A. Mark Fendrick
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View article: Supplementary Table S1 from Reallocating Cervical Cancer Preventive Service Spending from Low- to High-Value Clinical Scenarios
Supplementary Table S1 from Reallocating Cervical Cancer Preventive Service Spending from Low- to High-Value Clinical Scenarios Open
Supplementary Table S1 includes codes used to identify cervical cancer screening tests within claims data.
View article: Supplementary Table S3 from Reallocating Cervical Cancer Preventive Service Spending from Low- to High-Value Clinical Scenarios
Supplementary Table S3 from Reallocating Cervical Cancer Preventive Service Spending from Low- to High-Value Clinical Scenarios Open
Supplementary Table S3 shows CPT codes used in the analysis of colposcopy and related cervical services.
View article: The impact of multicancer early detection tests on cancer stage shift: A 10‐year microsimulation model
The impact of multicancer early detection tests on cancer stage shift: A 10‐year microsimulation model Open
Introduction Early detection of cancer improves survival following diagnosis. However, routine screening is limited to a few cancer types. Multicancer early detection (MCED) tests could revolutionize cancer screening by simultaneously dete…
View article: Supplementary Table 5 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States
Supplementary Table 5 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States Open
Supplementary Table 5: Sensitivity of MCED by Cancer Type and Stage
View article: Supplementary Table 4 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States
Supplementary Table 4 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States Open
Supplementary Table 4: Weighted IRRs for Overall HCS Population and Gene Mutation Groupings by Cancer Type
View article: Supplementary Table 3 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States
Supplementary Table 3 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States Open
Supplementary Table 3: Cancer Risk by Gene Mutations and The Associated Risk of Cancer in The General Population
View article: Supplementary Table 2 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States
Supplementary Table 2 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States Open
Supplementary Table 2: Incidence Rate Ratios for Cancer Survivor by Age Group vs. the General Population by Cancer Type
View article: Supplementary Table 1 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States
Supplementary Table 1 from Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States Open
Supplementary Table 1: Cancer Survivor Mortality Hazard Ratios
View article: High Adherence to Repeat Multitarget Stool DNA Testing and Follow-Up Colonoscopy in Average-Risk United States Adults: Results from a Nationally Insured Cohort
High Adherence to Repeat Multitarget Stool DNA Testing and Follow-Up Colonoscopy in Average-Risk United States Adults: Results from a Nationally Insured Cohort Open
The mt-sDNA test was associated with high repeat screening adherence (86.1%) and a follow-up colonoscopy rate of 76.0%, with mt-sDNA adherence exceeding 80% in most subgroups. These findings support its utility as a reliable, home-based CR…
View article: Kennedy v. Braidwood and Weight Management Preventive Services: A Renewed Opportunity for Improved Health
Kennedy v. Braidwood and Weight Management Preventive Services: A Renewed Opportunity for Improved Health Open
View article: Evaluating benefit-to-burden ratios of the established and emerging colorectal cancer screening strategies
Evaluating benefit-to-burden ratios of the established and emerging colorectal cancer screening strategies Open
Background Recommended noninvasive strategies for average-risk colorectal cancer (CRC) screening include multitarget stool DNA and fecal immunochemical test from ages 45 to 75 years. With new clinical trials, performance data for next-gene…
View article: Measure Twice, Implement Once: There Is a Need to Deliberately Consider All Aspects of Artificial Intelligence-Assisted Messaging
Measure Twice, Implement Once: There Is a Need to Deliberately Consider All Aspects of Artificial Intelligence-Assisted Messaging Open
View article: Comparison of Benefit-to-Burden Ratios for Stool-Based Colorectal Cancer Screening Tests in the U.S.: A Decision Analytical Modeling Approach
Comparison of Benefit-to-Burden Ratios for Stool-Based Colorectal Cancer Screening Tests in the U.S.: A Decision Analytical Modeling Approach Open
View article: Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States
Impact of Population Cancer Risk on the Cost-effectiveness of Multicancer Early Detection Testing in the United States Open
Background: Cancer remains a significant global health challenge, particularly for subpopulations with risk factors including genetic predisposition, comorbidities, and lifestyle, along with age. The Galleri multicancer early detection (MC…
View article: Adherence to Multitarget Stool DNA Testing in Individuals Aged 45–49 Years With Average Risk for Colorectal Cancer
Adherence to Multitarget Stool DNA Testing in Individuals Aged 45–49 Years With Average Risk for Colorectal Cancer Open
INTRODUCTION: Recommendations for colorectal cancer (CRC) screening have been updated to include individuals aged 45–49 years, addressing recent increases in CRC rates among young adults. The multitarget stool DNA (mt-sDNA) test is approve…
