Mark R. Marshall
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View article: Clinical study report data did not substantially alter point estimates but improved precision in a nephrology systematic review
Clinical study report data did not substantially alter point estimates but improved precision in a nephrology systematic review Open
When researchers want to understand how well a treatment works, they often combine results from several clinical studies in a process called a meta-analysis. Usually, these analyses rely on data published in scientific journals. However, p…
View article: Safety, efficacy, and immunogenicity of a novel IgG degrading enzyme (KJ103): results from two randomised, blinded, phase 1 clinical trials
Safety, efficacy, and immunogenicity of a novel IgG degrading enzyme (KJ103): results from two randomised, blinded, phase 1 clinical trials Open
The approved intravenous adeno-associated virus (AAV) therapies are limited by the widespread prevalence of pre-existing anti-AAV antibodies in the general population, which are known to restrict patients' ability to receive gene therapy a…
View article: Structural Equation Modelling to Identify Psychometric Determinants of Medication Adherence in a Survey of Kidney Dialysis Patients
Structural Equation Modelling to Identify Psychometric Determinants of Medication Adherence in a Survey of Kidney Dialysis Patients Open
Interventions that reduce patients' concerns about their medications are likely to improve adherence, rather than interventions that increase patients' perceived necessity for medication. Improving patients' general health literacy and fac…
View article: Peritoneal Dialysis (PD) Patient and Nurse Preferences around Novel and Standard Automated PD Device Features
Peritoneal Dialysis (PD) Patient and Nurse Preferences around Novel and Standard Automated PD Device Features Open
Key Points Adoption and extended time on peritoneal dialysis require patient input across a spectrum of needs, including automated PD (APD) device usability features that are less intimidating to patients and enable lifestyle advantages. A…
View article: Effect of Dialysate and Plasma Sodium on Mortality in a Global Historical Hemodialysis Cohort
Effect of Dialysate and Plasma Sodium on Mortality in a Global Historical Hemodialysis Cohort Open
Significance Statement This large observational cohort study aimed to investigate the relationship between dialysate and plasma sodium concentrations and mortality among maintenance hemodialysis patients. Using a large multinational cohort…
View article: THE MICROWAVE SPECTRA AND ROTAMER-DEPENDENT STRUCTURES OF THE GAS-PHASE HETERODIMERS FORMED BETWEEN 2,3,3-TRIFLUOROPROPENE AND ACETYLENE
THE MICROWAVE SPECTRA AND ROTAMER-DEPENDENT STRUCTURES OF THE GAS-PHASE HETERODIMERS FORMED BETWEEN 2,3,3-TRIFLUOROPROPENE AND ACETYLENE Open
Rotation of the difluoromethyl group in 2,3,3-trifluoropropene results in three minima: a higher energy, achiral rotamer that contains a plane of symmetry and two equivalent, chiral lower-energy rotamers that form an enantiomeric pair.As r…
View article: THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF THE GAS-PHASE HETERODIMERS, (E)-1,2,3,3,3-PENTAFLUOROPROPENE-ARGON AND (E)-1,2,3,3,3-PENTAFLUOROPROPENE-ACETYLENE
THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF THE GAS-PHASE HETERODIMERS, (E)-1,2,3,3,3-PENTAFLUOROPROPENE-ARGON AND (E)-1,2,3,3,3-PENTAFLUOROPROPENE-ACETYLENE Open
E)-1,2,3,3,3-pentafluoropene results from the formal replacement of one of the two geminal fluorine atoms in 1,1,2trifluoroethylene (the one located cis to the fluorine on the singly halogenated carbon) with a trifluoromethyl group.As dete…
View article: Simplified calculation of month-on-month annualized peritoneal dialysis associated peritonitis rate – Validation in ANZDATA, NZ PD and RDPLF registries
Simplified calculation of month-on-month annualized peritoneal dialysis associated peritonitis rate – Validation in ANZDATA, NZ PD and RDPLF registries Open
Peritonitis is the most important therapy-related complication of peritoneal dialysis (PD). Monthly or quarterly PD peritonitis rate statistics are used to identify special cause variation within or between individual PD centres, to highli…
View article: Table of contents
Table of contents Open
View article: A NOVEL STRUCTURE FOR THE GAS PHASE HETERODIMER FORMED BETWEEN (Z)-1-CHLORO-3,3,3-TRIFLUOROPROPENE AND ACETYLENE
