Mark Hesketh
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Altered macrophage phenotypes impair wound healing Open
One of the defining features of chronic wounds is their high levels of inflammation. Patients present with high levels of inflammation, around 80%, of cells at the wound margin being macrophages and with wound fluid laden with pro- inflamm…
Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing Open
Macrophages and inflammation play a beneficial role during wound repair with macrophages regulating a wide range of processes, such as removal of dead cells, debris and pathogens, through to extracellular matrix deposition re-vascularisati…