Mark Soffing
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View article: Evaluating the Combined Anticancer Response of Checkpoint Inhibitor Immunotherapy and FAP-Targeted Molecular Radiotherapy in Murine Models of Melanoma and Lung Cancer
Evaluating the Combined Anticancer Response of Checkpoint Inhibitor Immunotherapy and FAP-Targeted Molecular Radiotherapy in Murine Models of Melanoma and Lung Cancer Open
Immunotherapy has dramatically improved outcomes for some cancer patients; however, novel treatments are needed for more patients to achieve a long-lasting response. FAP-targeted molecular radiotherapy has shown efficacy in both preclinica…
View article: A randomized trial of blood donor iron repletion on red cell quality for transfusion and donor cognition and well-being
A randomized trial of blood donor iron repletion on red cell quality for transfusion and donor cognition and well-being Open
Although altruistic regular blood donors are vital for the blood supply, many become iron deficient from donation-induced iron loss. The effects of blood donation–induced iron deficiency on red cell transfusion quality or donor cognition a…
View article: Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion
Donor glucose-6-phosphate dehydrogenase deficiency decreases blood quality for transfusion Open
BACKGROUNDGlucose-6-phosphate dehydrogenase (G6PD) deficiency decreases the ability of red blood cells (RBCs) to withstand oxidative stress. Refrigerated storage of RBCs induces oxidative stress. We hypothesized that G6PD-deficient donor R…
View article: Prolonged red cell storage before transfusion increases extravascular hemolysis
Prolonged red cell storage before transfusion increases extravascular hemolysis Open
NIH grant HL115557 and UL1 TR000040.