Mark McLean
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View article: Dietary Habits in Early Pregnancy in a Multi-Ethnic Population: Results from the PROMOTE Cohort Study
Dietary Habits in Early Pregnancy in a Multi-Ethnic Population: Results from the PROMOTE Cohort Study Open
Introduction: The PROMOTE cohort study is a prospective pregnancy cohort study that seeks to improve the understanding of cardiometabolic risk and determinants, such as diet, during pregnancy in a multi-ethnic population. Increasing age an…
View article: Association Between Intensity of Physical Activity in Pregnancy and Gestational Diabetes in a Multi-Ethnic Population: Results from the PROMOTE Cohort Study
Association Between Intensity of Physical Activity in Pregnancy and Gestational Diabetes in a Multi-Ethnic Population: Results from the PROMOTE Cohort Study Open
Introduction: The demographic shift amongst pregnant women, including older age and increasing obesity, has resulted in an increased risk of cardiometabolic complications during pregnancy, particularly gestational diabetes. This paper pres…
View article: Assessing the clinical application of the PANOMEN 3 classification in a large cohort of pituitary tumors
Assessing the clinical application of the PANOMEN 3 classification in a large cohort of pituitary tumors Open
Objective Pituitary tumors are a heterogeneous group of neoplasms exhibiting a wide range of clinical and histological features. There are currently no comprehensive clinically validated prognostic tools to guide management of all tumor ty…
View article: Should we treat mild gestational diabetes? An Australian multicentre retrospective cohort study
Should we treat mild gestational diabetes? An Australian multicentre retrospective cohort study Open
Aims The International Association of Diabetes in Pregnancy Study Groups (IADPSG) diagnostic criteria for gestational diabetes (GDM) were widely implemented in Australia, despite limited evidence of better pregnancy outcomes compared to th…
View article: <b>The association between glycemia, glycemic variability and pregnancy complications in early GDM</b>
<b>The association between glycemia, glycemic variability and pregnancy complications in early GDM</b> Open
Objective: To investigate the association of timing of commencing glucose management with glycemia, glycemic variability, and pregnancy outcomes among women with early gestational diabetes mellitus (GDM).Research Design and Methods: A sub-…
View article: <b>The association between glycemia, glycemic variability and pregnancy complications in early GDM</b>
<b>The association between glycemia, glycemic variability and pregnancy complications in early GDM</b> Open
Objective: To investigate the association of timing of commencing glucose management with glycemia, glycemic variability, and pregnancy outcomes among women with early gestational diabetes mellitus (GDM).Research Design and Methods: A sub-…
View article: Ethnic Differences in Characteristics of Women Diagnosed With Early Gestational Diabetes: Findings From the TOBOGM Study
Ethnic Differences in Characteristics of Women Diagnosed With Early Gestational Diabetes: Findings From the TOBOGM Study Open
Objective To compare the prevalence and clinical characteristics of early gestational diabetes (eGDM) and associated birth outcomes among women of different ethnic groups. Methods This is a secondary analysis of an international, multicent…
View article: Effect of treatment for early gestational diabetes mellitus on neonatal respiratory distress: A secondary analysis of the <scp>TOBOGM</scp> study
Effect of treatment for early gestational diabetes mellitus on neonatal respiratory distress: A secondary analysis of the <span>TOBOGM</span> study Open
Objective To identify factors associated with neonatal respiratory distress (NRD) in early Gestational diabetes mellitus (eGDM). Design Nested case–control analysis of the TOBOGM trial. Setting Seventeen hospitals: Australia, Sweden, Austr…
View article: Relationship Between Early-Pregnancy Glycemia and Adverse Outcomes: Findings From the TOBOGM Study
Relationship Between Early-Pregnancy Glycemia and Adverse Outcomes: Findings From the TOBOGM Study Open
OBJECTIVE We evaluated associations between early-pregnancy oral glucose tolerance test (OGTT) glucose and complications in the Treatment of Booking Gestational Diabetes Mellitus (TOBOGM) cohort to inform prognostic OGTT thresholds. RESEAR…
View article: Relationship between early pregnancy glycemia and adverse outcomes: Findings from the TOBOGM Study
