Mark C. Bicket
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View article: Postpartum Pain Management: A Systematic Review To Support Clinical Practice Guideline Development
Postpartum Pain Management: A Systematic Review To Support Clinical Practice Guideline Development Open
View article: A New Class of Mark-Specific Proportional Hazards Models for Recurrent Events: Application to Opioid Refills Among Post-Surgical Patients
A New Class of Mark-Specific Proportional Hazards Models for Recurrent Events: Application to Opioid Refills Among Post-Surgical Patients Open
Prescription opioids relieve moderate-to-severe pain after surgery, but overprescription can lead to misuse and overdose. Understanding factors associated with post-surgical opioid refills is crucial for improving pain management and reduc…
View article: National trends in naloxone codispensing with outpatient opioid prescriptions, 2013–2023
National trends in naloxone codispensing with outpatient opioid prescriptions, 2013–2023 Open
Background Increasing access to naloxone, an opioid antagonist, can prevent opioid overdose among patients prescribed opioids. In 2016, the Centers for Disease Control and Prevention recommended coprescribing naloxone with opioids; however…
View article: Guidelines From the American Society of Pain and Neuroscience for Using Artificial Intelligence in Interventional Spine and Nerve Treatment
Guidelines From the American Society of Pain and Neuroscience for Using Artificial Intelligence in Interventional Spine and Nerve Treatment Open
The field of artificial intelligence is rapidly growing. As it expands into healthcare, it is necessary to prevent breaches of sensitive data and potential harm to patients. Guidelines that constantly evolve and grow with expanding indicat…
View article: Impact of COVID-19 on Opioid Prescribing, Consumption, Pain, and Outcomes after Surgery
Impact of COVID-19 on Opioid Prescribing, Consumption, Pain, and Outcomes after Surgery Open
Objective: The aim is to compare opioid prescription, consumption, and patient-reported and clinical outcomes after surgical discharge pre- versus post-COVID-19 pandemic. Background: Numerous studies have demonstrated negative health outco…
View article: Association Between Opioid Use Disorder and Healthcare Spending and Utilization in Emergency Surgical Patients: A Retrospective Analysis Using Commercial Claims
Association Between Opioid Use Disorder and Healthcare Spending and Utilization in Emergency Surgical Patients: A Retrospective Analysis Using Commercial Claims Open
Objective: To estimate the association between opioid use disorder (OUD) and healthcare spending and utilization in emergency surgical patients, and to evaluate whether the use of opioid agonist treatment (OAT) modifies this relationship. …
View article: Comparing Analgesic Regimen Effectiveness and Safety after Surgery (CARES): protocol for a pragmatic, international multicentre randomised trial
Comparing Analgesic Regimen Effectiveness and Safety after Surgery (CARES): protocol for a pragmatic, international multicentre randomised trial Open
Introduction Acute pain is commonly experienced by millions of patients who undergo outpatient surgical procedures. Moreover, an increasing number of procedures are performed on an outpatient basis, requiring greater postoperative planning…
View article: Can theory-driven implementation interventions help clinician champions promote opioid stewardship after childbirth? Protocol for a pragmatic implementation study
Can theory-driven implementation interventions help clinician champions promote opioid stewardship after childbirth? Protocol for a pragmatic implementation study Open
Background Our objective is to determine the effect of a new national clinical practice guideline (CPG) for pain management after childbirth, as implemented with less vs. more intensive implementation support, on postpartum opioid prescrib…
View article: Impact of preoperative opioid exposure on cost of care and workplace productivity loss after elective surgery
Impact of preoperative opioid exposure on cost of care and workplace productivity loss after elective surgery Open
Introduction A high proportion of surgical patients has previous opioid exposure, which is associated with poorer recovery and increased morbidity. However, much less is known regarding the direct and indirect costs that are associated wit…
View article: Opioid consumption in the first 30 days after surgery was independently associated with new persistent opioid use
Opioid consumption in the first 30 days after surgery was independently associated with new persistent opioid use Open
Introduction Previous studies suggest that new persistent opioid use (NPOU) after surgery was associated with larger perioperative opioid prescriptions, but the association between NPOU and postoperative opioid consumption is unknown. Meth…
View article: Postoperative Opioid Consumption After Discharge: An Update From the Michigan Surgical Quality Collaborative Registry
Postoperative Opioid Consumption After Discharge: An Update From the Michigan Surgical Quality Collaborative Registry Open
Objective: To evaluate opioid consumption for 21 procedures over 4 years from the Michigan Surgical Quality Collaborative (MSQC) registry and update post-discharge prescribing guidelines. Background: Opioids remain a common treatment for p…
View article: Frailty Status, Not Just Age, is Associated With Postoperative Opioid Consumption: A Retrospective, Population-based Analysis
Frailty Status, Not Just Age, is Associated With Postoperative Opioid Consumption: A Retrospective, Population-based Analysis Open
Objective: To assess the relationship between postoperative opioid consumption and frailty status. Background: Physiologic reserve can be assessed through both chronologic age as well as measures of frailty. Although prior studies suggest …
View article: Support for Expanding Access to Cannabis Among Physicians and Adults With Chronic Pain
Support for Expanding Access to Cannabis Among Physicians and Adults With Chronic Pain Open
This survey study reports opinions of patients with chronic pain and physicians who treat chronic pain on policies regarding access to cannabis for chronic pain management.
