Mark Khemmani
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View article: Characterizing the urobiome in geriatric males with chronic indwelling urinary catheters: an exploratory longitudinal study
Characterizing the urobiome in geriatric males with chronic indwelling urinary catheters: an exploratory longitudinal study Open
The impact of chronic indwelling urinary catheters (IUCs) on the composition and stability of the urinary microbiota remains unknown. The primary aim of this study was to describe the urinary microbiomes of geriatric males with chronic IUC…
View article: Role of novel polysaccharide layers in assembly of the exosporium, the outermost protein layer of the <i>Bacillus anthracis</i> spore
Role of novel polysaccharide layers in assembly of the exosporium, the outermost protein layer of the <i>Bacillus anthracis</i> spore Open
A fundamental question in cell biology is how cells assemble their outer layers. The bacterial endospore is a well‐established model for cell layer assembly. However, the assembly of the exosporium, a complex protein shell comprising the o…
View article: Characterization of Bacillus anthracis Spore Proteins Using a Nanoscaffold Vaccine Platform
Characterization of Bacillus anthracis Spore Proteins Using a Nanoscaffold Vaccine Platform Open
Subunit vaccines are theoretically safe and easy to manufacture but require effective adjuvants and delivery systems to yield protective immunity, particularly at critical mucosal sites such as the lung. We investigated nanolipoprotein par…
View article: Contributions of crust proteins to spore surface properties in <i>Bacillus subtilis</i>
Contributions of crust proteins to spore surface properties in <i>Bacillus subtilis</i> Open
Summary Surface properties, such as adhesion and hydrophobicity, constrain dispersal of bacterial spores in the environment. In Bacillus subtilis , these properties are influenced by the outermost layer of the spore, the crust . Previous w…
View article: Coordinated Assembly of the Bacillus anthracis Coat and Exosporium during Bacterial Spore Outer Layer Formation
Coordinated Assembly of the Bacillus anthracis Coat and Exosporium during Bacterial Spore Outer Layer Formation Open
This work dramatically improves our understanding of the assembly of the outermost layer of the B. anthracis spore, the exosporium, a layer that encases spores from many bacterial species and likely plays important roles in the spore’s int…