Mark H. Yazer
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View article: <scp>RhD</scp> ‐negative red blood cell use and conservation strategies in the Region of Southern Denmark
<span>RhD</span> ‐negative red blood cell use and conservation strategies in the Region of Southern Denmark Open
Background and Objectives Suboptimal use of RhD‐negative red blood cells (RBCs) can lead to reduced inventories of this scarce resource. Prevention of D‐alloimmunization is particularly important for RhD‐negative females of childbearing po…
View article: Simulating the blood transfusion system in Kenya: Modelling methods and exploratory analyses
Simulating the blood transfusion system in Kenya: Modelling methods and exploratory analyses Open
The process of collecting blood from donors and making it available for transfusion requires a complex series of operations involving multiple actors and different resources at each step. Ensuring hospitals receive adequate and safe blood …
View article: Early achievement of hemostasis defined by transfusion velocity: A possible mechanism for whole blood survival benefit
Early achievement of hemostasis defined by transfusion velocity: A possible mechanism for whole blood survival benefit Open
INTRODUCTION Whole blood resuscitation is associated with survival benefits in observational cohort studies. The mechanisms responsible for outcome benefits have not been adequately determined. We sought to characterize the achievement of …
View article: An unusual case of reagent interference in transfusion medicine workup: Pan reactive indirect antiglobulin test caused by commercial saline solution
An unusual case of reagent interference in transfusion medicine workup: Pan reactive indirect antiglobulin test caused by commercial saline solution Open
Background At the regional transfusion service in the Region of Southern Denmark, serological investigations are primarily carried out using column agglutination techniques. This case study examines an unusual instance of reagent interfere…
View article: Impact of variable titer COVID-19 convalescent plasma and recipient SARS-CoV2-specific humoral immunity on survival in hospitalized patients
Impact of variable titer COVID-19 convalescent plasma and recipient SARS-CoV2-specific humoral immunity on survival in hospitalized patients Open
COVID-19 convalescent plasma (CCP) was one of the first therapies to receive emergency use authorization for management of COVID-19. We assessed the effectiveness of CCP in a propensity-matched analysis, and whether the presence of antibod…
View article: A review of attitudes to urgent <scp>RhD</scp>‐positive transfusions in female patients and the risk for hemolytic disease of the fetus and newborn
A review of attitudes to urgent <span>RhD</span>‐positive transfusions in female patients and the risk for hemolytic disease of the fetus and newborn Open
At the onset of the resuscitation of a patient with life-threatening bleeding, when their ABO and RhD blood groups are not likely to be known, group O red blood cells (RBCs) or low titer group O whole blood (LTOWB) must be transfused to en…
View article: Early GFAP and UCH-L1 point-of-care biomarker measurements for the prediction of traumatic brain injury and progression in patients with polytrauma and hemorrhagic shock
Early GFAP and UCH-L1 point-of-care biomarker measurements for the prediction of traumatic brain injury and progression in patients with polytrauma and hemorrhagic shock Open
OBJECTIVE Traumatic brain injury (TBI) and hemorrhage are responsible for the largest proportion of all trauma-related deaths. In polytrauma patients at risk of hemorrhage and TBI, the diagnosis, prognosis, and management of TBI remain poo…
View article: Early Cold Stored Platelet Transfusion Following Severe Injury
Early Cold Stored Platelet Transfusion Following Severe Injury Open
Objective: To determine the feasibility, efficacy, and safety of early cold stored platelet transfusion compared with standard care resuscitation in patients with hemorrhagic shock. Background: Data demonstrating the safety and efficacy of…
View article: Impact of systematic variations in hematocrit and platelet count on thrombelastometry tissue factor activated assay parameters
Impact of systematic variations in hematocrit and platelet count on thrombelastometry tissue factor activated assay parameters Open
Background Thromboelastogram testing is increasingly being used to manage patients with massive bleeding. An earlier study found that the test results were influenced by the hematocrit (Hct) and platelet (PLT) concentrations. This study so…
View article: Protocol: identifying policy, system, and environment change interventions to enhance availability of blood for transfusion in Kenya, a mixed-methods study
Protocol: identifying policy, system, and environment change interventions to enhance availability of blood for transfusion in Kenya, a mixed-methods study Open
View article: Incompatible plasma transfusion is not associated with increased mortality in civilian trauma patients
Incompatible plasma transfusion is not associated with increased mortality in civilian trauma patients Open
Receipt of incompatible plasma was not independently associated with increased mortality in trauma patients. Prospective studies are needed to confirm these findings.
