defense mechanisms to specifically inhibit HIV-1 replication. Thus, DCs are productively infected only at very low levels with HIV-1, and this non-permissiveness of DCs is suggested to go along with viral eva…