Mark Handley
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View article: 20 Years in Life of a Smart Building: A retrospective
20 Years in Life of a Smart Building: A retrospective Open
Operating an intelligent smart building automation system in 2025 is met with many challenges: hardware failures, vendor obsolescence, evolving security threats and more. None of these have been comprehensibly addressed by the industrial b…
View article: Designing a Platform for Flexible and Performant Virtual Routers on Commodity Hardware.
Designing a Platform for Flexible and Performant Virtual Routers on Commodity Hardware. Open
Multi-core CPUs, along with recent advances in memory and buses, render commodity hardware a strong candidate for software router virtualization. In this context, we present the design of a new platform for virtual routers on x86 hardware.…
View article: FASTFLOW: Flexible Adaptive Congestion Control for High-Performance Datacenters
FASTFLOW: Flexible Adaptive Congestion Control for High-Performance Datacenters Open
The increasing demand of machine learning (ML) workloads in datacenters places significant stress on current congestion control (CC) algorithms, many of which struggle to maintain performance at scale. These workloads generate bursty, sync…
View article: Reliable Low-Delay Routing In Space with Routing-Oblivious LEO Satellites
Reliable Low-Delay Routing In Space with Routing-Oblivious LEO Satellites Open
Large networks of Low Earth Orbit (LEO) satellites are being built using inter-satellite lasers. These networks promise to offer low-latency wide-area connectivity, but reliably routing such traffic is difficult, as satellites are very res…
View article: Supplementary Figures 1-4 and Legends from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Supplementary Figures 1-4 and Legends from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling Open
Supplementary Figures 1-4 and Legends from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
View article: Data from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Data from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling Open
Matrix metalloproteinase-7 (MMP-7) is localized to epithelial cells and is up-regulated in many cancers and in inflammation. We now report that MMP-7 targets a key mesenchymal cell type, the myofibroblast. Recombinant MMP-7 stimulated the …
View article: Supplementary Figures 1-4 and Legends from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Supplementary Figures 1-4 and Legends from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling Open
Supplementary Figures 1-4 and Legends from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
View article: Adobe PDF - CAN_8-15-05_Hemers.pdf from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Adobe PDF - CAN_8-15-05_Hemers.pdf from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling Open
Adobe PDF - CAN_8-15-05_Hemers.pdf from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
View article: Adobe PDF - CAN_8-15-05_Hemers.pdf from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Adobe PDF - CAN_8-15-05_Hemers.pdf from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling Open
Adobe PDF - CAN_8-15-05_Hemers.pdf from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
View article: Data from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling
Data from Insulin-Like Growth Factor Binding Protein-5 Is a Target of Matrix Metalloproteinase-7: Implications for Epithelial-Mesenchymal Signaling Open
Matrix metalloproteinase-7 (MMP-7) is localized to epithelial cells and is up-regulated in many cancers and in inflammation. We now report that MMP-7 targets a key mesenchymal cell type, the myofibroblast. Recombinant MMP-7 stimulated the …
View article: SDP: Session Description Protocol
SDP: Session Description Protocol Open
This memo defines the Session Description Protocol (SDP). SDP is intended for describing multimedia sessions for the purposes of session announcement, session invitation, and other forms of multimedia session initiation. This document obso…
View article: TCP Extensions for Multipath Operation with Multiple Addresses
TCP Extensions for Multipath Operation with Multiple Addresses Open
TCP/IP communication is currently restricted to a single path per connection, yet multiple paths often exist between peers. The simultaneous use of these multiple paths for a TCP/IP session would improve resource usage within the network a…
View article: On low-latency-capable topologies, and their impact on the design of intra-domain routing
On low-latency-capable topologies, and their impact on the design of intra-domain routing Open
An ISP's customers increasingly demand delivery of their traffic without congestion and with low latency. The ISP's topology, routing, and traffic engineering, often over multiple paths, together determine congestion and latency within its…
View article: Re-architecting datacenter networks and stacks for low latency and high performance
Re-architecting datacenter networks and stacks for low latency and high performance Open
Modern datacenter networks provide very high capacity via redundant Clos topologies and low switch latency, but transport protocols rarely deliver matching performance. We present NDP, a novel data-center transport architecture that achiev…
View article: TOO TIRED TO CARE: RELIGIOUS ORIENTATIONS’ RELATIONSHIP WITH EGO-DEPLETED EMPATHY
TOO TIRED TO CARE: RELIGIOUS ORIENTATIONS’ RELATIONSHIP WITH EGO-DEPLETED EMPATHY Open
Psychological research into various aspects of religiosity, empathy, and self-regulation has grown throughout the years. Using Wulff’s (1997) literal verses symbolic bipolar dimension of religiosity, Duriez (2004) found that participants w…