Mark Gregory
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View article: Integration of Non-Terrestrial Network for 5G IoT and Future 6G
Integration of Non-Terrestrial Network for 5G IoT and Future 6G Open
The exponential growth of the Internet of Things (IoT) has spurred the need for robust and extensive connectivity solutions. In response to the market and use-case requirements, the Third Generation Partnership Project (3GPP) introduced Na…
View article: A Robust Eclipse Attack Detection Framework for Ethereum Networks ⋆
A Robust Eclipse Attack Detection Framework for Ethereum Networks ⋆ Open
View article: Eclipse Attacks in Blockchain Networks: Detection, Prevention, and Future Directions
Eclipse Attacks in Blockchain Networks: Detection, Prevention, and Future Directions Open
This paper presents a comprehensive study on eclipse attacks in blockchain networks by describing how eclipse attacks work, their effects, detection, and prevention. In this context, understanding and controlling network-level attacks, suc…
View article: Implementing zero trust security with dual fuzzy methodology for trust-aware authentication and task offloading in Multi-access Edge Computing
Implementing zero trust security with dual fuzzy methodology for trust-aware authentication and task offloading in Multi-access Edge Computing Open
This paper proposes an efficient trust-aware authentication and task offloading scheme for Multi-Access Edge Computing (MEC) using the Zero Trust Security (ZTS) principles. The proposed method uses a dual fuzzy logic system to evaluate the…
View article: Proactive defense mechanism: Enhancing IoT security through diversity-based moving target defense and cyber deception
Proactive defense mechanism: Enhancing IoT security through diversity-based moving target defense and cyber deception Open
The Internet of Things (IoT) has become increasingly prevalent in various aspects of our lives, enabling billions of devices to connect and communicate seamlessly. However, the intricate nature of IoT connections and device vulnerabilities…
View article: Multi-Access Edge Computing Handover Strategies, Management, and Challenges: A Review
Multi-Access Edge Computing Handover Strategies, Management, and Challenges: A Review Open
The deployment and operation of Multi-Access Edge Computing (MEC) at the network edge provides low latency computing and storage services for end user devices. Support for device mobility is a functional requirement for MEC and a handover …
View article: Multi-Access Edge Computing Resource Slice Allocation: A Review
Multi-Access Edge Computing Resource Slice Allocation: A Review Open
The global deployment of fifth generation mobile cellular (5G) and beyond (5GB) communication systems has accelerated the growth of the Internet of Things (IoT) and the Internet of Everything (IoE). New applications and services that add c…
View article: Warrnambool exchange fire consumer and social impact analysis
Warrnambool exchange fire consumer and social impact analysis Open
This report presents analyses of the far-reaching social impacts of the fire and resulting telecommunications outage in Warrnambool, a large regional town in Western Victoria, Australia. The findings have relevance to preparedness and risk…
View article: Artificial Intelligence-Defined Wireless Networking for Computational Offloading and Resource Allocation in Edge Computing Networks
Artificial Intelligence-Defined Wireless Networking for Computational Offloading and Resource Allocation in Edge Computing Networks Open
The advent of the Internet of Everything and new Ultra-Reliable Low-Latency Communication (URLLC) services has resulted in an exponential growth in data demands at the network’s edge. To meet the stringent performance requirements of evolv…
View article: Dynamic Resource Management in Control Plane Session and User Plane Over the Mec-Enabled 5g Core Network
Dynamic Resource Management in Control Plane Session and User Plane Over the Mec-Enabled 5g Core Network Open
View article: Submission to the Productivity Commission Inquiry into the Telecommunications Universal Service Obligation
Submission to the Productivity Commission Inquiry into the Telecommunications Universal Service Obligation Open
The Universal Service Obligation is a vital aspect of provision of telecommunications and the principal of universal service currently is to ensure that all people, wherever they reside or carry on business, should have reasonable access, …
View article: An Analysis of the Optus National Outage and Recommendations for Enhanced Regulation
An Analysis of the Optus National Outage and Recommendations for Enhanced Regulation Open
On Wednesday, 8 November 2023 at about 4am, approximately 10 million Optus retail and 400,000 business customers lost network access as a result of the IP Core network shutdown. Optus stated that the cause of the network outage was a routi…
View article: Explainer: what is the ‘core network’ that was crucial to the Optus outage?
Explainer: what is the ‘core network’ that was crucial to the Optus outage? Open
View article: Optus blackout explained: what is a ‘deep network’ outage and what may have caused it?
