Mark Wade
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View article: The Indirect Effect of a Brief Couple Intervention on Child Mental Health Challenges via the Interparental Relationship
The Indirect Effect of a Brief Couple Intervention on Child Mental Health Challenges via the Interparental Relationship Open
Background Child mental health challenges have long‐term implications for social and emotional functioning. The quality of the interparental relationship is an important contributor to children's mental health challenges. Evidence supports…
View article: Blunted stress reactivity as a mechanism linking early psychosocial deprivation to psychopathology during adolescence
Blunted stress reactivity as a mechanism linking early psychosocial deprivation to psychopathology during adolescence Open
View article: Author Correction: Blunted stress reactivity as a mechanism linking early psychosocial deprivation to psychopathology during adolescence
Author Correction: Blunted stress reactivity as a mechanism linking early psychosocial deprivation to psychopathology during adolescence Open
View article: Secondary benefits of a brief couples intervention on coparenting through relationship quality and partner conflict
Secondary benefits of a brief couples intervention on coparenting through relationship quality and partner conflict Open
In two‐parent households, the interparental relationship and coparenting alliance are central to the well‐being of family relationships and young children. The current study examines whether participation in a brief, online, couple‐focused…
View article: Associations between paternal and maternal attention deficit hyperactivity disorder and children’s socioemotional development during early childhood
Associations between paternal and maternal attention deficit hyperactivity disorder and children’s socioemotional development during early childhood Open
This study examined associations between paternal, maternal, and dual-parental attention deficit hyperactivity disorder (ADHD) symptoms and child socioemotional functioning over the first two years of life, combined and separated by child …
View article: Associations between self-reported ADHD symptoms and depression and anxiety in mothers and fathers during the postpartum period: A Canadian nationwide longitudinal study
Associations between self-reported ADHD symptoms and depression and anxiety in mothers and fathers during the postpartum period: A Canadian nationwide longitudinal study Open
Parental ADHD in the postpartum period is associated with depression and anxiety among mothers and fathers. Paternal ADHD was a risk for maternal mental health problems in the early postpartum period, and maternal ADHD was a risk for pater…
View article: Using Machine Learning to Identify Correlates of Youth Mental Health and Well-Being: A Cross-Sectional Population Study
Using Machine Learning to Identify Correlates of Youth Mental Health and Well-Being: A Cross-Sectional Population Study Open
View article: Dimensions of parenting during infancy: Testing a latent bifactor model
Dimensions of parenting during infancy: Testing a latent bifactor model Open
In the current paper, we examined the dimensional structure of parenting using a bifactor model of observed parenting domains during infancy. We validated our parenting dimensions by examining correlations with indicators of family well‐be…
View article: Interactions Between Early-Life Adversity, Pandemic Stress, and Social Support on Psychiatric Disorders in a Nationally Representative Sample of Canadian Adults
Interactions Between Early-Life Adversity, Pandemic Stress, and Social Support on Psychiatric Disorders in a Nationally Representative Sample of Canadian Adults Open
PURPOSE Mental health problems increased during the COVID-19 pandemic, but the interaction between pandemic stress, early-life adversity, and social support in predicting mental health is not well understood. This study examined independen…
View article: Linking caregiving quality during infancy to brain activity in early childhood and later executive function
Linking caregiving quality during infancy to brain activity in early childhood and later executive function Open
There is no relationship more vital than the one a child shares with their primary caregivers early in development. Yet many children worldwide are raised in settings that lack the warmth, connection, and stimulation provided by a responsi…
View article: A Pilot Randomized Controlled Trial of a Brief Conflict Reappraisal Intervention for Community Couples with Young Children
A Pilot Randomized Controlled Trial of a Brief Conflict Reappraisal Intervention for Community Couples with Young Children Open
Purpose: The Love Together, Parent Together (L2P2) program is a brief, online couple’s intervention designed to prevent relationship deterioration by targeting maladaptive psychological processes. Methods: The current study used a parallel…
View article: Parental mental health trajectories over the COVID-19 pandemic and links with childhood adversity and pandemic stress
Parental mental health trajectories over the COVID-19 pandemic and links with childhood adversity and pandemic stress Open
View article: Cognitive and Emotional Well-Being of Preschool Children Before and During the COVID-19 Pandemic
Cognitive and Emotional Well-Being of Preschool Children Before and During the COVID-19 Pandemic Open
Importance The association between COVID-19 social disruption and young children’s development is largely unknown. Objective To examine associations of pandemic exposure with neurocognitive and socioemotional development at 24 and 54 month…
View article: MPN-439 Preliminary Data From the Phase 1/2 Study of TP-3654, an Investigational Selective PIM1 Kinase Inhibitor, Showed Cytokine Reduction and Clinical Responses in Relapsed/Refractory Myelofibrosis (MF)
MPN-439 Preliminary Data From the Phase 1/2 Study of TP-3654, an Investigational Selective PIM1 Kinase Inhibitor, Showed Cytokine Reduction and Clinical Responses in Relapsed/Refractory Myelofibrosis (MF) Open
