Marjon Kamp
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View article: Regulation of G-proteins during chemotaxis in space and time
Regulation of G-proteins during chemotaxis in space and time Open
The coordinated movement of cells in a gradient of a chemical substance (chemo-attractant) is called chemotaxis. The gradient is translated to cell movement towards the chemo-attractant by a signal transduction pathway inside the cell. Che…
View article: G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation
G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation Open
Fermentation of dietary fibre in the gut yields large amounts of short chain fatty acids (SCFAs). SCFAs can impart biological responses in cells through their engagement of 'metabolite-sensing' G protein-coupled receptors (GPCRs). One of t…
View article: Function and Regulation of Heterotrimeric G Proteins during Chemotaxis
Function and Regulation of Heterotrimeric G Proteins during Chemotaxis Open
Chemotaxis, or directional movement towards an extracellular gradient of chemicals, is necessary for processes as diverse as finding nutrients, the immune response, metastasis and wound healing. Activation of G-protein coupled receptors (G…