Relationship between early pregnancy glycemia and adverse outcomes: Findings from the TOBOGM Study Open
Objective We evaluated associations between early pregnancy OGTT glucose and complications in the Treatment of Booking Gestational Diabetes Mellitus (TOBOGM) cohort to inform prognostic OGTT thresholds. Research Design & Methods Individual…
View article: Relationship between early pregnancy glycemia and adverse outcomes: Findings from the TOBOGM Study
Relationship between early pregnancy glycemia and adverse outcomes: Findings from the TOBOGM Study Open
Objective We evaluated associations between early pregnancy OGTT glucose and complications in the Treatment of Booking Gestational Diabetes Mellitus (TOBOGM) cohort to inform prognostic OGTT thresholds. Research Design & Methods Individual…
View article: Cost-effectiveness of diagnosis and treatment of early gestational diabetes mellitus: economic evaluation of the TOBOGM study, an international multicenter randomized controlled trial
Cost-effectiveness of diagnosis and treatment of early gestational diabetes mellitus: economic evaluation of the TOBOGM study, an international multicenter randomized controlled trial Open
National Health and Medical Research Council (grants 1104231 and 2009326), Region O¨rebro Research Committee (grants Dnr OLL-970566 and OLL-942177), Medical Scientific Fund of the Mayor of Vienna (project 15,205 and project 23,026), South …
View article: Randomised Controlled Trial of a Customised Text Messaging and Activity Monitor Program for Lifestyle Improvement after Gestational Diabetes
Randomised Controlled Trial of a Customised Text Messaging and Activity Monitor Program for Lifestyle Improvement after Gestational Diabetes Open
Gestational diabetes (GDM) is associated with a long-term risk of diabetes. We aimed to determine whether a text-messaging-based lifestyle support program would improve diabetes risk factors following GDM. Women with GDM were randomised fo…
View article: Perinatal Outcomes in Early and Late Gestational Diabetes Mellitus After Treatment from 24-28 weeks’ Gestation: A TOBOGM Secondary Analysis
Perinatal Outcomes in Early and Late Gestational Diabetes Mellitus After Treatment from 24-28 weeks’ Gestation: A TOBOGM Secondary Analysis Open
Objective Most gestational diabetes mellitus (GDM) studies have combined women whether or not hyperglycemia was present earlier in pregnancy. This study compared perinatal outcomes between women with early GDM (EGDM: diagnosed
View article: Perinatal Outcomes in Early and Late Gestational Diabetes Mellitus After Treatment from 24-28 weeks’ Gestation: A TOBOGM Secondary Analysis
Perinatal Outcomes in Early and Late Gestational Diabetes Mellitus After Treatment from 24-28 weeks’ Gestation: A TOBOGM Secondary Analysis Open
Objective Most gestational diabetes mellitus (GDM) studies have combined women whether or not hyperglycemia was present earlier in pregnancy. This study compared perinatal outcomes between women with early GDM (EGDM: diagnosed
View article: Somatostatin receptor expression and clinical outcome of multilineage pituitary tumours expressing PIT1 and SF1
Somatostatin receptor expression and clinical outcome of multilineage pituitary tumours expressing PIT1 and SF1 Open
The application of transcription factor immunohistochemistry to pituitary neuroendocrine tumour (PitNET) assessment has allowed identification of tumours that do not conform to a single lineage. Multilineage pituitary transcription factor …
View article: Gromov-Witten invariants in complex and Morava-local $K$-theories
Gromov-Witten invariants in complex and Morava-local $K$-theories Open
Given a closed symplectic manifold $X$, we construct Gromov-Witten-type invariants valued both in (complex) $K$-theory and in any complex-oriented cohomology theory $\mathbb{K}$ which is $K_p(n)$-local for some Morava $K$-theory $K_p(n)$. …
View article: The relationship between body mass index and sleep in women with risk factors for gestational diabetes mellitus
The relationship between body mass index and sleep in women with risk factors for gestational diabetes mellitus Open
Background Both obesity and sleep disorders are common among women during pregnancy. Although prior research has identified a relationship between obesity and sleep disorders, those findings are from women later in pregnancy. Objective To …
View article: Aneurysmal subarachnoid haemorrhage in the pituitary fossa of a patient with acromegaly – a rare phenomenon
Aneurysmal subarachnoid haemorrhage in the pituitary fossa of a patient with acromegaly – a rare phenomenon Open
