Explanipedia

Community Knowledge, Attitudes and Preventive Behaviour Towards the Cardiovascular Benefits of Reduced Exposure to Air Pollution in Nigeria: Evidence from the CARDINAL Study Open

Adekunle Fakunle, Temilade Bello, Akintayo Olamide Ogunwale, Oyewale Mayowa Morakinyo, Olubunmi Ayinde , et al. · 2025

Background: Air pollution has emerged as a known risk factor for cardiovascular diseases (CVDs) globally. Raising public knowledge of the importance of air pollution exposure is crucial for implementing future interventions to improve card…

Preventing gambling‑related harm in adolescents: a pilot cluster randomized controlled trial Open

Fiona Dobbie, Mark R. Miller, Alastair Niven, Heather Wardle, Christopher J. Weir , et al. · 2025

Introduction PRoGRAM-A (Preventing Gambling Related Harm in Adolescents) is a peer-led, social network intervention to protect young people, their friends and family members from gambling related harm (GRH), through student led message dif…

A comprehensive review/expert statement on environmental risk factors of cardiovascular disease Open

Thomas Muenzel, Mette Sørensen, Jos Lelieveld, Philip J. Landrigan, Marin Kuntić , et al. · 2025

Cardiovascular disease (CVD) is the leading cause of mortality globally, with over 20 million deaths each year. While traditional risk factors—such as hypertension, diabetes, smoking, and poor diet—are well-established, emerging evidence u…

Air pollution and atherosclerosis Open

Anusha N. Seneviratne, Mark R. Miller · 2025

Air pollution is associated with considerable cardiovascular mortality and morbidity. The vascular disease atherosclerosis underlies many cardiovascular conditions, with atherosclerotic plaque rupture being a trigger for stroke and myocard…

Environmental modulators of vascular physiology and inflammation Open

Anusha N. Seneviratne, Anne Majumdar, Kalpana Surendranath, Mark R. Miller · 2025

Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environment…

Ten questions concerning the future of residential indoor air quality and its environmental justice implications Open

Douglas Booker, Giorgos Petrou, Lia Chatzidiakou, Dillip Kumar Das, Farooq Faheem , et al. · 2025

Public Health Communication and Trust: Opportunities for Understanding Open

Janel S. Schuh, Emma C. Prus, Cindy Abello, Katy M. Evans, Kathleen Walker , et al. · 2025

The COVID-19 pandemic highlighted the importance of effective communication to build and strengthen public trust in the field of public health. To address this need, we conducted virtual qualitative message testing via focus groups and ind…

The Impact of Air Pollution on Cardiovascular Health Outcomes in African Populations Open

Marvellous Adeoye, Shadi Rahimzadeh, Sean Taylor, Shreya Shrikhande, Pablo Perel , et al. · 2024

Clearing the Air to Address Pollution’s Cardiovascular Health Crisis Open

Mark R. Miller, Mariachiara Di Cesare, Shadi Rahimzadeh, Marvellous Adeoye, Pablo Perel , et al. · 2024

Air pollution is a critical global health issue that significantly impacts cardiovascular health. The air pollutant PM2.5 (particulate matter with a diameter of 2.5 micrometres or less) has been positioned as a leading environmental risk f…

Water, Soil, Noise, and Light Pollution Open

Mark R. Miller, Philip J. Landrigan, Manish Arora, David E. Newby, Thomas Münzel , et al. · 2024

Air pollution and myocardial infarction in Poland Open

Mark R. Miller · 2024

First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses Open

Jack Andrews, Shruti Joshi, Evangelos Tzolos, Maaz Syed, Hayley Cuthbert , et al. · 2024

Graphene oxide nanomaterials are being developed for wide-ranging applications but are associated with potential safety concerns for human health. We conducted a double-blind randomized controlled study to determine how the inhalation of g…

PAR4 Antagonism in Patients With Coronary Artery Disease Receiving Antiplatelet Therapies Open

Jennifer Nash, Mohammed N. Meah, Beth Whittington, Samuel Debono, Jennifer Raftis , et al. · 2024

BACKGROUND: BMS-986141 is a novel potent highly selective antagonist of PAR (protease-activated receptor) type 4. PAR4 antagonism has been demonstrated to reduce thrombus formation in isolation and in combination with factor Xa inhibition …

New insights into the association of air pollution and kidney diseases by tracing gold nanoparticles with inductively coupled plasma mass spectrometry Open

Souzana Angel, Lorna J. Eades, Gavin Sim, Alicja Czopek, Neeraj Dhaun , et al. · 2024

Exposure to particles from air pollution has been associated with kidney disease; however, the underlying biological mechanisms are incompletely understood. Inhaled particles can gain access to the circulation and, depending on their size,…

Cardiovascular disease in low- and middle-income countries associated with environmental factors Open

Karen Sliwa, Charle Viljoen, Simon Stewart, Mark R. Miller, Dorairaj Prabhakaran , et al. · 2024

There is a growing recognition that the profound environmental changes that have occurred over the past century pose threats to human health. Many of these environmental factors, including air pollution, noise pollution, as well as exposur…

