Mark Sedrak
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View article: Spine MRI Diverticular Patterns Predict CSF-Venous Fistula Location: A 100-Patient Study
Spine MRI Diverticular Patterns Predict CSF-Venous Fistula Location: A 100-Patient Study Open
CVF ＝ CSF-venous fistula; CTM ＝ CT myelogram.
View article: Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease
Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease Open
Importance The Implantable Neurostimulator for the Treatment of Parkinson’s Disease (INTREPID) trial was a randomized, double-blind, sham-controlled study of subthalamic nucleus (STN) deep brain stimulation (DBS) for the treatment of Parki…
View article: Decubitus Myelography for Spinal Extradural Arachnoid Cyst: Better Classified as a Lateral Dural CSF Leak?
Decubitus Myelography for Spinal Extradural Arachnoid Cyst: Better Classified as a Lateral Dural CSF Leak? Open
Spinal extradural arachnoid cysts are rare lesions that may result in compressive myelopathy. Their etiology is unclear, but they are thought to represent extradural collections due to a one-way dural defect from the subarachnoid space to …
View article: Phantom-Enhanced High Mechanical Accuracy for Frame-Based Deep Brain Stimulation
Phantom-Enhanced High Mechanical Accuracy for Frame-Based Deep Brain Stimulation Open
Deep brain stimulation (DBS) is a neurosurgical procedure that depends on high-accuracy targeting of structures to implant electrodes within the brain. The positioning of these electrodes in the brain determines the long-term efficacy of t…
View article: Motion Detection and Correction for Frame-Based Stereotactic Localization
Motion Detection and Correction for Frame-Based Stereotactic Localization Open
Frame-based stereotactic localization is an important step for targeting during a surgical procedure. The motion may cause artifacts in this step reducing the accuracy of surgical targeting. While modeling of motion in real-life scenarios …
View article: Spontaneous Spinal CSF Leaks Stratified by Age, Body Mass Index, and Spinal Level
Spontaneous Spinal CSF Leaks Stratified by Age, Body Mass Index, and Spinal Level Open
Type 1 CSF leaks occurred in younger patients with a normal body mass index, while patients with type 3 CSF leaks were relatively older and had an elevated body mass index. Type 1 leaks mostly occurred in the upper thoracic spine, and type…
View article: Stereotactic Localization: From Single-Slice to Multi-Slice Registration Including a Novel Solution for Parallel Bipanels
Stereotactic Localization: From Single-Slice to Multi-Slice Registration Including a Novel Solution for Parallel Bipanels Open
View article: The V-Localizer for Stereotactic Guidance
The V-Localizer for Stereotactic Guidance Open
Image-guidance for frame-based stereotaxis is facilitated by incorporating three to four N-localizers or Sturm-Pastyr localizers into a stereotactic frame. An extant frame that incorporates only two N-localizers violates the fundamental pr…
View article: Novel Geometries for Stereotactic Localizers
Novel Geometries for Stereotactic Localizers Open
The three proposed novel models meet our design objectives. Of the three, the Z-localizer produced the least propagation of error. The M-localizer was simpler and had slightly more error than the Z-localizer. The F-localizer produced more …
View article: Double blind randomized controlled trial of deep brain stimulation for obsessive-compulsive disorder: Clinical trial design
Double blind randomized controlled trial of deep brain stimulation for obsessive-compulsive disorder: Clinical trial design Open
Obsessive-compulsive disorder (OCD), a leading cause of disability, affects ~1-2% of the population, and can be distressing and disabling. About 1/3 of individuals demonstrate poor responsiveness to conventional treatments. A small proport…
View article: Monte Carlo Simulation of Errors for N-localizer Systems in Stereotactic Neurosurgery: Novel Proposals for Improvements
Monte Carlo Simulation of Errors for N-localizer Systems in Stereotactic Neurosurgery: Novel Proposals for Improvements Open
View article: Coordinate Systems for Navigating Stereotactic Space: How Not to Get Lost
Coordinate Systems for Navigating Stereotactic Space: How Not to Get Lost Open
All stereotactic neurosurgical procedures utilize coordinate systems to allow navigation through the brain to a target. During the surgical planning, indirect and direct targeting determines the planned target point and trajectory. This ta…
View article: Applied Mathematics of Ray Tracing and Perspective Projection in Fiducial-Based Registration of X-Ray Images
Applied Mathematics of Ray Tracing and Perspective Projection in Fiducial-Based Registration of X-Ray Images Open
View article: Outcomes of a Multicenter, Prospective, Crossover, Randomized Controlled Trial Evaluating Subperception Spinal Cord Stimulation at ≤1.2 kHz in Previously Implanted Subjects
Outcomes of a Multicenter, Prospective, Crossover, Randomized Controlled Trial Evaluating Subperception Spinal Cord Stimulation at ≤1.2 kHz in Previously Implanted Subjects Open