A NOVEL STRUCTURE FOR THE GAS PHASE HETERODIMER FORMED BETWEEN (Z)-1-CHLORO-3,3,3-TRIFLUOROPROPENE AND ACETYLENE Open
View article: THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF THE CHIRAL TAGGING CANDIDATE CIS-1,3,3,3-TETRAFLUORO-1,2-EPOXYPROPANE AND ITS GAS PHASE HETERODIMER WITH THE ARGON ATOM
THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF THE CHIRAL TAGGING CANDIDATE CIS-1,3,3,3-TETRAFLUORO-1,2-EPOXYPROPANE AND ITS GAS PHASE HETERODIMER WITH THE ARGON ATOM Open
View article: THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF CIS- and TRANS-1,1,1-TRIFLUORO-2,3-EPOXYBUTANE
THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF CIS- and TRANS-1,1,1-TRIFLUORO-2,3-EPOXYBUTANE Open
View article: THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF THE CHIRAL AND ACHIRAL ROTAMERS OF 2,3,3-TRIFLUOROPROPENE AND THEIR GAS PHASE HETERODIMERS WITH THE ARGON ATOM
THE MICROWAVE SPECTRA AND MOLECULAR STRUCTURES OF THE CHIRAL AND ACHIRAL ROTAMERS OF 2,3,3-TRIFLUOROPROPENE AND THEIR GAS PHASE HETERODIMERS WITH THE ARGON ATOM Open
View article: Peritoneal Dialysis Associated Peritonitis Rate – Validation of a Simplified Formula
Peritoneal Dialysis Associated Peritonitis Rate – Validation of a Simplified Formula Open
Peritonitis is the most important therapy-related complication of peritoneal dialysis (PD). Unfortunately, many PD centers around the world do not accurately record peritonitis rate, mainly because they cannot ascertain PD patient time-at-…
View article: Table of contents
Table of contents Open
View article: Home Versus Facility Dialysis and Mortality in Australia and New Zealand
Home Versus Facility Dialysis and Mortality in Australia and New Zealand Open
The survival of patients on PD in 2013-2017 appears greater than the survival for patients on facility HD in ANZ. Additional research is needed to assess whether changing clinical risk profiles over time, varied dialysis prescription, and …
View article: A systematic review of peritoneal dialysis-related peritonitis rates over time from national or regional population-based registries and databases
A systematic review of peritoneal dialysis-related peritonitis rates over time from national or regional population-based registries and databases Open
Peritoneal dialysis (PD)-related peritonitis is one of the top priorities for care and research among PD stakeholders. This study summarizes PD peritonitis rates from available population-based national or regional registries around the wo…
View article: Non-polyvinyl chloride peritoneal dialysis sets: A double-edged sword?
Non-polyvinyl chloride peritoneal dialysis sets: A double-edged sword? Open
View article: Relationship between measured and prescribed dialysate sodium in haemodialysis: a systematic review and meta-analysis
Relationship between measured and prescribed dialysate sodium in haemodialysis: a systematic review and meta-analysis Open
Background Dialysate sodium (DNa) prescription policy differs between haemodialysis (HD) units, and the optimal DNa remains uncertain. We sought to summarize the evidence on the agreement between prescribed and delivered DNa, and whether t…
View article: Temporal changes in dialysate [Na<sup>+</sup>] prescription from 1996 to 2018 and their clinical significance as judged from a meta‐regression of clinical trials
Temporal changes in dialysate [Na<sup>+</sup>] prescription from 1996 to 2018 and their clinical significance as judged from a meta‐regression of clinical trials Open
Over the last two decades, the clinical care of dialysis patients has refocused sharply on fluid volume control. Dialysate [Na + ] is a key, albeit under‐investigated, clinical tool for manipulation of fluid volume on dialysis. In the arti…
View article: Early use of endotoxin absorption by oXiris in abdominal septic shock
Early use of endotoxin absorption by oXiris in abdominal septic shock Open
Rationale: Septic shock leads to multiple organ failure and increases mortality rate. We reported a critical patient with abdominal septic shock, which was the first case successfully treated with continuous renal replacement therapy (CRRT…
View article: Effect of Low-Sodium versus Conventional Sodium Dialysate on Left Ventricular Mass in Home and Self-Care Satellite Facility Hemodialysis Patients: A Randomized Clinical Trial
Effect of Low-Sodium versus Conventional Sodium Dialysate on Left Ventricular Mass in Home and Self-Care Satellite Facility Hemodialysis Patients: A Randomized Clinical Trial Open
