Mark Ellrichmann
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View article: European Consensus Recommendations for Direct Cholangioscopy and Pancreatoscopy Using a Modified Delphi Process
European Consensus Recommendations for Direct Cholangioscopy and Pancreatoscopy Using a Modified Delphi Process Open
Background and Aim Direct cholangioscopy and pancreatoscopy have become widely implemented techniques in the diagnostic and therapeutic algorithms of several pancreaticobiliary disorders. This study aimed to generate general and indication…
View article: Oral Microcapsule Chromocolonoscopy With Patent Blue V Improves Adenoma Detection Safely and Effectively
Oral Microcapsule Chromocolonoscopy With Patent Blue V Improves Adenoma Detection Safely and Effectively Open
Background and Objective Chromocolonoscopy significantly improves polyp/adenoma detection rates (PDR/ADR). However, its integration into routine clinical practice is hindered by its cumbersome mode of application. The objective was to deve…
View article: Long‐Term Efficacy and Safety of Digital‐Single‐Operator‐Video‐Pancreatoscopy Guided Lithotripsy for Pancreatic Duct Stones
Long‐Term Efficacy and Safety of Digital‐Single‐Operator‐Video‐Pancreatoscopy Guided Lithotripsy for Pancreatic Duct Stones Open
Introduction Ductal decompression has become the main approach for treating patients with symptomatic chronic calcifying pancreatitis and signs of ductal hypertension. Digital single operator video pancreatoscopy (dSOVP) has shown high suc…
View article: The value of cholangioscopy-guided bite-on-bite (-on bite) biopsies in indeterminate biliary duct strictures
The value of cholangioscopy-guided bite-on-bite (-on bite) biopsies in indeterminate biliary duct strictures Open
Background Digital single-operator cholangioscopy (dSOC) has improved the diagnostic accuracy of indeterminate biliary duct strictures (IBDS) through targeted intraductal biopsy sampling. However, the optimal biopsy technique remains uncer…
View article: Endoscopic Management of Biliary Leakages
Endoscopic Management of Biliary Leakages Open
Background: Biliary leakages are notable complications that can occur following hepatobiliary surgery, traumatic injury, or iatrogenic causes related to medical interventions. The management of biliary leaks is critical as untreated leaks …
View article: Endoscopic Treatment of Anastomotic Leakage in the Upper Gastrointestinal Tract
Endoscopic Treatment of Anastomotic Leakage in the Upper Gastrointestinal Tract Open
Background: Anastomotic leakage (AL) in the upper gastrointestinal tract (uGIT) is a critical condition associated with high mortality and significant morbidity. Effective management requires prompt and specialized diagnostic and therapeut…
View article: Diagnostic work-up of bile duct strictures: European Society of Gastrointestinal Endoscopy (ESGE) Guideline
Diagnostic work-up of bile duct strictures: European Society of Gastrointestinal Endoscopy (ESGE) Guideline Open
Main recommendations 1 ESGE recommends the combination of endoscopic ultrasound-guided tissue acquisition (EUS-TA) and endoscopic retrograde cholangiopancreatography (ERCP)-based tissue acquisition as the preferred diagnostic approach for …
View article: Efficacy of Racecadotril in a Patient Affected by a Therapy-Refractory VIPoma and Carcinoid Syndrome
Efficacy of Racecadotril in a Patient Affected by a Therapy-Refractory VIPoma and Carcinoid Syndrome Open
Neuroendocrine neoplasms (NENs) encompass a heterogeneous spectrum of tumors originating from the diffuse neuroendocrine cell system. Approximately 30% of NEN exhibit functional activity with clinical syndromes through hormone-mediated eff…
View article: Endoluminal Vacuum Therapy Using a New “Fistula Sponge” in Treating Defects of the Upper Gastrointestinal Tract—A Comparative, Retrospective Cohort Study
Endoluminal Vacuum Therapy Using a New “Fistula Sponge” in Treating Defects of the Upper Gastrointestinal Tract—A Comparative, Retrospective Cohort Study Open
Background and Objectives: Anastomotic insufficiencies (AI) and perforations of the upper gastrointestinal tract (uGIT) result in high morbidity and mortality. Endoscopic stent placement and endoluminal vacuum therapy (EVT) have been estab…
View article: Contrast-Enhanced Endoscopic Ultrasound Detects Early Therapy Response Following Anti-TNF Therapy in Patients with Ulcerative Colitis
