Mark Fish
YOU?
Author Swipe
View article: Informant Accuracy of IQCODE, AD8 and GPCOGi for diagnosis of dementia: Does your friend know best?
Informant Accuracy of IQCODE, AD8 and GPCOGi for diagnosis of dementia: Does your friend know best? Open
Background Increasing numbers of people are requiring evaluation for possible dementia. There has been limited research exploring the accuracy of informant questionnaires in primary care. Methods A diagnostic accuracy study to explore the …
View article: Predictors and prognosis of population-based subjective cognitive decline: longitudinal evidence from the Caerphilly Prospective Study (CaPS)
Predictors and prognosis of population-based subjective cognitive decline: longitudinal evidence from the Caerphilly Prospective Study (CaPS) Open
Objectives To understand associations between the subjective experience of cognitive decline and objective cognition. This subjective experience is often conceptualised as an early step towards neurodegeneration, but this has not been scru…
View article: A Diagnostic Test Accuracy Study Investigating General Practitioner Clinical Impression and Brief Cognitive Assessments for Dementia in Primary Care, Compared to Specialized Assessment
A Diagnostic Test Accuracy Study Investigating General Practitioner Clinical Impression and Brief Cognitive Assessments for Dementia in Primary Care, Compared to Specialized Assessment Open
Background: Many health systems are interested in increasing the number of uncomplicated and typical dementia diagnoses that are made in primary care, but the comparative accuracy of tests is unknown. Objective: Calculate diagnostic accura…
View article: Clinical judgment of GPs for the diagnosis of dementia: a diagnostic test accuracy study
Clinical judgment of GPs for the diagnosis of dementia: a diagnostic test accuracy study Open
Background GPs often report using clinical judgment to diagnose dementia. Aim To investigate the accuracy of GPs’ clinical judgment for the diagnosis of dementia. Design & setting Diagnostic test accuracy study, recruiting from 21 practice…
View article: Sleep and the risk of cognitive impairment and dementia: further insights from the Caerphilly Prospective Study
Sleep and the risk of cognitive impairment and dementia: further insights from the Caerphilly Prospective Study Open
Aims Sleep disorders are highly prevalent with growing evidence that sleep problems may predict cognitive decline and dementia. A previous analysis of the Caerphilly Prospective Study (CaPS), a cohort of middle-aged men, found that daytime…
View article: Clinical judgement of General Practitioners for the diagnosis of dementia: a diagnostic test accuracy study
Clinical judgement of General Practitioners for the diagnosis of dementia: a diagnostic test accuracy study Open
Background The accuracy of General Practitioners’ (GPs’) clinical judgement for dementia is uncertain. Aim Investigate the accuracy of GPs’ clinical judgement for the diagnosis of dementia. Design and Setting Diagnostic test accuracy study…
View article: Skull base aspergillosis in an immunocompetent elderly man with early response to steroid
Skull base aspergillosis in an immunocompetent elderly man with early response to steroid Open
We report the case of a previously well 80-year-old man who presented with subacute bilateral painful optic neuropathy with initial response to corticosteroids but ultimately progressed to a fatal skull base syndrome. Initial presentation …
View article: Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis
Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis Open
Neuromuscular pathology in ALS involves the systemic regulation of inflammatory markers mostly active on T-cell immune responses. Disease stratification based on the prognostic value of circulating inflammatory markers could improve clinic…
View article: Clinical history for diagnosis of dementia in men: Caerphilly Prospective Study
Clinical history for diagnosis of dementia in men: Caerphilly Prospective Study Open
This study found that three simple questions have high utility for diagnosing dementia in men who are cognitively screened. If confirmed, this could lead to less burdensome assessment where clinical assessment suggests possible dementia.
View article: Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study
Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study Open
Motor Neurone Disease Association of Great Britain and Northern Ireland (MNDA) and the Sheffield Institute for Translational Neuroscience (SITraN).
View article: Neurofilament light chain
Neurofilament light chain Open
This report provides Class III evidence that the NfL electrochemiluminescence immunoassay accurately distinguishes patients with sporadic ALS from healthy controls.