Mark R. Bonnell
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View article: Right Ventricular Dysfunction and Short‐Term Outcomes Following Left‐Sided Valvular Surgery: An Echocardiographic Study
Right Ventricular Dysfunction and Short‐Term Outcomes Following Left‐Sided Valvular Surgery: An Echocardiographic Study Open
Background The prognostic value of echocardiographic evaluation of right ventricular (RV) function in patients undergoing left‐sided valvular surgery has not been well described. The objective of this study is to determine the role of broa…
View article: Orthopedic Principles to Facilitate Enhanced Recovery After Cardiac Surgery
Orthopedic Principles to Facilitate Enhanced Recovery After Cardiac Surgery Open
Enhanced recovery after surgery (ERAS) protocols recognize early postoperative mobilization as a driver of faster postoperative recovery, return to normal activities, and improved long-term patient outcomes. For patients undergoing open ca…
View article: An Emergency Medicine–focused Summary of the HFSA/SAEM/ISHLT Clinical Consensus Document on the Emergency Management of Patients With Ventricular Assist Devices
An Emergency Medicine–focused Summary of the HFSA/SAEM/ISHLT Clinical Consensus Document on the Emergency Management of Patients With Ventricular Assist Devices Open
Mechanical circulatory support is increasingly used as a long‐term treatment option for patients with end‐stage heart failure. Patients with implanted ventricular assist devices are at high risk for a range of diverse medical urgencies and…
View article: The effect of completeness of revascularization during CABG with single versus multiple arterial grafts
The effect of completeness of revascularization during CABG with single versus multiple arterial grafts Open
Incomplete revascularization is associated with decreased late survival, irrespective of grafting strategy. Alternatively, supra-complete revascularization is associated with improved survival in patients with 3-Vessel CAD, and in single-a…
View article: Sternotomy closure using rigid plate fixation: a paradigm shift from wire cerclage
Sternotomy closure using rigid plate fixation: a paradigm shift from wire cerclage Open
Sternotomy closure with RPF resulted in significantly better sternal healing, fewer sternal complications, improved PROMs and was cost neutral through 90 days and 6 months compared to WC.
View article: Evidence and temporality of the obesity paradox in coronary bypass surgery: an analysis of cause-specific mortality†
Evidence and temporality of the obesity paradox in coronary bypass surgery: an analysis of cause-specific mortality† Open
We identified a protective partial obesity paradox in the early and intermediate postoperative periods among Overweight and mildly obese (Obese I) patients with improved CV and non-CV survival. The morbidly obese (the Obese III group) had …
View article: Effect of new-onset atrial fibrillation on cause-specific late mortality after coronary artery bypass grafting surgery†
Effect of new-onset atrial fibrillation on cause-specific late mortality after coronary artery bypass grafting surgery† Open
POAF is associated with worse long-term survival principally driven by increased intermediate-term cerebrovascular and cardiovascular mortality, while Non-CV mortality was similar.
View article: Rigid Plate Fixation Versus Wire Cerclage: Patient-Reported and Economic Outcomes From a Randomized Trial
Rigid Plate Fixation Versus Wire Cerclage: Patient-Reported and Economic Outcomes From a Randomized Trial Open
In patients undergoing sternal closure after median sternotomy, RPF compared with WC resulted in reduced sternal pain, improved upper extremity function, and similar total 90-day costs.
View article: Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation
Diaphragm Abnormalities in Patients with End-Stage Heart Failure: NADPH Oxidase Upregulation and Protein Oxidation Open
Patients with heart failure (HF) have diaphragm abnormalities that contribute to disease morbidity and mortality. Studies in animals suggest that reactive oxygen species (ROS) cause diaphragm abnormalities in HF. However, the effects of HF…
View article: Randomized, multicenter trial comparing sternotomy closure with rigid plate fixation to wire cerclage
Randomized, multicenter trial comparing sternotomy closure with rigid plate fixation to wire cerclage Open
Sternotomy closure with rigid plate fixation resulted in significantly better sternal healing, fewer sternal complications, and no additional cost compared with wire cerclage at 6 months after surgery.
View article: A Protocol for Collecting Human Cardiac Tissue for Research
A Protocol for Collecting Human Cardiac Tissue for Research Open
This manuscript describes a protocol at the University of Kentucky that allows a translational research team to collect human myocardium that can be used for biological research. We have gained a great deal of practical experience si…
View article: A Protocol for Collecting Human Cardiac Tissue for Research
A Protocol for Collecting Human Cardiac Tissue for Research Open
This manuscript describes a protocol at the University of Kentucky that allows a translational research team to collect human myocardium that can be used for biological research. We have gained a great deal of practical experience since we…
View article: Equipoise between radial artery and right internal thoracic artery as the second arterial conduit in left internal thoracic artery-based coronary artery bypass graft surgery: a multi-institutional study
Equipoise between radial artery and right internal thoracic artery as the second arterial conduit in left internal thoracic artery-based coronary artery bypass graft surgery: a multi-institutional study Open
RA-MABG or RITA-MABG equally improve long-term survival compared with SABG and thus should be embraced by the Heart Team as the therapy of choice in LITA-based coronary artery bypass surgery.