Markanday Sharma
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View article: Assessment of quality of life and effect of counseling on psychosocial development of children with congenital anomalies undergoing multiple corrective surgeries: An outpatient-based retrospective cohort study
Assessment of quality of life and effect of counseling on psychosocial development of children with congenital anomalies undergoing multiple corrective surgeries: An outpatient-based retrospective cohort study Open
Objectives: To assess the long-term quality of life of family members of paediatric patients with congenital anomalies undergoing multiple corrective surgeries and to identify the factors associated with better outcomes. Materials and Meth…
View article: Translational research in psychiatry
Translational research in psychiatry Open
Translational research in psychiatry bridges the gap between basic scientific discoveries and clinical applications, aiming to improve the diagnosis, treatment, and prevention of mental illnesses. By elucidating the neurobiological mechani…
View article: Childhood trauma in bipolar affective disorder: A case control study
Childhood trauma in bipolar affective disorder: A case control study Open
Background: The etiology of Bipolar Affective Disorder (BPAD) is influenced by a variety of factors, possibly related to gene-environment interactions. Childhood trauma (CT) has been associated with an increased risk of developing BPAD. It…
View article: Machine minds: Artificial intelligence in psychiatry
Machine minds: Artificial intelligence in psychiatry Open
Diagnostic and interventional aspects of psychiatric care can be augmented by the use of digital health technologies. Recent studies have tried to explore the use of artificial intelligence-driven technologies in screening, diagnosing, and…
View article: Effectiveness of Quetiapine as a Mood Stabilizer: A Case Series
Effectiveness of Quetiapine as a Mood Stabilizer: A Case Series Open
Introduction: Bipolar affective disorder (BD) had a chronic episodic course with recurrent episodes of mania or depression, leading to socio-occupational dysfunction. Standard pharmacology is dependent on conventional mood stabilizers, suc…
View article: Bortezomib Induced Mania: An Unrivalled Case Report
Bortezomib Induced Mania: An Unrivalled Case Report Open
The second most common haematological malignancy, Multiple Myeloma (MM), is caused by the clonal proliferation of malignant plasma cells.With little side effects, Bortezomib, first proteasome inhibitor, increased response rates and overall…
View article: Childhood trauma and bipolar affective disorder: Is there a linkage?
Childhood trauma and bipolar affective disorder: Is there a linkage? Open
Bipolar affective disorder (BPAD) is a major psychiatric illness impairing the quality of life. The etiology of BPAD is influenced by different factors possibly related to gene-environment interactions. Approximately 30% to 50% of individu…
View article: Gut–brain axis
Gut–brain axis Open
Since decades, there is a change in concept of the gut–brain axis. There is differential increase in evidences focusing on the bidirectional communication between the gut microbiome and the brain. It supports existence of far-reaching mode…
View article: First-rank symptoms in Bipolar disorder
First-rank symptoms in Bipolar disorder Open
Despite their description as characteristic symptoms of schizophrenia, first-rank symptoms (FRS) are also seen in other conditions.[1] The prevalence of FRS was 70% in schizophrenia, 29% in psychotic bipolar disorder, and 18% in psychotic …