View article: Trends in Opioid Prescribing and New Persistent Opioid Use After Surgery in the United States
Trends in Opioid Prescribing and New Persistent Opioid Use After Surgery in the United States Open
Objective: To define recent trends in opioid prescribing after surgery and new persistent opioid use in the United States. Background: New persistent opioid use after surgery among opioid-naive individuals has emerged as an important posto…
View article: Epidemiology of Opioid Prescribing After Discharge From Surgical Procedures Among Adults
Epidemiology of Opioid Prescribing After Discharge From Surgical Procedures Among Adults Open
Importance Opioid medications are commonly prescribed for the management of acute postoperative pain. In light of increasing awareness of the potential risks of opioid prescribing, data are needed to define the procedures and populations f…
View article: Access to care for patients with chronic pain receiving prescription opioids, cannabis, or other treatments
Access to care for patients with chronic pain receiving prescription opioids, cannabis, or other treatments Open
Changes in chronic noncancer pain treatment have led to decreases in prescribing of opioids and increases in the availability of medical cannabis, despite its federal prohibition. Patients may face barriers to establishing new care with a …
View article: Worth the Risk? Standardized Screening to Identify Substance Use Among Patients Before Surgery
Worth the Risk? Standardized Screening to Identify Substance Use Among Patients Before Surgery Open
Objective: We sought to compare the identification of unhealthy substance use before surgery using Tobacco, Alcohol, Prescription medication, and other Substance use (TAPS), a standardized 4-item instrument, versus routine clinical documen…
View article: Buprenorphine Dispensing after Elimination of the Waiver Requirement
Buprenorphine Dispensing after Elimination of the Waiver Requirement Open
View article: Prevalence of Surgery Among Individuals in the United States
Prevalence of Surgery Among Individuals in the United States Open
INTRODUCTION Surgery represents an important event in the lives of many patients, their families, and communities. Surgical health care expenditures represent a rising cost, accounting for more than one-quarter of all healthcare-associated…
View article: The Association of Preoperative Opioid Use with Postdischarge Outcomes
The Association of Preoperative Opioid Use with Postdischarge Outcomes Open
Objective: To examine the association of prescription opioid fills over the year before surgery with postoperative outcomes. Background: Nearly one-third of patients report opioid use in the year preceding surgery, yet an understanding of …
View article: Opioid Consumption After Discharge From Total Knee and Hip Arthroplasty: A Systematic Review and Meta-Analysis
Opioid Consumption After Discharge From Total Knee and Hip Arthroplasty: A Systematic Review and Meta-Analysis Open
Opioid prescribing exceeds the amount consumed following TKA and THA. These findings serve as a call to action to tailor prescribing guidelines to how much patients actually consume while emphasizing the use of nonopioid medications to bet…
View article: Perioperative Opioid-Related Harms: Opportunities to Minimize Risk
Perioperative Opioid-Related Harms: Opportunities to Minimize Risk Open
Although substantial attention has been given to opioid prescribing in the United States, opioid-related mortality continues to climb due to the rising incidence and prevalence of opioid use disorder. Perioperative care has an important ro…
View article: Variation in Intraoperative Opioid Administration by Patient, Clinician, and Hospital Contribution
Variation in Intraoperative Opioid Administration by Patient, Clinician, and Hospital Contribution Open
Importance The opioid crisis has led to scrutiny of opioid exposures before and after surgical procedures. However, the extent of intraoperative opioid variation and the sources and contributing factors associated with it are unclear. Obje…
View article: 919 Retrospective analysis of opioid prescribing following obstetric procedures in patients with and without opioid exposure
919 Retrospective analysis of opioid prescribing following obstetric procedures in patients with and without opioid exposure Open
View article: 920 Retrospective analysis of opioid prescribing following surgical procedures in patients with commercial vs. public insurance
920 Retrospective analysis of opioid prescribing following surgical procedures in patients with commercial vs. public insurance Open
View article: 702 Pain Management After Vaginal Birth: A Systematic Review To Support Clinical Practice Guideline Development
702 Pain Management After Vaginal Birth: A Systematic Review To Support Clinical Practice Guideline Development Open
View article: Opioid Prescribing by US Surgeons, 2016-2022
Opioid Prescribing by US Surgeons, 2016-2022 Open
This cross-sectional study investigates the rate and dosing of opioid prescriptions among US surgeons from 2016 to 2022.
View article: Perioperative opioid prescribing and iatrogenic opioid use disorder and overdose: a state-of-the-art narrative review
Perioperative opioid prescribing and iatrogenic opioid use disorder and overdose: a state-of-the-art narrative review Open
Background/importance Considerable attention has been paid to identifying and mitigating perioperative opioid-related harms. However, rates of postsurgical opioid use disorder (OUD) and overdose, along with associated risk factors, have no…
View article: Association of cannabis use with patient-reported pain measures among adults with chronic pain in US states with medical cannabis programs
Association of cannabis use with patient-reported pain measures among adults with chronic pain in US states with medical cannabis programs Open
Introduction Most Americans live in a state that has legalized cannabis as a medical treatment for pain, but it is unclear how chronic pain intensity relates to cannabis use. Our objective was to examine the association between patient-rep…
View article: Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses
Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses Open
Background Postsurgical pain is a key component of surgical recovery. However, the genetic drivers of postsurgical pain remain unclear. A broad review and meta-analyses of variants of interest will help investigators understand the potenti…