View article: The Consequences of the <i>Kennedy v. Braidwood</i> Supreme Court Ruling on Fall Prevention
The Consequences of the <i>Kennedy v. Braidwood</i> Supreme Court Ruling on Fall Prevention Open
View article: Multi-Target Stool DNA and the Fecal Immunochemical Test: A Systematic Review and Meta-Analysis on Test Performances
Multi-Target Stool DNA and the Fecal Immunochemical Test: A Systematic Review and Meta-Analysis on Test Performances Open
View article: Fiscal Impact of Expanded Medicare Coverage for GLP-1 Receptor Agonists to Treat Obesity
Fiscal Impact of Expanded Medicare Coverage for GLP-1 Receptor Agonists to Treat Obesity Open
Importance Despite the clinical benefits of treating obesity and related complications, glucagon-like peptide-1 receptor agonists (GLP-1RAs) are not yet covered by Medicare Part D, partly due to high drug costs. The Biden administration’s …
View article: Brand-to-brand nonmedical switching among interleukin-17 inhibitors or other biologics: Implications of a formulary change
Brand-to-brand nonmedical switching among interleukin-17 inhibitors or other biologics: Implications of a formulary change Open
Following the formulary change, more than 25% of patients exposed to the change experienced treatment discontinuation, nearly double the rate than those not exposed. This unfavorable finding, along with higher rates of nonadherence and sub…
View article: Correction to: Adherence to multi‑target stool DNA testing for colorectal cancer screening in the United States
Correction to: Adherence to multi‑target stool DNA testing for colorectal cancer screening in the United States Open
View article: Projected Out-of-Pocket Savings of the Medicare Part D $2 Drug List Model
Projected Out-of-Pocket Savings of the Medicare Part D $2 Drug List Model Open
This study evaluates the amount of out-of-pocket cost savings Medicare Part D beneficiaries would have experienced if a proposed Medicare $2 drug list model had been in place in 2021.
View article: Association Between Out-of-Pocket Insurance Costs and Psychotherapy Utilization Among Commercially Insured Birthing Individuals
Association Between Out-of-Pocket Insurance Costs and Psychotherapy Utilization Among Commercially Insured Birthing Individuals Open
View article: Environmental impact of colorectal cancer screening with colonoscopy and multi-target stool DNA (mt-sDNA) testing
Environmental impact of colorectal cancer screening with colonoscopy and multi-target stool DNA (mt-sDNA) testing Open
The substantial carbon footprint imparted by medical services warrants increased attention to their environmental impact. National guideline organizations such as the US Preventive Services Task Force (USPSTF) recommend multiple modalities…
View article: Re-screening adherence to multi-target stool DNA test for colorectal cancer: real-world study in a large national population
Re-screening adherence to multi-target stool DNA test for colorectal cancer: real-world study in a large national population Open
View article: Real-World Adherence to Multi-Target Stool DNA Testing for Colorectal Cancer Among Asian Americans
Real-World Adherence to Multi-Target Stool DNA Testing for Colorectal Cancer Among Asian Americans Open
Introduction: Asian Americans have lower colorectal cancer (CRC) screening rates compared to other racial/ethnic groups. Given the importance of early detection and subsequent treatment in improving survival, this study examines adherence …
View article: Trends in antipsychotic prescribing among community-dwelling older adults with dementia, 2010-2018
Trends in antipsychotic prescribing among community-dwelling older adults with dementia, 2010-2018 Open
Due to an FDA “black box” warning for heightened risk of death, Choosing Wisely (CW) recommends avoiding antipsychotic prescription drugs as first-line treatment for dementia-related agitation. Yet, post-CW trends among community-dwelling …
View article: Adherence to multi-target stool DNA testing for colorectal cancer screening in the United States
Adherence to multi-target stool DNA testing for colorectal cancer screening in the United States Open
View article: The Potential Impact of the Kennedy v. Braidwood Supreme Court Decision on Hepatitis C Diagnosis and Treatment in the United States
The Potential Impact of the Kennedy v. Braidwood Supreme Court Decision on Hepatitis C Diagnosis and Treatment in the United States Open
View article: Overcoming Challenges to Optimize the Clinical and Financial Benefits of In-Home Rehabilitation Services
Overcoming Challenges to Optimize the Clinical and Financial Benefits of In-Home Rehabilitation Services Open
The authors advocate for the implementation of value-based principles to address the underutilization and limited supply of home care and rehabilitation services.
View article: Adherence to Follow-Up Colonoscopy After a Positive Stool-Based Test in Patients Aged 45–49 Years: Real-World Differences Between Multitarget Stool DNA Testing and Fecal Immunochemical or Fecal Occult Blood Testing
Adherence to Follow-Up Colonoscopy After a Positive Stool-Based Test in Patients Aged 45–49 Years: Real-World Differences Between Multitarget Stool DNA Testing and Fecal Immunochemical or Fecal Occult Blood Testing Open
FU-CY adherence rates were significantly higher in patients screened with mt-sDNA compared to those screened with FIT/FOBT. These results suggest that in younger patient populations, mt-sDNA may be a promising tool to improve FU-CY adheren…