Mark Milhaven
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View article: Interpreting Patterns of X Chromosomal Relative to Autosomal Diversity in Aye‐Ayes ( <i>Daubentonia madagascariensis</i> )
Interpreting Patterns of X Chromosomal Relative to Autosomal Diversity in Aye‐Ayes ( <i>Daubentonia madagascariensis</i> ) Open
We here present high‐quality, population‐level sequencing data from the X chromosome of the highly‐endangered aye‐aye, Daubentonia madagascariensis . Using both polymorphism‐ and divergence‐based inference approaches, we quantify fine‐scal…
View article: Interpreting patterns of X chromosomal relative to autosomal diversity in aye-ayes (<i>Daubentonia madagascariensis</i>)
Interpreting patterns of X chromosomal relative to autosomal diversity in aye-ayes (<i>Daubentonia madagascariensis</i>) Open
We here present high-quality, population-level sequencing data from the X chromosome of the highly-endangered aye-aye, Daubentonia madagascariensis . Using both polymorphism- and divergence-based inference approaches, we quantify fine-scal…
View article: Complete genome sequence of the <i>Streptomyces</i> bacteriophage Amabiko
Complete genome sequence of the <i>Streptomyces</i> bacteriophage Amabiko Open
Amabiko is a lytic subcluster BE2 bacteriophage that infects Streptomyces scabiei —a bacterium causing common scab in potatoes. Its 131,414 bp genome has a GC content of 49.5% and contains 245 putative protein-coding genes, 45 tRNAs, and o…
View article: Complete Genome Sequence of the <i>Microbacterium</i> Bacteriophage Chako
Complete Genome Sequence of the <i>Microbacterium</i> Bacteriophage Chako Open
We characterized the complete genome sequence of Chako, an obligate lytic bacteriophage with siphovirus morphology from subcluster EA1 that infects Microbacterium foliorum NRRL B-24224. Its 41.6-kb genome contains 62 putative protein-codin…
View article: Microbacterium Cluster EA Bacteriophages: Phylogenomic Relationships and Host Range Predictions
Microbacterium Cluster EA Bacteriophages: Phylogenomic Relationships and Host Range Predictions Open
Bacteriophages are being widely harnessed as an alternative to antibiotics due to the global emergence of drug-resistant pathogens. To guide the usage of these bactericidal agents, characterization of their host specificity is vital—howeve…
View article: Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution Open
We perform an extensive genomic analysis of freshwater adaption in threespine stickleback to predict evolution in other species.
View article: Complete Genome Sequence of <i>Microbacterium</i> Bacteriophage Erla
Complete Genome Sequence of <i>Microbacterium</i> Bacteriophage Erla Open
We characterized the complete genome sequence of Siphoviridae bacteriophage Erla, an obligatory lytic subcluster EA1 bacteriophage infecting Microbacterium foliorum NRRL B-24224, with a capsid width of 65 nm and a tail length of 112 nm. Th…
View article: Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution Open
Similar forms often evolve repeatedly in nature, raising longstanding questions about the underlying mechanisms. Here we use repeated evolution in sticklebacks to identify a large set of genomic loci that change recurrently during coloniza…
View article: Co-option of the lineage-specific <i>LAVA</i> retrotransposon in the gibbon genome
Co-option of the lineage-specific <i>LAVA</i> retrotransposon in the gibbon genome Open
Significance Transposable elements (TEs) are genetic units that can selfishly propagate in a host genome. Despite often being considered “junk,” TEs can occasionally acquire useful functions such as regulating expression of nearby host gen…
View article: Co-option of the gibbon-specific LAVA retrotransposon in DNA repair pathways [preprint]
Co-option of the gibbon-specific LAVA retrotransposon in DNA repair pathways [preprint] Open
Transposable elements (TEs) can shape gene regulation networks by being co-opted as enhancers. However, the contribution of lineage-specific TE insertions to recent adaptations remains poorly understood. Gibbons present a suitable model to…