Mark Korpics
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View article: A Preliminary Study on Deep Learning-Based Plan Quality Prediction in Gamma Knife Radiosurgery for Brain Metastases
A Preliminary Study on Deep Learning-Based Plan Quality Prediction in Gamma Knife Radiosurgery for Brain Metastases Open
Background/Objectives: GK plan quality is strongly affected by lesion size and shape, and the same evaluation metrics may not be directly comparable across patients with different anatomies. This study proposes a deep learning-based method…
View article: Limited survival benefit in patients diagnosed with glioblastoma post-2016: a SEER population based registry analysis
Limited survival benefit in patients diagnosed with glioblastoma post-2016: a SEER population based registry analysis Open
This population-based cohort demonstrated minimal change in survival for patients diagnosed with GBM before and after FDA approval of TTFs in 2015.
View article: Online correction of intrafraction motion during volumetric modulated arc therapy for prostate radiotherapy using fiducial‐based kV imaging: A cohort study quantifying the frequency of shifts and analysis of men at highest risk
Online correction of intrafraction motion during volumetric modulated arc therapy for prostate radiotherapy using fiducial‐based kV imaging: A cohort study quantifying the frequency of shifts and analysis of men at highest risk Open
Background Various methods exist to correct for intrafraction motion (IFM) of the prostate during radiotherapy. We sought to characterize setup corrections in our practice informed by the TrueBeam Advanced imaging package, and analyze fact…
View article: A hybrid computer vision model to predict lung cancer in diverse populations
A hybrid computer vision model to predict lung cancer in diverse populations Open
PURPOSE Disparities of lung cancer incidence exist in Black populations and screening criteria underserve Black populations due to disparately elevated risk in the screening eligible population. Prediction models that integrate clinical an…
View article: The Patterns of Failure and Prognostic Impact of Tumor Location in Patients Undergoing Reirradiation for Glioblastoma
The Patterns of Failure and Prognostic Impact of Tumor Location in Patients Undergoing Reirradiation for Glioblastoma Open
Introduction RTOG 1205 is the only randomized study to evaluate the safety and efficacy of reirradiation (reRT) in recurrent glioblastoma (GBM). While this study showed that reRT was safe and improves progression-free survival (PFS), an im…
View article: Radiation therapy takes advantage of cancer’s poor DNA repair abilities – an oncologist and physicist explain how
Radiation therapy takes advantage of cancer’s poor DNA repair abilities – an oncologist and physicist explain how Open
View article: Radiomics Based Assessment of Tumor Infiltrating CD8 T-Cells Predicts Induction Systemic Therapy Response in HPV+ Oropharyngeal Cancer: Exploratory Analysis of Prospective Trials
Radiomics Based Assessment of Tumor Infiltrating CD8 T-Cells Predicts Induction Systemic Therapy Response in HPV+ Oropharyngeal Cancer: Exploratory Analysis of Prospective Trials Open
View article: Partial tumor irradiation plus pembrolizumab in treating large advanced solid tumor metastases
Partial tumor irradiation plus pembrolizumab in treating large advanced solid tumor metastases Open
BACKGROUNDWe previously demonstrated the safety of stereotactic body radiotherapy followed by pembrolizumab (SBRT+P) in patients with advanced solid tumors. This phase I clinical trial was expanded to study the safety of partial tumor irra…
View article: Decreased overall survival in patients with locally advanced head and neck cancer receiving definitive radiotherapy and concurrent cetuximab: National Cancer Database analysis
Decreased overall survival in patients with locally advanced head and neck cancer receiving definitive radiotherapy and concurrent cetuximab: National Cancer Database analysis Open
Background Recently, randomized trials have questioned the efficacy of cetuximab‐based bioradiotherapy compared to chemoradiation for patients with squamous cell carcinoma of the oropharynx, larynx, and hypopharynx (HNSCC). We compared the…
View article: Linear accelerator-based stereotactic radiosurgery for glossopharyngeal neuralgia is safe and effective - Report of two cases.
