Mark McClendon
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View article: Craniomaxillofacial Bone Regeneration with Attenuated Early Inflammatory Response by Sustained-release of BMP-2 from a Supramolecular Polymer Slurry
Craniomaxillofacial Bone Regeneration with Attenuated Early Inflammatory Response by Sustained-release of BMP-2 from a Supramolecular Polymer Slurry Open
Purpose Bone morphogenic proteins (BMPs) are pivotal in craniomaxillofacial surgery for bone reconstruction. However, their side effects, such as severe edema and local inflammation, limit their use. Nanoscale peptide amphiphiles (PAs) sel…
View article: Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia
Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia Open
Auditory hair cells form precise and sensitive staircase-like actin protrusions known as stereocilia. These specialized microvilli detect deflections induced by sound through the activation of mechano-electrical transduction (MET) channels…
View article: Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia
Myosin XVA isoforms participate in the mechanotransduction-dependent remodeling of the actin cytoskeleton in auditory stereocilia Open
Auditory hair cells form precise and sensitive staircase-like actin protrusions known as stereocilia. These specialized microvilli detect deflections induced by sound through the activation of mechano-electrical transduction (MET) channels…
View article: A bioactive supramolecular and covalent polymer scaffold for cartilage repair in a sheep model
A bioactive supramolecular and covalent polymer scaffold for cartilage repair in a sheep model Open
Regeneration of hyaline cartilage in human-sized joints remains a clinical challenge, and it is a critical unmet need that would contribute to longer healthspans. Injectable scaffolds for cartilage repair that integrate both bioactivity an…
View article: A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor
A supramolecular polymer-collagen microparticle slurry for bone regeneration with minimal growth factor Open
View article: EXTH-48. BMP4 BINDING PEPTIDE AMPHIPHILE NANOFIBERS FOR THE TREATMENT OF PEDIATRIC HIGH-GRADE GLIOMAS
EXTH-48. BMP4 BINDING PEPTIDE AMPHIPHILE NANOFIBERS FOR THE TREATMENT OF PEDIATRIC HIGH-GRADE GLIOMAS Open
Pediatric high-grade glioma (pHGG) is among the most formidable cancers occurring in childhood. Bone morphogenetic protein 4 (BMP4) reduces the number of glioma stem-like cells and induces apoptosis. Treating tumors with exogenous BMP4 cou…
View article: Bone Morphogenetic Protein 4 Targeting Glioma Stem-Like Cells for Malignant Glioma Treatment: Latest Advances and Implications for Clinical Application
Bone Morphogenetic Protein 4 Targeting Glioma Stem-Like Cells for Malignant Glioma Treatment: Latest Advances and Implications for Clinical Application Open
Malignant gliomas are heterogeneous neoplasms. Glioma stem-like cells (GSCs) are undifferentiated and self-renewing cells that develop and maintain these tumors. These cells are the main population that resist current therapies. Genomic an…
View article: Bone Morphogenetic Protein 4 Targeting Glioma Stem-Like Cells for Malignant Glioma Treatment: Latest Advances and Implications for Clinical Application
Bone Morphogenetic Protein 4 Targeting Glioma Stem-Like Cells for Malignant Glioma Treatment: Latest Advances and Implications for Clinical Application Open
Malignant gliomas are heterogeneous neoplasms. Glioma stem-like cells (GSCs) are undifferentiated and self-renewing cells that develop and maintain these tumors. These cells are the main population that resist current therapies. Genomic an…
View article: EXTH-18. PEPTIDE NANO-STRUCTURES ENHANCE PEDIATRIC BRAIN TUMOR CHEMOTHERAPEUTIC EFFICACY
EXTH-18. PEPTIDE NANO-STRUCTURES ENHANCE PEDIATRIC BRAIN TUMOR CHEMOTHERAPEUTIC EFFICACY Open
Pediatric gliomas, particularly high-grade gliomas, which include diffuse intrinsic pontine gliomas (DIPGs), are among the most formidable and devastating cancers in children. These tumors remain incurable, despite many treatment approache…
View article: Reversible self-assembly of superstructured networks
Reversible self-assembly of superstructured networks Open
Chemically reversible hydrogels The dynamic reorganization of some cellular biopolymers in response to signals has inspired efforts to create artificial materials with similar properties. Freeman et al. created hydrogels based on peptide a…
View article: Cover Image, Volume 12, Issue 6
Cover Image, Volume 12, Issue 6 Open
The cover image, by Jacqueline J. Greene et al., is based on the Research Article Electrophysiological assessment of a peptide amphiphile nanofiber nerve graft for facial nerve repair, https://doi.org/10.1002/term.2669
View article: Electrophysiological assessment of a peptide amphiphile nanofiber nerve graft for facial nerve repair
Electrophysiological assessment of a peptide amphiphile nanofiber nerve graft for facial nerve repair Open
Facial nerve injury can cause severe long-term physical and psychological morbidity. There are limited repair options for an acutely transected facial nerve not amenable to primary neurorrhaphy. We hypothesize that a peptide amphiphile nan…
View article: Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation
Injectable biomimetic liquid crystalline scaffolds enhance muscle stem cell transplantation Open
Significance Most research aiming to achieve muscle regeneration focuses on the biology of “muscle stem cells,” but delivery methods that enhance transplantation efficiency of these cells are at early stages. We report on a liquid crystall…
View article: Sulfated glycopeptide nanostructures for multipotent protein activation
Sulfated glycopeptide nanostructures for multipotent protein activation Open
View article: Peptide Amphiphile Nanogel as an Improved BMP-2 Carrier for Spinal Arthrodesis
Peptide Amphiphile Nanogel as an Improved BMP-2 Carrier for Spinal Arthrodesis Open
Introduction Advances in biologics have led to improvements in spine fusion rates, but a commercially available bone graft substitute that elicits high bony fusion rates with minimal adverse effects is yet to be developed. Recombinant huma…
View article: Neural cell looking for friends
Neural cell looking for friends Open
2016 Fifth Place
View article: Correction to Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization <i>in Vivo</i>
Correction to Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization <i>in Vivo</i> Open
ADVERTISEMENT RETURN TO ISSUEPREVAdditions and Correc...Additions and CorrectionsORIGINAL ARTICLEThis notice is a correctionCorrection to Gd(III)-Labeled Peptide Nanofibers for Reporting on Biomaterial Localization in VivoAdam T. Preslar, …