Mark E. Stanton
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View article: Lorazepam-induced amnesia : examination of delayed free recall and priming effects
Lorazepam-induced amnesia : examination of delayed free recall and priming effects Open
Benzodiazepines are a class of drugs that produce a number of side effects including temporary memory impairments which appear to parallel organic amnesia. This raises the possibility that benzodiazepines can be utilised as another method …
View article: Disruption of cerebellar maturation by an antimitotic agent impairs the ontogeny of eyeblink conditioning in rats
Disruption of cerebellar maturation by an antimitotic agent impairs the ontogeny of eyeblink conditioning in rats Open
This study represents an attempt to establish a relationship between maturation of the cerebellum and the ontogeny of eyeblink conditioning in the rat. Experiments 1 and 2 examined the effects of disrupting cerebellar maturation by neonata…
View article: NMDA receptors and the ontogeny of post‐shock and retention freezing during contextual fear conditioning
NMDA receptors and the ontogeny of post‐shock and retention freezing during contextual fear conditioning Open
The ontogeny and NMDA‐receptor (NMDAR) mechanisms of context conditioning were examined during standard contextual fear conditioning (sCFC) – involving context and context‐shock learning in the same trial – as a comparison with our previou…
View article: Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial
Efficacy of Maternal Choline Supplementation During Pregnancy in Mitigating Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Function: A Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial Open
Background We recently demonstrated the acceptability and feasibility of a randomized, double‐blind choline supplementation intervention for heavy drinking women during pregnancy. In this study, we report our results relating to the effica…
View article: Differential involvement of the medial prefrontal cortex across variants of contextual fear conditioning
Differential involvement of the medial prefrontal cortex across variants of contextual fear conditioning Open
The context preexposure facilitation effect (CPFE) is a contextual fear conditioning paradigm in which learning about the context, acquiring the context-shock association, and retrieving/expressing contextual fear are temporally dissociate…
View article: White matter deficits mediate effects of prenatal alcohol exposure on cognitive development in childhood
White matter deficits mediate effects of prenatal alcohol exposure on cognitive development in childhood Open
Fetal alcohol spectrum disorders comprise the spectrum of cognitive, behavioral, and neurological impairments caused by prenatal alcohol exposure (PAE). Diffusion tensor imaging (DTI) was performed on 54 children (age 10.1 ± 1.0 years) fro…
View article: Cholinergic mechanisms of the context preexposure facilitation effect in adolescent rats.
Cholinergic mechanisms of the context preexposure facilitation effect in adolescent rats. Open
The context preexposure facilitation effect (CPFE) is a variant of contextual fear conditioning in which context learning, context-shock association, and expression of context conditioning occur in 3 separate phases-preexposure, training, …
View article: Eyeblink Classical Conditioning in Alcoholism and Fetal Alcohol Spectrum Disorders
Eyeblink Classical Conditioning in Alcoholism and Fetal Alcohol Spectrum Disorders Open
Alcoholism is a debilitating disorder that can take a significant toll on health and professional and personal relationships. Excessive alcohol consumption can have a serious impact on both drinkers and developing fetuses, leading to long-…
View article: White matter integrity of the cerebellar peduncles as a mediator of effects of prenatal alcohol exposure on eyeblink conditioning
White matter integrity of the cerebellar peduncles as a mediator of effects of prenatal alcohol exposure on eyeblink conditioning Open
Fetal alcohol spectrum disorders (FASD) are characterized by a range of neurodevelopmental deficits that result from prenatal exposure to alcohol. These can include cognitive, behavioural, and neurological impairment, as well as structural…