Summary The anatomy of the pituitary fossa is complex. The wall of the fossa can vary, resulting in inconsistencies in the nature and integrity of the sella barrier. Cerebrospinal fluid is generally confined to the subarachnoid space and d…
View article: The relationship between falling insulin requirements and serial ultrasound measurements in women with preexisting diabetes: a prospective cohort study
The relationship between falling insulin requirements and serial ultrasound measurements in women with preexisting diabetes: a prospective cohort study Open
A large fall in insulin requirements (FIR) in women with diabetes is associated with adverse clinical outcomes but previous studies have not examined its relation with serial ultrasound parameters. To determine whether FIR is associated wi…
View article: Insulin-like growth factor role in determining the anti-cancer effect of metformin: RCT in prostate cancer patients
Insulin-like growth factor role in determining the anti-cancer effect of metformin: RCT in prostate cancer patients Open
Objective Androgen deprivation therapy (ADT), a principal therapy in patients with prostate cancer, is associated with the development of obesity, insulin resistance, and hyperinsulinemia. Recent evidence indicates that metformin may slow …
View article: Normal Crossings Singularities for Symplectic Topology: Structures
Normal Crossings Singularities for Symplectic Topology: Structures Open
Our previous papers introduce topological notions of normal crossings symplectic divisor and variety, show that they are equivalent, in a suitable sense, to the corresponding geometric notions, and establish a topological smoothability cri…
View article: Effect of Maternal Metformin Treatment in Pregnancy on Neonatal Metabolism: Evidence From Newborn Metabolic Screening
Effect of Maternal Metformin Treatment in Pregnancy on Neonatal Metabolism: Evidence From Newborn Metabolic Screening Open
OBJECTIVE To investigate effects of maternal diabetes and metformin treatment on metabolic newborn screening (NBS) results of infants born to mothers with hyperglycemia during pregnancy. RESEARCH DESIGN AND METHODS Retrospective case-contr…
View article: Effect of Maternal Metformin Treatment in Pregnancy on Neonatal Metabolism: Evidence From Newborn Metabolic Screening
Effect of Maternal Metformin Treatment in Pregnancy on Neonatal Metabolism: Evidence From Newborn Metabolic Screening Open
Objective: To investigate effects of maternal diabetes and metformin treatment on metabolic newborn screening (NBS) results of infants born to mothers with hyperglycemia during pregnancy Research Design and Methods: Retrospective case-con…
View article: Effect of Maternal Metformin Treatment in Pregnancy on Neonatal Metabolism: Evidence From Newborn Metabolic Screening
Effect of Maternal Metformin Treatment in Pregnancy on Neonatal Metabolism: Evidence From Newborn Metabolic Screening Open
Objective: To investigate effects of maternal diabetes and metformin treatment on metabolic newborn screening (NBS) results of infants born to mothers with hyperglycemia during pregnancy Research Design and Methods: Retrospective case-con…
View article: A retrospective case‐control cohort analysis of comorbidity and health expenditure in hospitalized adults diagnosed with obesity utilizing <scp>ICD</scp>‐10 diagnostic coding
A retrospective case‐control cohort analysis of comorbidity and health expenditure in hospitalized adults diagnosed with obesity utilizing <span>ICD</span>‐10 diagnostic coding Open
Summary The cost and comorbidity of obesity in hospitalized inpatients, is less known. A retrospective study of patients presenting to a large district hospital in Western Sydney (April 2016‐February 2017) using clinical, pathological as w…
View article: Classifying Sequences of Extreme Length with Constant Memory Applied to\n Malware Detection
Classifying Sequences of Extreme Length with Constant Memory Applied to\n Malware Detection Open
Recent works within machine learning have been tackling inputs of\never-increasing size, with cybersecurity presenting sequence classification\nproblems of particularly extreme lengths. In the case of Windows executable\nmalware detection,…
View article: Androgen deprivation in prostate cancer: benefits of home-based resistance training
Androgen deprivation in prostate cancer: benefits of home-based resistance training Open
Introduction Androgen deprivation therapy (ADT) has detrimental effects on body composition, metabolic health, physical functioning, bone mineral density (BMD) and health-related quality of life (HRQOL) in men with prostate cancer. We inve…