Significance Statement Because fluid overload in patients undergoing hemodialysis contributes to cardiovascular morbidity and mortality, there is a global trend to use low-sodium dialysate in hemodialysis with the goal of reducing fluid ov…
View article: SUN-187 MORTALITY RISK BY DIALYSIS MODALITY OVER 1997 TO 2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION
SUN-187 MORTALITY RISK BY DIALYSIS MODALITY OVER 1997 TO 2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION Open
The relationship between mortality risk and modality can vary by era. We recently showed that improvements in mortality risk on home hemodialysis (HD) and peritoneal dialysis (PD) are outpacing those on facility HD in Australia and New Zea…
View article: SUN-189 MORTALITY RISK FOR PERITONEAL DIALYSIS (PD) VERSUS FACILITY HEMODIALYSIS (HD) IN PATIENTS &gt;65 YEARS OVER 1997-2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION
SUN-189 MORTALITY RISK FOR PERITONEAL DIALYSIS (PD) VERSUS FACILITY HEMODIALYSIS (HD) IN PATIENTS >65 YEARS OVER 1997-2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION Open
Older literature suggests that mortality risk in elderly patients is higher on PD compared to HD. However, more recent literature from numerous health jurisdictions suggest that the overall mortality risk on PD is improving compared to tha…
View article: SUN-190 MORTALITY RISK FOR PERITONEAL DIALYSIS (PD) VERSUS FACILITY HEMODIALYSIS (HD) IN PATIENTS BY CO-MORBIDITY STATUS FROM 1998-2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION
SUN-190 MORTALITY RISK FOR PERITONEAL DIALYSIS (PD) VERSUS FACILITY HEMODIALYSIS (HD) IN PATIENTS BY CO-MORBIDITY STATUS FROM 1998-2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION Open
Older literature suggests that mortality risk in patients with medical co-morbidity is higher on PD compared to HD. However, more recent literature from numerous health jurisdictions suggest that the overall mortality risk on PD is improvi…
View article: SUN-188 PATIENT MORTALITY RISK FOR PERITONEAL DIALYSIS (PD) VERSUS FACILITY HEMODIALYSIS (HD) BY DIABETES MELLITUS STATUS OVER 1997-2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION
SUN-188 PATIENT MORTALITY RISK FOR PERITONEAL DIALYSIS (PD) VERSUS FACILITY HEMODIALYSIS (HD) BY DIABETES MELLITUS STATUS OVER 1997-2017 IN THE AUSTRALIAN AND NEW ZEALAND DIALYSIS POPULATION Open
Older literature suggests that mortality risk in patients with diabetes mellitus is higher on PD compared to HD. However, more recent literature from numerous health jurisdictions suggest that the overall mortality risk on PD is improving …
View article: SAT-270 RISK OF PERITONEAL DIALYSIS (PD) - RELATED PERITONITIS WITH EXTERNAL CLAMP VERSUS INTERNAL SWITCH CONNECTOLOGY: A SYSTEMATIC SCOPING REVIEW
SAT-270 RISK OF PERITONEAL DIALYSIS (PD) - RELATED PERITONITIS WITH EXTERNAL CLAMP VERSUS INTERNAL SWITCH CONNECTOLOGY: A SYSTEMATIC SCOPING REVIEW Open
Approximately 6-11% of PD patients with peritonitis die of overwhelming infection during the episode itself, and approximately 2-3 fold more die if one includes deaths in the 30 days immediately afterwards. Overall, peritonitis is a major …
View article: The benefit of early survival on PD versus HD—Why this is (still) very important
The benefit of early survival on PD versus HD—Why this is (still) very important Open
There are a number of misconceptions around the identified early survival benefit of peritoneal dialysis (PD) relative to hemodialysis (HD), including that such benefits “even out in the end” since the relative risk of death over time even…
View article: Treatment of lead and arsenic poisoning in anuric patients – a case report and narrative review of the literature
Treatment of lead and arsenic poisoning in anuric patients – a case report and narrative review of the literature Open
View article: SUN-074 Icodextrin- vs. Either Single or Dual Compartment Glucose-Based Solutions for Peritoneal Dialysis – A Systematic Review and Meta-Analysis
SUN-074 Icodextrin- vs. Either Single or Dual Compartment Glucose-Based Solutions for Peritoneal Dialysis – A Systematic Review and Meta-Analysis Open
Patients with end-stage renal disease (ESRD) undergoing peritoneal dialysis (PD) have options regarding the osmotic agents used in PD fluids (PDFs). These include hyper-osmolar glucose, as well as iso-osmolar icodextrin, a soluble glucose …