Andrew M. Jones
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View article: <sup>13</sup> C-labelled glucose-fructose show greater exogenous and whole-body CHO oxidation and lower O <sub>2</sub> cost of running at 120 versus 60 and 90 g·h <sup>−1</sup> in elite male marathoners
<sup>13</sup> C-labelled glucose-fructose show greater exogenous and whole-body CHO oxidation and lower O <sub>2</sub> cost of running at 120 versus 60 and 90 g·h <sup>−1</sup> in elite male marathoners Open
We used stable isotope methodology to evaluate exogenous rates of CHO oxidation in elite male marathoners. We report that 120 (maltodextrin:fructose ratio 1:1) g·h −1 CHO induces greater whole body and exogenous CHO oxidation compared with…
View article: Consensus Statements—Optimizing Performance of the Elite Athlete
Consensus Statements—Optimizing Performance of the Elite Athlete Open
The International Consensus Conference “Optimising Performance of the Elite Athlete,” held in November 2024, brought together 29 scientists, some coaches, and athletes to establish evidence‐based consensus statements aimed at enhancing eli…
View article: The association of weight status with glycemic control, diabetes related complications and anti-hyperglycemic medication use in patients with type 2 diabetes mellitus: The results of the Australian National Diabetes Audit (ANDA) 2015–2022
The association of weight status with glycemic control, diabetes related complications and anti-hyperglycemic medication use in patients with type 2 diabetes mellitus: The results of the Australian National Diabetes Audit (ANDA) 2015–2022 Open
Patients with T2DM and obesity have poorer glycemic control, higher utilisation of anti-glycemic medications and greater odds of diabetes related complications. Approaches to optimise glycemic control that also deliver weight reduction sho…
View article: Durability as an index of endurance exercise performance: Methodological considerations
Durability as an index of endurance exercise performance: Methodological considerations Open
Endurance athletes routinely complete physiological assessments to predict performance, inform training programmes and monitor subsequent training adaptations. This profiling is typically performed with the athlete in a ‘fresh’ (i.e., rest…
View article: Physiological Resilience: What Is It and How Might It Be Trained?
Physiological Resilience: What Is It and How Might It Be Trained? Open
Physiological resilience has recently been recognized as an additional factor that influences endurance exercise performance. It has thus been incorporated into a modified, contemporary version of “the Joyner model” which acknowledges that…
View article: Blue plaque review series: A.V. Hill, athletic records and the birth of exercise physiology
Blue plaque review series: A.V. Hill, athletic records and the birth of exercise physiology Open
One hundred years ago, A.V. Hill authored three manuscripts analysing athletic world records from a physiological perspective. That analysis, grounded in Hill's understanding of contemporary muscle bioenergetics, provides a fascinating ske…
View article: Dose-response relationship between dietary nitrate intake and nitric oxide congeners in various blood compartments and skeletal muscle: Differential effects on skeletal muscle torque and velocity
Dose-response relationship between dietary nitrate intake and nitric oxide congeners in various blood compartments and skeletal muscle: Differential effects on skeletal muscle torque and velocity Open
Plasma nitrate (NO3-) and nitrite (NO2-) increase in a dose-dependent manner following NO3- ingestion. To explore if the same dose-response relationship applies to other nitric oxide (NO) congeners in different blood compartments and skele…
View article: Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and <i>APOE4</i> genotype
Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and <i>APOE4</i> genotype Open
Apolipoprotein E4 (APOE4) genotype and nitric oxide (NO) deficiency are risk factors for age-associated cognitive decline. The oral microbiome plays a critical role in maintaining NO bioavailability during aging. The aim of this study was …
View article: Effects of low and high dietary nitrate intake on human saliva, plasma and skeletal muscle nitrate and nitrite concentrations and their functional consequences
Effects of low and high dietary nitrate intake on human saliva, plasma and skeletal muscle nitrate and nitrite concentrations and their functional consequences Open
Dietary nitrate (NO3-) supplementation has been shown to reduce blood pressure (BP), improve exercise performance, and alter the oral microbiome. Following a "control" diet (CON), we manipulated dietary NO3- intake to examine the effect of…
View article: Localisation of nitrate-reducing and highly abundant microbial communities in the oral cavity
Localisation of nitrate-reducing and highly abundant microbial communities in the oral cavity Open