More People, More Active, More Often for Heart Health – Taking Action on Physical Activity Open

Trevor Shilton, Adrian Bauman, Birgit Beger, Anna Chalkley, Beatriz Champagne , et al. · 2024

Physical inactivity is a leading contributor to increased cardiovascular morbidity and mortality. Almost 500 million new cases of preventable noncommunicable diseases (NCDs) will occur globally between 2020 and 2030 due to physical inactiv…

Heath Impact of Policies to Reduce Agriculture-Related Air Pollutants in the UK: The Relative Contribution of Change in Pm2.5 Exposure and Diets to Morbidity and Mortality Open

Silvia Pastorino, Ai Milojevic, Rosemary Green, Rachel Beck, Edward Carnell , et al. · 2024

Children are especially vulnerable to air pollution: we need data on transport emissions near schools Open

J. J. F. Belch, Andrew Elder, S.P. Bartlett, Tom Fardon, Kerry Flinn , et al. · 2023

Ambient air pollution and maternal cardiovascular health in pregnancy Open

Fabienne Decrue, Rosemary Townsend, Mark R. Miller, David E. Newby, Rebecca M. Reynolds · 2023

In this review, we summarise the current epidemiological and experimental evidence on the association of ambient (outdoor) air pollution exposure and maternal cardiovascular health during pregnancy. This topic is of utmost clinical and pub…

Cardiopulmonary benefits of respirator intervention against near road ambient particulate matters in healthy young adults: A randomized, blinded, crossover, multi-city study Open

Wei Niu, Wanzhou Wang, Chen Huang, Zhihong Zhang, Le Ma , et al. · 2022

A Review of Road Traffic-Derived Non-Exhaust Particles: Emissions, Physicochemical Characteristics, Health Risks, and Mitigation Measures Open

Julia C. Fussell, Meredith Franklin, David C. Green, Mats Gustafsson, Roy M. Harrison , et al. · 2022

Implementation of regulatory standards has reduced exhaust emissions of particulate matter from road traffic substantially in the developed world. However, nonexhaust particle emissions arising from the wear of brakes, tires, and the road …

Nitrate and nitrite contamination in drinking water and cancer risk: A systematic review with meta-analysis Open

Roberto Picetti, Megan Deeney, Silvia Pastorino, Mark R. Miller, Anoop Shah , et al. · 2022

We identified an association of nitrate in drinking water with gastric cancer but with no other cancer site. There is currently a paucity of robust studies from settings with high levels nitrate pollution in drinking water. Research into t…

Determining nanoform similarity via assessment of surface reactivity by abiotic and in vitro assays Open

Didem Ag Seleci, Georgia Tsiliki, Kai Werle, Derek Alexander Elam, Omena Okpowe , et al. · 2022

Grouping of substances is a method used to streamline hazard and risk assessment. Assessment of similarity provides the scientific evidence needed for formation of groups. This work reports on justification of grouping of nanoforms (NFs) v…

Air pollution and cardiovascular disease: the Paul Wood Lecture, British Cardiovascular Society 2021 Open

Shruti Joshi, Mark R. Miller, David E. Newby · 2022

Air pollution is associated with up to 8.8 million excess deaths worldwide each year and is a major contributor to the global burden of disease. Cardiovascular conditions are the predominant cause for air pollution-related deaths and there…

Exposure to Elevated Nitrogen Dioxide Concentrations and Cardiac Remodeling in Patients With Dilated Cardiomyopathy Open

Daniela Fecht, Marc Chadeau‐Hyam, Ruth Owen, John Gregson, Brian P. Halliday , et al. · 2022

Cardiopulmonary Benefits of Respirator Intervention Against Ambient Particulate Matters in Healthy Young Adults: A Randomized, Blinded, Crossover, Multi-City Study Open

Wei Niu, Wanzhou Wang, Chen Huang, Zhihong Zhang, Le Ma , et al. · 2022

The cardiovascular effects of air pollution: Prevention and reversal by pharmacological agents Open

Mark R. Miller · 2021

Acute cardiovascular effects of controlled exposure to dilute Petrodiesel and biodiesel exhaust in healthy volunteers: a crossover study Open

Jon Unosson, Mikael Kabéle, Christoffer Boman, Robin Nyström, Ioannis Sadiktsis , et al. · 2021

Atmospheric conditions and composition that influence PM <sub>2.5</sub> oxidative potential in Beijing, China Open

Steven J. Campbell, Kate Wolfer, Battist Utinger, Joe Westwood, Zhi-Hui Zhang , et al. · 2021

Epidemiological studies have consistently linked exposure to PM2.5 with adverse health effects. The oxidative potential (OP) of aerosol particles has been widely suggested as a measure of their potential toxicity. Several acellular chemica…

Changing the COVID-19 Conversation: It’s About Language Open

Mark R. Miller, Brian C. Castrucci · 2021

Nearly a year into a once-in-a-century pandemic, US leaders continue to struggle to communicate salient coronavirus disease 2019 (COVID-19) information that resonates with the public and builds trust in science.Contributing to this challen…

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