Contrast-Enhanced Endoscopic Ultrasound Detects Early Therapy Response Following Anti-TNF Therapy in Patients with Ulcerative Colitis Open
Background and Aims Though colonoscopy plays a crucial role in assessing active ulcerative colitis [aUC], its scope is limited to the mucosal surface. Endoscopic ultrasound [EUS] coupled with contrast-enhancement [dCEUS] can precisely quan…
View article: High-resolution rectoscopy using MHz optical coherence tomography: a step towards real time 3D endoscopy
High-resolution rectoscopy using MHz optical coherence tomography: a step towards real time 3D endoscopy Open
Colonoscopy and endoscopic ultrasound play pivotal roles in the assessment of rectal diseases, especially rectal cancer and inflammatory bowel diseases. Optical coherence tomography (OCT) offers a superior depth resolution, which is a crit…
View article: Endoluminal vacuum therapy using a new “fistula sponge” in treating defects of the upper gastrointestinal tract – a comparative, retrospective cohort study.
Endoluminal vacuum therapy using a new “fistula sponge” in treating defects of the upper gastrointestinal tract – a comparative, retrospective cohort study. Open
Background: Anastomotic insufficiencies (AI) and perforations of the upper gastrointestinal tract (uGIT) result in high morbidity and mortality. As treatment options surgical revision, endoscopic stent placement as well as endoluminal vacu…
View article: Virtual Hall sensor triggered multi-MHz endoscopic OCT imaging for stable real-time visualization
Virtual Hall sensor triggered multi-MHz endoscopic OCT imaging for stable real-time visualization Open
Circumferential scanning in endoscopic imaging is crucial across various disciplines, and optical coherence tomography (OCT) is often the preferred choice due to its high-speed, high-resolution, and micron-scale imaging capabilities. Moreo…
View article: Liver transplantation for HCC in cirrhosis: Are Milan criteria outdated?
Liver transplantation for HCC in cirrhosis: Are Milan criteria outdated? Open
In Germany, organ allocation is based on the MELD-system and lab-MELD is usually low in patients with hepatocellular carcinoma (HCC) in cirrhosis. Higher medical urgency can be achieved by standard exception for HCC (SE-HCC), if Milan crit…
View article: PERcutaneous transhepatic CHOLangioscopy using a new single‐operator short cholangioscope (PERCHOL): European feasibility study
PERcutaneous transhepatic CHOLangioscopy using a new single‐operator short cholangioscope (PERCHOL): European feasibility study Open
Objectives A new short device for percutaneous endoscopic cholangioscopy was recently developed. However, feasibility and safety has not yet been evaluated. The aim of this study was to assess clinical success, technical success, and adver…
View article: Clinical implantation of 92 VACStents in the upper gastrointestinal tract of 50 patients—applicability and safety analysis of an innovative endoscopic concept
Clinical implantation of 92 VACStents in the upper gastrointestinal tract of 50 patients—applicability and safety analysis of an innovative endoscopic concept Open
Introduction Endoscopic vacuum therapy (EVT) has emerged as a promising treatment option for upper gastrointestinal wall defects, offering benefits such as evacuation of secretions and removal of wound debris by suction, and reduction and …
View article: Stent placement in pancreatic disease, when, which and why? – a current perspective
Stent placement in pancreatic disease, when, which and why? – a current perspective Open
Introduction Stenting of the pancreas is a challenging task for the interventional gastroenterologist. The indications for pancreatic stent implantation are either prophylactic or therapeutic. We give an overview of currently available lit…
View article: Digital single-operator pancreatoscopy for the treatment of symptomatic pancreatic duct stones: a prospective multicenter cohort trial
Digital single-operator pancreatoscopy for the treatment of symptomatic pancreatic duct stones: a prospective multicenter cohort trial Open
Background Digital single-operator pancreatoscopy (DSOP)-guided lithotripsy is a novel treatment modality for pancreatic endotherapy, with demonstrated technical success in retrospective series of between 88 % and 100 %. The aim of this pr…
View article: The role of pancreatoscopy in the diagnostic work-up of intraductal papillary mucinous neoplasms: a systematic review and meta-analysis