The nitrate (NO 3 - ) reducing bacteria resident in the oral cavity have been implicated as key mediators of nitric oxide (NO) homeostasis and human health. NO 3 - -reducing oral bacteria reduce inorganic dietary NO 3 - to nitrite (NO 2 - …
View article: Low Carbohydrate, High Fat Diet Alters the Oral Microbiome without Negating the Nitrite Response to Beetroot Juice Supplementation
Low Carbohydrate, High Fat Diet Alters the Oral Microbiome without Negating the Nitrite Response to Beetroot Juice Supplementation Open
A low carbohydrate, high fat (LCHF) diet in athletes increases fat oxidation but impairs sports performance, potentially due to impaired exercise economy. Dietary nitrate supplementation can improve exercise economy via an increase in nitr…
View article: Evolution of 1500-m Olympic Running Performance
Evolution of 1500-m Olympic Running Performance Open
Purpose : This study determined the evolution of performance and pacing for each winner of the men’s Olympic 1500-m running track final from 1924 to 2020. Methods : Data were obtained from publicly available sources. When official splits w…
View article: A Perspective on High-Intensity Interval Training for Performance and Health
A Perspective on High-Intensity Interval Training for Performance and Health Open
Interval training is a simple concept that refers to repeated bouts of relatively hard work interspersed with recovery periods of easier work or rest. The method has been used by high-level athletes for over a century to improve performanc…
View article: The fourth dimension: physiological resilience as an independent determinant of endurance exercise performance
The fourth dimension: physiological resilience as an independent determinant of endurance exercise performance Open
Endurance exercise performance is known to be closely associated with the three physiological pillars of maximal O 2 uptake (), economy or efficiency during submaximal exercise, and the fractional utilisation of (linked to metabolic/lactat…
View article: Multitissue responses to exercise: a MoTrPAC feasibility study
Multitissue responses to exercise: a MoTrPAC feasibility study Open
This study highlights the feasibility of key aspects of the MoTrPAC adult human clinical protocols. This initial preview of what can be expected from acute exercise trial data from MoTrPAC provides an impetus for scientists to design exerc…
View article: Competition Between Desired Competitive Result, Tolerable Homeostatic Disturbance, and Psychophysiological Interpretation Determines Pacing Strategy
Competition Between Desired Competitive Result, Tolerable Homeostatic Disturbance, and Psychophysiological Interpretation Determines Pacing Strategy Open
Scientific interest in pacing goes back >100 years. Contemporary interest, both as a feature of athletic competition and as a window into understanding fatigue, goes back >30 years. Pacing represents the pattern of energy use designed to p…
View article: Oral Temperature and pH Influence Dietary Nitrate Metabolism in Healthy Adults
Oral Temperature and pH Influence Dietary Nitrate Metabolism in Healthy Adults Open
This study tested the hypothesis that the increases in salivary and plasma [NO2−] after dietary NO3− supplementation would be greater when oral temperature and pH were independently elevated, and increased further when oral temperature and…
View article: Critical power: a paradigm‐shift for benchmarking exercise testing and prescription
Critical power: a paradigm‐shift for benchmarking exercise testing and prescription Open
Inherent in the work of Collins et al. (2022) is the notion that prescription of exercise intensity relative to CP (and also the gas exchange threshold, GET; see Lansley et al., 2011) will reduce the variability in physiological responses …
View article: <scp><sup>15</sup>N</scp>‐labeled dietary nitrate supplementation increases human skeletal muscle nitrate concentration and improves muscle torque production
<span><sup>15</sup>N</span>‐labeled dietary nitrate supplementation increases human skeletal muscle nitrate concentration and improves muscle torque production Open
Aim Dietary nitrate (NO 3 − ) supplementation increases nitric oxide bioavailability and can enhance exercise performance. We investigated the distribution and metabolic fate of ingested NO 3 − at rest and during exercise with a focus on s…
View article: Physiological and performance effects of dietary nitrate and N-acetylcysteine supplementation during prolonged heavy-intensity cycling
Physiological and performance effects of dietary nitrate and N-acetylcysteine supplementation during prolonged heavy-intensity cycling Open
The purpose of this study was to investigate effects of concurrent and independent administration of dietary nitrate (NO3-), administered as NO3--rich beetroot juice (BR; ~12.4 mmol of NO3-), and N-acetylcysteine (NAC; 70 mg·kg-1) on physi…