Linear accelerator-based stereotactic radiosurgery for glossopharyngeal neuralgia is safe and effective - Report of two cases. Open
View article: Prospective Evaluation of Stereotactic Body Radiotherapy and Immunotherapy for Mediastinal and Hilar Lymph Node Metastases
Prospective Evaluation of Stereotactic Body Radiotherapy and Immunotherapy for Mediastinal and Hilar Lymph Node Metastases Open
View article: Stereotactic Body Radiation Therapy and Immunotherapy in Abdominal and Pelvic Lymph Node Metastases
Stereotactic Body Radiation Therapy and Immunotherapy in Abdominal and Pelvic Lymph Node Metastases Open
View article: Impact of anatomic site of distant metastasis on survival in salivary gland cancers
Impact of anatomic site of distant metastasis on survival in salivary gland cancers Open
Background As exemplified in patients with adenoid cystic carcinoma (ACC), metastatic salivary gland cancers display heterogenous behavior. Although anatomic site of metastasis has been suggested to be prognostic for survival in this popul…
View article: Patterns of Care and Survival Outcomes for Odontogenic Cancers
Patterns of Care and Survival Outcomes for Odontogenic Cancers Open
Objectives Our understanding of odontogenic cancers is limited primarily to case studies given the rarity of these head and neck neoplasms. Using the National Cancer Database, we report the treatment patterns and survival outcomes for one …
View article: Patterns Of Care And Survival Outcomes Of Squamous Cell Carcinoma Of The Orbit: A National Cancer Database Analysis
Patterns Of Care And Survival Outcomes Of Squamous Cell Carcinoma Of The Orbit: A National Cancer Database Analysis Open
View article: Utilizing the TrueBeam Advanced Imaging Package to monitor intrafraction motion with periodic kV imaging and automatic marker detection during VMAT prostate treatments
Utilizing the TrueBeam Advanced Imaging Package to monitor intrafraction motion with periodic kV imaging and automatic marker detection during VMAT prostate treatments Open
Background Fiducial markers are frequently used before treatment for image‐guided patient setup in radiation therapy (RT), but can also be used during treatment for image‐guided intrafraction motion detection. This report describes our imp…
View article: Patient and physician reported toxicity with two-fraction definitive high-dose-rate prostate brachytherapy: the impact of implant interval
Patient and physician reported toxicity with two-fraction definitive high-dose-rate prostate brachytherapy: the impact of implant interval Open
HDR brachytherapy for prostate cancer is a well-tolerated treatment. The interval between treatments is not associated with differences in patient-reported QOL or physician-graded toxicities.
View article: Patterns of Care and Outcomes of Intensity-Modulated Radiotherapy and 3D Conformal Radiotherapy for Early Stage Glottic Cancer: A National Cancer Database Analysis
Patterns of Care and Outcomes of Intensity-Modulated Radiotherapy and 3D Conformal Radiotherapy for Early Stage Glottic Cancer: A National Cancer Database Analysis Open
Early stage glottic cancer has traditionally been treated with 3D conformal radiotherapy (3DCRT). However, intensity-modulated radiotherapy (IMRT) has been recently adopted as an alternative to decrease toxicity. Here, we compared the usag…
View article: A Validated Radiomics T-cell Score Predicts Response to Multi-site SBRT Combined with Pembrolizumab
A Validated Radiomics T-cell Score Predicts Response to Multi-site SBRT Combined with Pembrolizumab Open
View article: Transitioning From a Low-Dose-Rate to a High-Dose-Rate Prostate Brachytherapy Program: Comparing Initial Dosimetry and Improving Workflow Efficiency Through Targeted Interventions
Transitioning From a Low-Dose-Rate to a High-Dose-Rate Prostate Brachytherapy Program: Comparing Initial Dosimetry and Improving Workflow Efficiency Through Targeted Interventions Open
View article: Comparing Acute Toxicity Profiles for High Dose Rate Prostate Brachytherapy Patients Receiving Two Implants Separated by a One-Week Versus Two-Week Interval
Comparing Acute Toxicity Profiles for High Dose Rate Prostate Brachytherapy Patients Receiving Two Implants Separated by a One-Week Versus Two-Week Interval Open
View article: Patients With Muscle-invasive Squamous Cell Carcinoma of the Bladder Have Worse Survival Compared to Other Histologies When Undergoing Definitive Radiation Therapy
Patients With Muscle-invasive Squamous Cell Carcinoma of the Bladder Have Worse Survival Compared to Other Histologies When Undergoing Definitive Radiation Therapy Open
View article: Intensity Modulated Radiation Therapy in Muscle-Invasive Bladder Cancer: Predictors of Utilization and Survival Outcomes
Intensity Modulated Radiation Therapy in Muscle-Invasive Bladder Cancer: Predictors of Utilization and Survival Outcomes Open
View article: Concurrent chemotherapy is associated with improved survival in elderly patients with bladder cancer undergoing radiotherapy
Concurrent chemotherapy is associated with improved survival in elderly patients with bladder cancer undergoing radiotherapy Open
BACKGROUND The current study was conducted to compare the overall survival (OS) of concurrent chemoradiotherapy (CCRT) versus radiotherapy (RT) alone in elderly patients (those aged ≥80 years) with muscle‐invasive bladder cancer (MIBC). ME…
View article: Variability of Radiation Oncologists’ Chemoradiation Therapy Patterns of Care and the Impact of Multidisciplinary Clinics in Muscle-Invasive Bladder Cancer
Variability of Radiation Oncologists’ Chemoradiation Therapy Patterns of Care and the Impact of Multidisciplinary Clinics in Muscle-Invasive Bladder Cancer Open
View article: Observer Evaluation of a Metal Artifact Reduction Algorithm Applied to Head and Neck Cone Beam Computed Tomography Images
Observer Evaluation of a Metal Artifact Reduction Algorithm Applied to Head and Neck Cone Beam Computed Tomography Images Open
View article: Metal Artifact Reduction in Cone-Beam Computed Tomography for Head and Neck Radiotherapy
Metal Artifact Reduction in Cone-Beam Computed Tomography for Head and Neck Radiotherapy Open
Purpose: To evaluate a method for reducing metal artifacts, arising from dental fillings, on cone-beam computed tomography images. Materials and Methods: A projection interpolation algorithm is applied to cone-beam computed tomography imag…