Mark Tacey
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View article: Magnetic Resonance Guided Radiation Therapy ( <scp>MRgRT</scp> ) Prostate Motion and Margins
Magnetic Resonance Guided Radiation Therapy ( <span>MRgRT</span> ) Prostate Motion and Margins Open
Introduction Systematic and random errors in radiation dose delivery necessitate the use of planning target volume (PTV) margins to ensure adequate clinical target volume (CTV) treatment. Advances in magnetic resonance‐guided radiation the…
View article: Implementation evaluation of a comprehensive CARE record to reduce hospital-acquired complications: a mixed-methods pre–post study
Implementation evaluation of a comprehensive CARE record to reduce hospital-acquired complications: a mixed-methods pre–post study Open
Objectives To evaluate whether implementing the Comprehensive Assessment and Risk Evaluation (CARE) record, developed to operationalise Standard 5: Comprehensive Care of the Australian National Safety and Quality Health Service Standards w…
View article: Research motivators, barriers and progress of allied health clinicians engaged in an Allied Health Research Clinic. An observational study
Research motivators, barriers and progress of allied health clinicians engaged in an Allied Health Research Clinic. An observational study Open
Background Embedding evidence-based practice (EBP) into healthcare is essential to improving patient outcomes and workforce sustainability. Building research capacity among allied health professionals is a key strategy for strengthening EB…
View article: From Normal to Optimal: Investigating Metabolic and Inflammatory Parameters as Predictors of Survival in Locally Advanced Cervical Cancer
From Normal to Optimal: Investigating Metabolic and Inflammatory Parameters as Predictors of Survival in Locally Advanced Cervical Cancer Open
Cervical cancer is the third most common cancer in women, and recent studies have highlighted the importance of body composition markers in predicting patient outcomes. We build upon the data of 83 patients from the Uterus-11 study, to exp…
View article: Impact of a specialised pleural medicine unit in the management of pleural infection
Impact of a specialised pleural medicine unit in the management of pleural infection Open
Background Managing pleural infection can be complex and costly and demonstrates considerable healthcare utlilisation. Aims To describe the influence of a specialised pleural medicine unit (SPMU) on outcomes for people with pleural infecti…
View article: Magnetic resonance imaging-guided single-fraction preoperative radiotherapy for early-stage breast cancer (the RICE trial): feasibility study
Magnetic resonance imaging-guided single-fraction preoperative radiotherapy for early-stage breast cancer (the RICE trial): feasibility study Open
Background Over the past decade, the adoption of screening programs, digital mammography, and magnetic resonance imaging (MRI) has increased early-stage breast cancer diagnosis rates. Mortality rates have decreased due to early detection a…
View article: Magnetic Resonance Imaging-Guided Single-Fraction Preoperative Radiotherapy for Early Stage Breast Cancer (The RICE Trial): Feasibility Study
Magnetic Resonance Imaging-Guided Single-Fraction Preoperative Radiotherapy for Early Stage Breast Cancer (The RICE Trial): Feasibility Study Open
Background: Over the past decade, the adoption of screening programs, digital mammography, and Magnetic Resonance Imaging (MRI) has increased early-stage breast cancer diagnosis rates. Mortality rates have decreased due to early detection,…
View article: Study protocol for Optimising patient positioning for accelerated partial breast radiotherapy with the Integrated Magnetic Resonance Linear Accelerator -OPRAH MRL
Study protocol for Optimising patient positioning for accelerated partial breast radiotherapy with the Integrated Magnetic Resonance Linear Accelerator -OPRAH MRL Open
Background: Accelerated partial breast irradiation (APBI) is an accepted treatment option for early breast cancer. Treatment delivered on the Magnetic Resonance integrated Linear Accelerator (MRL) provides the added assurance of improved s…
View article: Magnetic Resonance Imaging-Guided Single-Fraction Preoperative Radiotherapy for Early Stage Breast Cancer (The RICE Trial): Feasibility Study
Magnetic Resonance Imaging-Guided Single-Fraction Preoperative Radiotherapy for Early Stage Breast Cancer (The RICE Trial): Feasibility Study Open
Background Over the past decade, the adoption of screening programs, digital mammography, and Magnetic Resonance Imaging (MRI) has increased early-stage breast cancer diagnosis rates. Mortality rates have decreased due to early detection, …
View article: A double‐blinded randomised controlled study of fluid restriction versus liberal fluid during induction of labour: A pilot study
A double‐blinded randomised controlled study of fluid restriction versus liberal fluid during induction of labour: A pilot study Open
Background Excess intravenous fluid for women requiring an induction of labour may adversely affect the duration of labour and maternal/neonatal outcomes. Aims This study aimed to determine the difference in duration of labour and outcomes…
View article: Temporal changes in toe-brachial index results in haemodialysis patients
Temporal changes in toe-brachial index results in haemodialysis patients Open
Introduction Toe brachial index (TBI), the ratio of toe pressure to systolic blood pressure (SBP), helps predict peripheral arterial disease. In patients with kidney failure this may be performed during haemodialysis for convenience. Until…
View article: Low-dose-rate brachytherapy and long-term treatment outcomes in patients younger than 60 years of age
Low-dose-rate brachytherapy and long-term treatment outcomes in patients younger than 60 years of age Open
With excellent long-term treatment outcomes and minimal associated toxicities, our results showed that LDR brachytherapy can be an effective treatment of choice in younger men.
