Mark Cannon
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View article: Analysis of Osmotic Pump-Administered Xylitol in a Syngeneic Mouse Melanoma Model
Analysis of Osmotic Pump-Administered Xylitol in a Syngeneic Mouse Melanoma Model Open
The present study used a syngeneic mouse model of malignant melanoma to evaluate the inhibitory efficacy of continuous xylitol administration via a subcutaneous osmotic minipump. The B16F10 syngeneic model for malignant melanoma consisted …
View article: Deep learning adaptive Model Predictive Control of Fed-Batch Cultivations
Deep learning adaptive Model Predictive Control of Fed-Batch Cultivations Open
View article: Analysis of Osmotic Pump-Administered Xylitol in a Syngeneic Mouse Melanoma Model
Analysis of Osmotic Pump-Administered Xylitol in a Syngeneic Mouse Melanoma Model Open
This study aimed to evaluate the effects of continuous xylitol administration via a subcutaneous osmotic minipump in a B16F10 syngeneic mouse model, including histological examination and metabolomic analysis. The B16F10 syngeneic model fo…
View article: Learning-based Homothetic Tube MPC
Learning-based Homothetic Tube MPC Open
In this paper, we study homothetic tube model predictive control (MPC) of discrete-time linear systems subject to bounded additive disturbance and mixed constraints on the state and input. Different from most existing work on robust MPC, w…
View article: Deep Learning Model Predictive Control for Deep Brain Stimulation in Parkinson's Disease
Deep Learning Model Predictive Control for Deep Brain Stimulation in Parkinson's Disease Open
We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses th…
View article: Editorial: Special Issue on Model Predictive Control Under Disturbances and Uncertainties: Safety, Stability, and Learning
Editorial: Special Issue on Model Predictive Control Under Disturbances and Uncertainties: Safety, Stability, and Learning Open
View article: Deep learning adaptive Model Predictive Control of Fed-Batch Cultivations
Deep learning adaptive Model Predictive Control of Fed-Batch Cultivations Open
Bioprocesses are often characterised by nonlinear and uncertain dynamics, posing particular challenges for model predictive control (MPC) algorithms due to their computational demands when applied to nonlinear systems. Recent advances in o…
View article: Safe adaptive NMPC using ellipsoidal tubes
Safe adaptive NMPC using ellipsoidal tubes Open
A computationally efficient nonlinear Model Predictive Control (NMPC) algorithm is proposed for safe learning-based control with a system model represented by an incompletely known affine combination of basis functions and subject to addit…
View article: Robust targeted exploration for systems with non-stochastic disturbances
Robust targeted exploration for systems with non-stochastic disturbances Open
In this paper, we introduce a novel targeted exploration strategy designed specifically for uncertain linear time-invariant systems with energy-bounded disturbances, i.e., without making any assumptions on the distribution of the disturban…
View article: Cancer Cell Line Inhibition by Osmotic Pump-administered Xylitol in a Syngeneic Mouse Model
Cancer Cell Line Inhibition by Osmotic Pump-administered Xylitol in a Syngeneic Mouse Model Open
View article: Towards targeted exploration for non-stochastic disturbances
Towards targeted exploration for non-stochastic disturbances Open
View article: Towards targeted exploration for non-stochastic disturbances
Towards targeted exploration for non-stochastic disturbances Open
We present a novel targeted exploration strategy for linear time-invariant systems without stochastic assumptions on the noise, i.e., without requiring independence or zero mean, allowing for deterministic model misspecifications. This wor…
View article: Guest Editorial Special Issue on State-of-the-Art Applications of Model Predictive Control
Guest Editorial Special Issue on State-of-the-Art Applications of Model Predictive Control Open
Advancements in computing hardware and refinements of numerical solvers for convex optimization problems have prompted a burst of interest in the utilization of model predictive control (MPC) to a myriad of challenging control problems and…
View article: Data-driven robust MPC of tiltwing VTOL aircraft
Data-driven robust MPC of tiltwing VTOL aircraft Open
This paper investigates robust tube-based Model Predictive Control (MPC) of a tiltwing Vertical Take-Off and Landing (VTOL) aircraft subject to wind disturbances and model uncertainty. Our approach is based on a Difference of Convex (DC) f…
View article: Learning-based Rigid Tube Model Predictive Control
Learning-based Rigid Tube Model Predictive Control Open
This paper is concerned with model predictive control (MPC) of discrete-time linear systems subject to bounded additive disturbance and mixed constraints on the state and input, whereas the true disturbance set is unknown. Unlike most exis…
View article: Data from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Data from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Kaposi's sarcoma (KS) is caused by Kaposi's sarcoma–associated herpesvirus (KSHV) and consists of proliferating spindle cells, which are related to lymphatic endothelial cells (LEC). Angiopoietin-2 (Ang2) is a secreted proangiogenic and ly…
View article: Supplementary Figure Legend from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2
Supplementary Figure Legend from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2 Open
PDF file - 32K
View article: Supplementary Figure 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Figure 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Figure 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Data from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2
Data from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2 Open
EZH2 is a component of the epigenetic regulator PRC2 that suppresses gene expression. Elevated expression of EZH2 is common in human cancers and is associated with tumor progression and poor prognosis. In this study, we show that EZH2 elev…
View article: Supplementary Methods and Materials from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Methods and Materials from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Methods and Materials from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Supplementary Figure Legends 1-3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Figure Legends 1-3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Figure Legends 1-3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Supplementary Figure 1 from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2
Supplementary Figure 1 from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2 Open
PDF file - 101K, KSHV infection converts BOEC cells into spindle shape, and upregulates the expression of lymphatic endothelial markers
View article: Supplementary Figure 2 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Figure 2 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Figure 2 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Data from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2
Data from Cancer Angiogenesis Induced by Kaposi Sarcoma–Associated Herpesvirus Is Mediated by EZH2 Open
EZH2 is a component of the epigenetic regulator PRC2 that suppresses gene expression. Elevated expression of EZH2 is common in human cancers and is associated with tumor progression and poor prognosis. In this study, we show that EZH2 elev…
View article: Supplementary Figure 2 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Figure 2 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Figure 2 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Supplementary Figure 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Figure 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Figure 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Supplementary Table 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Table 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Table 1 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Data from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Data from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Kaposi's sarcoma (KS) is caused by Kaposi's sarcoma–associated herpesvirus (KSHV) and consists of proliferating spindle cells, which are related to lymphatic endothelial cells (LEC). Angiopoietin-2 (Ang2) is a secreted proangiogenic and ly…
View article: Supplementary Figure 3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Figure 3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Figure 3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
View article: Supplementary Figure 3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells
Supplementary Figure 3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells Open
Supplementary Figure 3 from Kaposi's Sarcoma–Associated Herpesvirus-Encoded Interleukin-6 and G-Protein–Coupled Receptor Regulate Angiopoietin-2 Expression in Lymphatic Endothelial Cells