View article: Hemostatic In Vitro Properties of Novel Plasma Supernatants Produced from Late-storage Low-titer Type O Whole Blood
Hemostatic In Vitro Properties of Novel Plasma Supernatants Produced from Late-storage Low-titer Type O Whole Blood Open
Background The use of low-titer group O whole blood is increasing. To reduce wastage, unused units can be converted to packed red blood cells. Supernatant is currently discarded post-conversion; however, it could be a valuable transfusable…
View article: Evaluation of critical care burden following traumatic injury from two randomized controlled trials
Evaluation of critical care burden following traumatic injury from two randomized controlled trials Open
Trauma resuscitation practices have continued to improve with new advances targeting prehospital interventions. The critical care burden associated with severely injured patients at risk of hemorrhage has been poorly characterized. We aim …
View article: Not as “D”eadly as once thought – the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma
Not as “D”eadly as once thought – the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma Open
The use of blood products to resuscitate injured and massively bleeding patients in the prehospital and early in-hospital phase of the resuscitation is increasing. Using group O red blood cells (RBC) and low titer group O whole blood (LTOW…
View article: Lipidomic signatures align with inflammatory patterns and outcomes in critical illness
Lipidomic signatures align with inflammatory patterns and outcomes in critical illness Open
View article: Modelling the outcomes of different red blood cell transfusion strategies for the treatment of traumatic haemorrhage in the prehospital setting in the <scp>United Kingdom</scp>
Modelling the outcomes of different red blood cell transfusion strategies for the treatment of traumatic haemorrhage in the prehospital setting in the <span>United Kingdom</span> Open
Background and Objectives The limited supply and increasing demand of group O RhD‐negative red blood cells (RBCs) have resulted in other transfusion strategies being explored by blood services that carry potential risks but may still provi…
View article: How do we forecast tomorrow’s transfusion? Prehospital transfusion
How do we forecast tomorrow’s transfusion? Prehospital transfusion Open
View article: Prehospital plasma is associated with survival principally in patients transferred from the scene of injury: A secondary analysis of the PAMPer trial
Prehospital plasma is associated with survival principally in patients transferred from the scene of injury: A secondary analysis of the PAMPer trial Open
View article: Index
Index Open
AABB (Association for the Advancement of Blood and Biotherapies) accreditation 499 ABCDE approach 121 ABLE trial 150 ABO blood groups 1, 269, 270-271, 294 antibody detection methods 67-68 antibody screening test 67 autoantibodies 69 centra…
View article: Potential of cell tracking velocimetry as an economical and portable hematology analyzer
Potential of cell tracking velocimetry as an economical and portable hematology analyzer Open
Anemia and iron deficiency continue to be the most prevalent nutritional disorders in the world, affecting billions of people in both developed and developing countries. The initial diagnosis of anemia is typically based on several markers…
View article: Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses
Multi-omic analysis in injured humans: Patterns align with outcomes and treatment responses Open
View article: Perception of risk in massive transfusion as it relates to fetal outcomes: A survey of surgeons and nurses at one American trauma center
Perception of risk in massive transfusion as it relates to fetal outcomes: A survey of surgeons and nurses at one American trauma center Open
Background The use of blood products early in the resuscitation of bleeding trauma patients is widely accepted, but made difficult by limited supplies of D− red blood cell (RBC)‐containing products. Use of D+ RBC‐containing products would …
View article: Civilian walking blood bank emergency preparedness plan
Civilian walking blood bank emergency preparedness plan Open
Background The current global pandemic has created unprecedented challenges in the blood supply network. Given the recent shortages, there must be a civilian plan for massively bleeding patients when there are no blood products on the shel…
View article: Quantification of <scp>anti‐A</scp> of <scp>IgM</scp> or <scp>IgG</scp> isotype using three different methodologies
Quantification of <span>anti‐A</span> of <span>IgM</span> or <span>IgG</span> isotype using three different methodologies Open
Background Reliability of ABO‐antibody measurement is important in the context of supplying low‐titer ABO incompatible plasma‐containing blood products. This study investigated the correlation of anti‐A measurements between three different…
View article: Introduction to <scp>THOR</scp> supplement
Introduction to <span>THOR</span> supplement Open
Welcome to the Trauma, Hemostasis, Oxygenation, and Research (THOR) Network's fifth supplement in TRANSFUSION. The THOR network aims to bring together prehospital providers, clinicians, blood bankers, and scientists from civilian and milit…
View article: Potential of Cell Tracking Velocimetry as an Economical and Portable Hematology Analyzer
Potential of Cell Tracking Velocimetry as an Economical and Portable Hematology Analyzer Open
Anemia and iron deficiency continue to be the most prevalent nutritional disorders in the world, affecting billions of people in both developed and developing countries. The initial diagnosis of anemia is typically based on several markers…
View article: International Forum on the Collection and Use of COVID‐19 Convalescent Plasma: Responses
International Forum on the Collection and Use of COVID‐19 Convalescent Plasma: Responses Open
Vox SanguinisVolume 116, Issue 10 p. e71-e120 International Forum International Forum on the Collection and Use of COVID-19 Convalescent Plasma: Responses Arwa Z. Al-Riyami, Arwa Z. Al-Riyami [email protected] orcid.org/0000-0001-8649-0650…
View article: International Forum on the Collection and Use of COVID‐19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary
International Forum on the Collection and Use of COVID‐19 Convalescent Plasma: Protocols, Challenges and Lessons Learned: Summary Open
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory coronavirus 2(SARS-CoV-2), has rapidly spread since its first declaration by the World Health Organization (WHO) as a global pandemic in March 2020 [1]. Until vaccinat…
View article: Intrinsically magnetic susceptibility in human blood and its potential impact on cell separation: Non-classical and intermediate monocytes have the strongest magnetic behavior in fresh human blood
Intrinsically magnetic susceptibility in human blood and its potential impact on cell separation: Non-classical and intermediate monocytes have the strongest magnetic behavior in fresh human blood Open
View article: Age of thawed plasma does not affect clinical outcomes or biomarker expression in patients receiving prehospital thawed plasma: a PAMPer secondary analysis
Age of thawed plasma does not affect clinical outcomes or biomarker expression in patients receiving prehospital thawed plasma: a PAMPer secondary analysis Open
Background Prehospital plasma administration during air medical transport reduces the endotheliopathy of trauma, circulating pro-inflammatory cytokines, and 30-day mortality among traumatically injured patients at risk of hemorrhagic shock…