Optus blackout explained: what is a ‘deep network’ outage and what may have caused it? Open
View article: Trust‐aware task load balancing in multi‐access edge computing based on blockchain and a zero trust security capability framework
Trust‐aware task load balancing in multi‐access edge computing based on blockchain and a zero trust security capability framework Open
The need for low‐latency service support at the network edge has increased due to new applications such as autonomous vehicles, facial recognition, and augmented reality. Multi‐access edge computing (MEC) has emerged as a promising compone…
View article: Toward Network Slicing Enabled Edge Computing: A Cloud-Native Approach for Slice Mobility
Toward Network Slicing Enabled Edge Computing: A Cloud-Native Approach for Slice Mobility Open
Network slicing is a key enabler for 5G and beyond networks that permits operators to provide scalable, flexible, and dedicated networks over a common physical infrastructure. To cope with the rising demand for Ultra-Reliable and Low-Laten…
View article: Toward Network Slicing Enabled Edge Computing: A Cloud-Native Approach for Slice Mobility
Toward Network Slicing Enabled Edge Computing: A Cloud-Native Approach for Slice Mobility Open
Network slicing is a key enabler for 5G and beyond networks that permits operators to provide scalable, flexible, and dedicated networks over a common physical infrastructure. To cope with the rising demand for Ultra-Reliable and Low-Laten…
View article: Supplemental Methods from Tyrosine Kinase Inhibition in Leukemia Induces an Altered Metabolic State Sensitive to Mitochondrial Perturbations
Supplemental Methods from Tyrosine Kinase Inhibition in Leukemia Induces an Altered Metabolic State Sensitive to Mitochondrial Perturbations Open
Supplemental Methods. This supplementary file includes additional methods for sample preparation, Seahorse analysis of oxygen consumption rates, reactive oxygen species measurements, flow cytometry analysis, NMR analysis, RT-PCR conditions…
View article: Data from Targeting Glutamine Metabolism and Redox State for Leukemia Therapy
Data from Targeting Glutamine Metabolism and Redox State for Leukemia Therapy Open
Purpose:Acute myeloid leukemia (AML) is a hematologic malignancy characterized by the accumulation of immature myeloid precursor cells. AML is poorly responsive to conventional chemotherapy and a diagnosis of AML is usually fatal. More eff…
View article: Supplementary Data from Targeting Glutamine Metabolism and Redox State for Leukemia Therapy
Supplementary Data from Targeting Glutamine Metabolism and Redox State for Leukemia Therapy Open
Supplemental Materials and Methods
View article: Supplemental Tables 1-4 from Tyrosine Kinase Inhibition in Leukemia Induces an Altered Metabolic State Sensitive to Mitochondrial Perturbations
Supplemental Tables 1-4 from Tyrosine Kinase Inhibition in Leukemia Induces an Altered Metabolic State Sensitive to Mitochondrial Perturbations Open
Supplemental Tables 1-4. Table 1: pLKO shRNA clone information and antibody information. Table 2: Combination Indices to assess for synergism. Table 3: Quantitative 1H-, 31P- and 13C-NMR analysis of K562 CML cells treated with vehicle imat…
View article: Supplementary Data from Targeting Glutamine Metabolism and Redox State for Leukemia Therapy
Supplementary Data from Targeting Glutamine Metabolism and Redox State for Leukemia Therapy Open
Figure S1. The glutaminase inhibitor CB-839 impairs glutathione metabolism in FLT3WT AML cells. Figure S2. The glutaminase inhibitor CB-839 decreases glutathione levels, but does not increase total cellular ROS levels in AML cells. Figure …
View article: Supplementary Table 2 from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer
Supplementary Table 2 from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer Open
Supplementary Table 2 - PDF file 62K, Suppl Table 2 IC50s for single agents and combination
View article: Supplemental Methods from Tyrosine Kinase Inhibition in Leukemia Induces an Altered Metabolic State Sensitive to Mitochondrial Perturbations
Supplemental Methods from Tyrosine Kinase Inhibition in Leukemia Induces an Altered Metabolic State Sensitive to Mitochondrial Perturbations Open
Supplemental Methods. This supplementary file includes additional methods for sample preparation, Seahorse analysis of oxygen consumption rates, reactive oxygen species measurements, flow cytometry analysis, NMR analysis, RT-PCR conditions…
View article: Data from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer
Data from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer Open
Purpose: The mitogen-activated protein kinase (MAPK) pathway is a crucial regulator of cell proliferation, survival, and resistance to apoptosis. MEK inhibitors are being explored as a treatment option for patients with KRAS-mutant …
View article: Data from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer
Data from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer Open
Purpose: The mitogen-activated protein kinase (MAPK) pathway is a crucial regulator of cell proliferation, survival, and resistance to apoptosis. MEK inhibitors are being explored as a treatment option for patients with KRAS-mutant …
View article: Supplementary Methods from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer
Supplementary Methods from Rational Combination of a MEK Inhibitor, Selumetinib, and the Wnt/Calcium Pathway Modulator, Cyclosporin A, in Preclinical Models of Colorectal Cancer Open
Supplementary Methods - PDF file 124K, Supplementary Methods
View article: Multi-Domain Federation Utilizing Software Defined Networking—A Review
Multi-Domain Federation Utilizing Software Defined Networking—A Review Open
The global growth of the Internet continues with an increase in accessibility, connected users and new applications in emerging fields like eGames, augmented and virtual reality. Technologies that improve reliability whilst reducing cost a…
View article: 923 Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues
923 Deep single-cell, proteogenomic insights from SARS-CoV-2 infected lung tissues Open
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged in late 2019 has spread globally, causing a pandemic of respiratory illness designated coronavirus disease 2019 (COVID-19) and is likely to lead to co…
View article: Latency Analysis for Mobile Cellular Network uRLLC Services
Latency Analysis for Mobile Cellular Network uRLLC Services Open
The fifth generation (5G) mobile network technologies include ultra-Reliable Low Latency Communications (uRLLC) capability. To fully exploit uRLLC, distributed Multi- access Edge Computing (MEC) is being developed and introduced at the net…