View article: P1031: PRELIMINARY DATA FROM THE PHASE 1/2 STUDY OF TP-3654, AN INVESTIGATIONAL SELECTIVE PIM1 KINASE INHIBITOR, SHOWED CYTOKINE REDUCTION AND CLINICAL RESPONSES IN RELAPSED/REFRACTORY MYELOFIBROSIS
P1031: PRELIMINARY DATA FROM THE PHASE 1/2 STUDY OF TP-3654, AN INVESTIGATIONAL SELECTIVE PIM1 KINASE INHIBITOR, SHOWED CYTOKINE REDUCTION AND CLINICAL RESPONSES IN RELAPSED/REFRACTORY MYELOFIBROSIS Open
Topic: 16. Myeloproliferative neoplasms - Clinical Background: The constitutively active PIM1 serine/threonine kinase is highly expressed in hematologic malignancies including myelofibrosis (MF) and has been shown to play a role in modulat…
View article: Structure of Psychopathology in Romanian Preschool-Aged Children in an Epidemiological and a High-Risk Sample
Structure of Psychopathology in Romanian Preschool-Aged Children in an Epidemiological and a High-Risk Sample Open
View article: Associations between EEG trajectories, family income, and cognitive abilities over the first two years of life
Associations between EEG trajectories, family income, and cognitive abilities over the first two years of life Open
View article: Neural Correlates of the p Factor in Adolescence: Cognitive Control With and Without Enhanced Positive Affective Demands
Neural Correlates of the p Factor in Adolescence: Cognitive Control With and Without Enhanced Positive Affective Demands Open
View article: Supplementary Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
Supplementary Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention Open
Supplementary Data from Use of Oral N-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
View article: Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention Open
Purpose: Induction of oxidative stress has been implicated in UV-induced melanoma. We sought to determine whether the antioxidant N-acetylcysteine (NAC) could be safely administered to protect melanocytic nevi from the oxidat…
View article: Supplementary Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
Supplementary Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention Open
Supplementary Data from Use of Oral N-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
View article: Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention
Data from Use of Oral <i>N</i>-Acetylcysteine for Protection of Melanocytic Nevi against UV-Induced Oxidative Stress: Towards a Novel Paradigm for Melanoma Chemoprevention Open
Purpose: Induction of oxidative stress has been implicated in UV-induced melanoma. We sought to determine whether the antioxidant N-acetylcysteine (NAC) could be safely administered to protect melanocytic nevi from the oxidat…
View article: Cohort profile: Impact of Maternal and Paternal Mental Health – Assessing Concurrent Depression, Anxiety and Comorbidity in the Canadian Family (IMPACT study)
Cohort profile: Impact of Maternal and Paternal Mental Health – Assessing Concurrent Depression, Anxiety and Comorbidity in the Canadian Family (IMPACT study) Open
Purpose This paper describes a prospective cohort, Impact of Maternal and Paternal Mental Health: Assessing Concurrent Depression, Anxiety and Comorbidity in The Canadian Family (IMPACT) study, which followed maternal–paternal dyads and th…
View article: Why we still need longitudinal mental health research with children and youth during (and after) the COVID-19 pandemic
Why we still need longitudinal mental health research with children and youth during (and after) the COVID-19 pandemic Open
View article: Associations between EEG trajectories, family income, and cognitive abilities over the first two years of life.
Associations between EEG trajectories, family income, and cognitive abilities over the first two years of life. Open
We sought to characterize developmental trajectories of EEG spectral power over the first 2 years after birth and examine whether family income or maternal education alter those trajectories. We analyzed EEGs (n=161 infants, 534 EEGs) coll…
View article: Associations between Eeg Trajectories, Family Income, And Cognitive Abilities Over the First Two Years of Life
Associations between Eeg Trajectories, Family Income, And Cognitive Abilities Over the First Two Years of Life Open
View article: Latent Classes of Adverse and Benevolent Childhood Experiences in a Multinational Sample of Parents and Their Relation to Parent, Child, and Family Functioning during the COVID-19 Pandemic
Latent Classes of Adverse and Benevolent Childhood Experiences in a Multinational Sample of Parents and Their Relation to Parent, Child, and Family Functioning during the COVID-19 Pandemic Open
Adverse Childhood Experiences (ACEs) are known to contribute to later mental health. Conversely, Benevolent Childhood Experiences (BCEs) may buffer against mental health difficulties. The importance of ACEs and BCEs for mental health of bo…
View article: Family‐based care buffers the stress sensitizing effect of early deprivation on executive functioning difficulties in adolescence
Family‐based care buffers the stress sensitizing effect of early deprivation on executive functioning difficulties in adolescence Open
We examined whether family care following early‐life deprivation buffered the association between stressful life events (SLEs) and executive functioning (EF) in adolescence. In early childhood, 136 institutionally reared children were rand…
View article: Early deprivation alters structural brain development from middle childhood to adolescence
Early deprivation alters structural brain development from middle childhood to adolescence Open
Hypotheses concerning the biologic embedding of early adversity via developmental neuroplasticity mechanisms have been proposed on the basis of experimental studies in animals. However, no studies have demonstrated a causal link between ea…
View article: Pandemic-Related Disruption and Positive Adaptation: Profiles of Family Function at the Onset of the Pandemic
Pandemic-Related Disruption and Positive Adaptation: Profiles of Family Function at the Onset of the Pandemic Open