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View article: Usability and feasibility assessment of the Huntington Support App (HD-eHelp study): a mixed-methods multi-study report
Usability and feasibility assessment of the Huntington Support App (HD-eHelp study): a mixed-methods multi-study report Open
Background eHealth holds great promise for managing rare and complex neurodegenerative diseases, such as Huntington’s disease (HD). To address this potential, the Huntington Support App (HSA) was developed to provide reliable information o…
View article: Adaptación y validación de la escala mexicana de evaluación de la calidad de vida en adultos con deficiencia de hormona de crecimiento (QoL-AGHDA)
Adaptación y validación de la escala mexicana de evaluación de la calidad de vida en adultos con deficiencia de hormona de crecimiento (QoL-AGHDA) Open
Antecedentes: La deficiencia de hormona de crecimiento (GHD), causada por disminución en la secreción por la hipófisis, tiene repercusiones clínicas que impactan en la composición corporal, parámetros metabólicos y puede tener impacto nega…
View article: Adaptation and validation of the Mexican Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA)
Adaptation and validation of the Mexican Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA) Open
View article: Emotional problems and urinary incontinence in children from a UK cohort
Emotional problems and urinary incontinence in children from a UK cohort Open
Children with UI experience increased emotional problems over time and changes in emotional problems were associated with subsequent UI. Emotional problems should be evaluated in children treated for incontinence.
View article: One-minute sit-to-stand test cut-offs for risk stratification based on six-minute walk test thresholds in pulmonary hypertension
One-minute sit-to-stand test cut-offs for risk stratification based on six-minute walk test thresholds in pulmonary hypertension Open
Aims We aimed to establish 1-min sit-to-stand test (1-min STST) cut-off values that align with the guideline-recommended 6-min walk test (6MWT) thresholds (165 and 440 m) for 1-year mortality risk stratification in pulmonary hypertension (…
View article: Sleep duration, sleep problems and developmental trajectories of urinary incontinence: a prospective cohort study
Sleep duration, sleep problems and developmental trajectories of urinary incontinence: a prospective cohort study Open
To examine if preschool sleep duration and sleep problems are associated with urinary incontinence (UI) at primary school-age. We used multinomial logistic regression to examine the association of child sleep duration/problems (3½ years) w…
View article: Assessing the effectiveness of artificial intelligence (AI) in prioritising CT head interpretation: study protocol for a stepped-wedge cluster randomised trial (ACCEPT-AI)
Assessing the effectiveness of artificial intelligence (AI) in prioritising CT head interpretation: study protocol for a stepped-wedge cluster randomised trial (ACCEPT-AI) Open
Introduction Diagnostic imaging is vital in emergency departments (EDs). Accessibility and reporting impacts ED workflow and patient care. With radiology workforce shortages, reporting capacity is limited, leading to image interpretation d…
View article: The one-minute sit-to-stand-test performance is associated with health-related quality of life in patients with pulmonary hypertension
The one-minute sit-to-stand-test performance is associated with health-related quality of life in patients with pulmonary hypertension Open
Introduction Patients with pulmonary hypertension (PH) have an impaired functional capacity and poor health-related quality of life (HRQoL). The one-minute sit-to-stand test (1-min STST) can be used for the assessment of functional capacit…
View article: Artificial intelligence for abnormality detection in high volume neuroimaging: a systematic review and meta-analysis
Artificial intelligence for abnormality detection in high volume neuroimaging: a systematic review and meta-analysis Open
Purpose: Most studies evaluating artificial intelligence (AI) models that detect abnormalities in neuroimaging are either tested on unrepresentative patient cohorts or are insufficiently well-validated, leading to poor generalisability to …
View article: AI assisted reader evaluation in acute CT head interpretation (AI-REACT): protocol for a multireader multicase study
AI assisted reader evaluation in acute CT head interpretation (AI-REACT): protocol for a multireader multicase study Open
Introduction A non-contrast CT head scan (NCCTH) is the most common cross-sectional imaging investigation requested in the emergency department. Advances in computer vision have led to development of several artificial intelligence (AI) to…
View article: Author response to: Comment on: Intraoperative bowel perfusion assessment methods and their effects on anastomotic leak rates: meta-analysis
Author response to: Comment on: Intraoperative bowel perfusion assessment methods and their effects on anastomotic leak rates: meta-analysis Open
Extended lymph node dissection for rectal cancer, is it still under debate
View article: Sleep duration, sleep problems and developmental trajectories of urinary incontinence: a prospective cohort study
Sleep duration, sleep problems and developmental trajectories of urinary incontinence: a prospective cohort study Open
Objective To examine if sleep duration and sleep problems are associated with urinary incontinence (UI) in children. Methods We used multinomial logistic regression to examine the association of child sleep duration/problems at 3½ years wi…
View article: Systematic Review of Artificial Intelligence for Abnormality Detection in High-volume Neuroimaging and Subgroup Meta-analysis for Intracranial Hemorrhage Detection
Systematic Review of Artificial Intelligence for Abnormality Detection in High-volume Neuroimaging and Subgroup Meta-analysis for Intracranial Hemorrhage Detection Open