The role of pancreatoscopy in the diagnostic work-up of intraductal papillary mucinous neoplasms: a systematic review and meta-analysis Open
Background Confirming the diagnosis, invasiveness, and disease extent of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas is challenging. The aim of this study was to summarize the literature on the efficacy and safety of p…
View article: Eso-Sponge® for anastomotic leakage after oesophageal resection or perforation: outcomes from a national, prospective multicentre registry
Eso-Sponge® for anastomotic leakage after oesophageal resection or perforation: outcomes from a national, prospective multicentre registry Open
Background Anastomotic leakage (AL) after oesophagectomy and oesophageal perforations are associated with significant morbidity and mortality. Minimally invasive endoscopy is often used as first-line treatment, particularly endoluminal vac…
View article: Clinical practice patterns in indirect peroral cholangiopancreatoscopy: outcome of a European survey
Clinical practice patterns in indirect peroral cholangiopancreatoscopy: outcome of a European survey Open
Background and aims Indirect peroral cholangiopancreatoscopy (IPOC) is a relatively new diagnostic and therapeutic tool for biliopancreatic diseases. This international survey aimed to evaluate clinical practice patterns in IPOC among endo…
View article: Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome Open
Objective A considerable proportion of patients with irritable bowel syndrome (IBS) may be wheat-sensitive and respond to a gluten-free diet (GFD) although they do not have coeliac disease. However, a diagnostic test for wheat sensitivity …
View article: Imaging Inflammation – From Whole Body Imaging to Cellular Resolution
Imaging Inflammation – From Whole Body Imaging to Cellular Resolution Open
Imaging techniques have evolved impressively lately, allowing whole new concepts like multimodal imaging, personal medicine, theranostic therapies, and molecular imaging to increase general awareness of possiblities of imaging to medicine …
View article: Subclinical Pulmonary Involvement in Active IBD Responds to Biologic Therapy
Subclinical Pulmonary Involvement in Active IBD Responds to Biologic Therapy Open
Objective Increased mortality from respiratory diseases was observed in epidemiological studies of patients with ulcerative colitis [UC] as a potentially underestimated extraintestinal manifestation. We therefore investigated the presence …
View article: Magnetic bead-assisted endoscopic submucosal dissection: a gravity-based traction method for treating large superficial colorectal tumors
Magnetic bead-assisted endoscopic submucosal dissection: a gravity-based traction method for treating large superficial colorectal tumors Open
MBA-ESD is a feasible, safe, and effective method for treating large superficial colorectal tumors. Further large, prospective and controlled studies are needed to fully assess this method.
View article: Advanced endoscopic submucosal dissection with magnetic bead-assisted traction based on gravity for a flat colorectal neoplasm with severe fibrosis
Advanced endoscopic submucosal dissection with magnetic bead-assisted traction based on gravity for a flat colorectal neoplasm with severe fibrosis Open
Endoscopic submucosal dissection (ESD) of colorectal lesions with severe submucosal fibrosis remains challenging. Fibrosis has also been implicated as a factor that increases the risk of incomplete or complicated dissection [1] [2] [3]. Se…
View article: Long-term quality of life after endovac-therapy in anastomotic leakages after esophagectomy
Long-term quality of life after endovac-therapy in anastomotic leakages after esophagectomy Open
Endoluminal vacuum therapy (EVT) has been successfully established with promising survival rates in the treatment of anastomotic leakages after esophagectomy. It is still unclear how this therapy affects health related quality of life (HRQ…
View article: Combination therapy with vedolizumab and etanercept in a patient with pouchitis and spondylarthritis
Combination therapy with vedolizumab and etanercept in a patient with pouchitis and spondylarthritis Open
Inflammatory bowel disease is frequently associated with spondylarthritis (SpA). It has been discussed that α4/β7 expressing lymphocytes are involved in the aetiology of SpA. We report a case of a successful combination therapy of vedolizu…