View article: Multivariable risk model for postpartum re-presentation with hypertension: development phase
Multivariable risk model for postpartum re-presentation with hypertension: development phase Open
Objectives Postpartum hypertension is one of the leading causes of re-presentation to hospital postpartum and is associated with adverse long-term cardiovascular risk. Postpartum blood pressure monitoring and management interventions have …
View article: Ivabradine in the Prevention, and Reduction in Size, of Perioperative Myocardial Injury in Patients Undergoing Orthopedic Surgery for Acute Fracture
Ivabradine in the Prevention, and Reduction in Size, of Perioperative Myocardial Injury in Patients Undergoing Orthopedic Surgery for Acute Fracture Open
Background Perioperative myocardial injury is common after major noncardiac surgery and is associated with adverse outcomes. This study investigated the use of ivabradine in patients undergoing urgent surgery for fracture. Methods and Resu…
View article: Association between <scp>COVID</scp>‐19 vaccination and 28‐day all‐cause mortality in <scp>SARS‐CoV</scp>‐2–infected older people living in residential aged care facilities
Association between <span>COVID</span>‐19 vaccination and 28‐day all‐cause mortality in <span>SARS‐CoV</span>‐2–infected older people living in residential aged care facilities Open
This retrospective cross‐sectional study reviewed the association between COVID‐19 vaccination and the 28‐day all‐cause mortality amongst SARS‐CoV‐2–infected older people living in residential aged care facilities. A lower mortality rate w…
View article: Current state of radiomic research in pancreatic cancer: focusing on study design and reproducibility of findings
Current state of radiomic research in pancreatic cancer: focusing on study design and reproducibility of findings Open
Objectives To critically appraise methodology and reproducibility of published studies on CT radiomics of pancreatic ductal adenocarcinoma (PDAC). Methods PRISMA literature search of MEDLINE, PubMed, and Scopus databases was conducted from…
View article: A clinical study comparing polymer and gold fiducials for prostate cancer radiotherapy
A clinical study comparing polymer and gold fiducials for prostate cancer radiotherapy Open
Introduction Image guidance with gold fiducials improves outcomes of prostate radiotherapy. However, gold produces artefact on CT imaging, interfering with contouring and verification. The purpose of this study was to compare polymer to st…
View article: Practical Decision-Making in Regards to Colonoscopy following Admission for Acute Diverticulitis
Practical Decision-Making in Regards to Colonoscopy following Admission for Acute Diverticulitis Open
Objective: Patients with acute diverticulitis (AD) have an increased risk of underlying colorectal cancer (CRC), however those with uncomplicated AD may have the same underlying population risk. Despite evidence suggesting these patients m…
View article: An integrated interpreting service normalizes access to care for culturally and linguistically diverse (CALD) patients with colorectal cancer
An integrated interpreting service normalizes access to care for culturally and linguistically diverse (CALD) patients with colorectal cancer Open
Aim To compare access to the initial management and overall survival with colorectal cancer for limited English proficient (LEP) patients compared with patients from an English background. Methods All newly diagnosed patients from 2017 wit…
View article: Plasma Angiotensin Converting Enzyme 2 (ACE2) Activity in Healthy Controls and Patients with Cardiovascular Risk Factors and/or Disease
Plasma Angiotensin Converting Enzyme 2 (ACE2) Activity in Healthy Controls and Patients with Cardiovascular Risk Factors and/or Disease Open
Angiotensin converting enzyme 2 (ACE2) is an endogenous negative regulator of the renin-angiotensin system, a key factor in the development of cardiovascular disease (CVD). ACE2 is also used by SARS-CoV-2 for host cell entry. Given that CO…
View article: Correlating measured radiotherapy dose with patterns of endocrinopathy: The importance of minimizing pituitary dose
Correlating measured radiotherapy dose with patterns of endocrinopathy: The importance of minimizing pituitary dose Open
Background Pituitary insufficiency is a common toxicity of cranial radiotherapy received in childhood for central nervous system, head and neck, and hematological malignancies. There is a recognized deficiency pattern and correlation with …