Purpose Most studies evaluating artificial intelligence (AI) models that detect abnormalities in neuroimaging are either tested on unrepresentative patient cohorts or are insufficiently well-validated, leading to poor generalisability to r…
View article: Intraoperative bowel perfusion assessment methods and their effects on anastomotic leak rates: meta-analysis
Intraoperative bowel perfusion assessment methods and their effects on anastomotic leak rates: meta-analysis Open
Background Anastomotic leak is one of the most feared complications of colorectal surgery, and probably linked to poor blood supply to the anastomotic site. Several technologies have been described for intraoperative assessment of bowel pe…
View article: Delayed post gadolinium MRI descriptors for Meniere’s disease: a systematic review and meta-analysis
Delayed post gadolinium MRI descriptors for Meniere’s disease: a systematic review and meta-analysis Open
View article: Association of dynamic contrast-enhanced MRI and 18F-Fluorodeoxyglucose PET/CT parameters with neoadjuvant therapy response and survival in esophagogastric cancer
Association of dynamic contrast-enhanced MRI and 18F-Fluorodeoxyglucose PET/CT parameters with neoadjuvant therapy response and survival in esophagogastric cancer Open
View article: Detection of cerebral aneurysms using artificial intelligence: a systematic review and meta-analysis
Detection of cerebral aneurysms using artificial intelligence: a systematic review and meta-analysis Open
Background Subarachnoid hemorrhage from cerebral aneurysm rupture is a major cause of morbidity and mortality. Early aneurysm identification, aided by automated systems, may improve patient outcomes. Therefore, a systematic review and meta…
View article: Developing decision support tools incorporating personalised predictions of likely visual benefit versus harm for cataract surgery: research programme
Developing decision support tools incorporating personalised predictions of likely visual benefit versus harm for cataract surgery: research programme Open
Background Surgery for established cataract is highly cost-effective and uncontroversial, yet uncertainty remains for individuals about when to proceed and when to delay surgery during the earlier stages of cataract. Objective We aimed to …
View article: Imaging Biomarkers of Glioblastoma Treatment Response: A Systematic Review and Meta-Analysis of Recent Machine Learning Studies
Imaging Biomarkers of Glioblastoma Treatment Response: A Systematic Review and Meta-Analysis of Recent Machine Learning Studies Open
Objective Monitoring biomarkers using machine learning (ML) may determine glioblastoma treatment response. We systematically reviewed quality and performance accuracy of recently published studies. Methods Following Preferred Reporting Ite…
View article: OS08.6.A Glioblastoma treatment response machine learning monitoring biomarkers: a systematic review and meta-analysis
OS08.6.A Glioblastoma treatment response machine learning monitoring biomarkers: a systematic review and meta-analysis Open
BACKGROUND The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). MATERIAL AND METH…
View article: P-265 Neoadjuvant radiotherapy for locally advanced rectal cancer during the first wave of COVID19 pandemic: Guy’s cancer cohort experience
P-265 Neoadjuvant radiotherapy for locally advanced rectal cancer during the first wave of COVID19 pandemic: Guy’s cancer cohort experience Open
View article: Clinical utility of DaTscan in patients with suspected Parkinsonian syndrome: a systematic review and meta-analysis
Clinical utility of DaTscan in patients with suspected Parkinsonian syndrome: a systematic review and meta-analysis Open
View article: The development and validation of the CARe Burn Scale: Child Form: a parent-proxy-reported outcome measure assessing quality of life for children aged 8 years and under living with a burn injury
The development and validation of the CARe Burn Scale: Child Form: a parent-proxy-reported outcome measure assessing quality of life for children aged 8 years and under living with a burn injury Open
View article: Challenging the view that lack of fibre causes childhood constipation
Challenging the view that lack of fibre causes childhood constipation Open
Objectives To assess evidence supporting the view that ‘low fibre causes childhood constipation’. Design Triangulation integrated three approaches: a systematic review NICE guideline CG99 examining effectiveness of increasing fibre; a coho…
View article: Assessing the construct validity and responsiveness of Preference-Based Measures (PBMs) in cataract surgery patients
Assessing the construct validity and responsiveness of Preference-Based Measures (PBMs) in cataract surgery patients Open
View article: An 11-year analysis of microbial keratitis in the South West of England using brain–heart infusion broth
An 11-year analysis of microbial keratitis in the South West of England using brain–heart infusion broth Open
View article: The Royal College of Ophthalmologists’ National Ophthalmology Database Study of cataract surgery. Report 5: Clinical outcome and risk factors for posterior capsule rupture and visual acuity loss following cataract surgery in patients aged 90 years and older
The Royal College of Ophthalmologists’ National Ophthalmology Database Study of cataract surgery. Report 5: Clinical outcome and risk factors for posterior capsule rupture and visual acuity loss following cataract surgery in patients aged 90 years and older Open
View article: A prospective cohort study of biopsychosocial factors associated with childhood urinary incontinence
A prospective cohort study of biopsychosocial factors associated with childhood urinary incontinence Open
View article: The development and validation of the CARe Burn Scales: A portfolio of patient reported outcome measures (PROMs) for use in paediatric and adult burn care
The development and validation of the CARe Burn Scales: A portfolio of patient reported outcome measures (PROMs) for use in paediatric and adult burn care Open
View article: Psychosocial risks for constipation and soiling in primary school children
Psychosocial risks for constipation and soiling in primary school children Open