Marjo Hiekkala
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View article: Diagnosing migraine from genome-wide genotype data: a machine learning analysis
Diagnosing migraine from genome-wide genotype data: a machine learning analysis Open
Migraine has an assumed polygenic basis, but the genetic risk variants identified in genome-wide association studies only explain a proportion of the heritability. We aimed to develop machine learning models, capturing non-additive and int…
View article: A causal effects of gut microbiota in the development of migraine
A causal effects of gut microbiota in the development of migraine Open
View article: Elucidating the relationship between migraine risk and brain structure using genetic data
Elucidating the relationship between migraine risk and brain structure using genetic data Open
Migraine is a highly common and debilitating disorder that often affects individuals in their most productive years of life. Previous studies have identified both genetic variants and brain morphometry differences associated with migraine …
View article: Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families
Common Variant Burden Contributes to the Familial Aggregation of Migraine in 1,589 Families Open
View article: Common variant burden contributes significantly to the familial aggregation of migraine in 1,589 families
Common variant burden contributes significantly to the familial aggregation of migraine in 1,589 families Open
It has long been observed that complex traits, including migraine, often aggregate in families, but the underlying genetic architecture behind this is not well understood. Two competing hypotheses exist, emphasizing either rare or common g…