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View article: Effects of 12-month physical and cognitive training on sarcopenia determinants in older adults: a subgroup analysis of a randomised clinical trial
Effects of 12-month physical and cognitive training on sarcopenia determinants in older adults: a subgroup analysis of a randomised clinical trial Open
View article: Low physical activity is a risk factor for sarcopenia: a cross-sectional analysis of two exercise trials on community-dwelling older adults
Low physical activity is a risk factor for sarcopenia: a cross-sectional analysis of two exercise trials on community-dwelling older adults Open
Background Physical inactivity is an important factor in the development of sarcopenia. This cross-sectional study explores the prevalence of sarcopenia and associations of physical activity (PA) with sarcopenia in two exercise trial popul…
View article: The Impact of Multimorbidity Patterns on Changes in Physical Activity and Physical Capacity Among Older Adults Participating in a Year-Long Exercise Intervention
The Impact of Multimorbidity Patterns on Changes in Physical Activity and Physical Capacity Among Older Adults Participating in a Year-Long Exercise Intervention Open
This study investigated the impact of multimorbidity patterns on physical activity and capacity outcomes over the course of a year-long exercise intervention, and on physical activity 1 year later. Participants were 314 physically inactive…
View article: Changes in femoral neck bone mineral density and structural strength during a 12-month multicomponent exercise intervention among older adults – Does accelerometer-measured physical activity matter?
Changes in femoral neck bone mineral density and structural strength during a 12-month multicomponent exercise intervention among older adults – Does accelerometer-measured physical activity matter? Open
Age-related bone loss is to some extent unavoidable, but it may be decelerated with regular exercise continued into older age. Daily physical activity alongside structured exercise may be an important stimulus for maintaining bone strength…
View article: Effects of Physical and Cognitive Training on Falls and Concern About Falling in Older Adults: Results From a Randomized Controlled Trial
Effects of Physical and Cognitive Training on Falls and Concern About Falling in Older Adults: Results From a Randomized Controlled Trial Open
Background The aim of this study is to investigate whether combined cognitive and physical training provides additional benefits to fall prevention when compared with physical training (PT) alone in older adults. Methods This is a prespeci…
View article: The effects of a physical and cognitive training intervention vs. physical training alone on older adults’ physical activity: A randomized controlled trial with extended follow-up during COVID-19
The effects of a physical and cognitive training intervention vs. physical training alone on older adults’ physical activity: A randomized controlled trial with extended follow-up during COVID-19 Open
Background Executive functions underlie self-regulation and are thus important for physical activity and adaptation to new situations. The aim was to investigate, if yearlong physical and cognitive training (PTCT) had greater effects on ph…
View article: Interactive effects of aging and aerobic capacity on energy metabolism–related metabolites of serum, skeletal muscle, and white adipose tissue
Interactive effects of aging and aerobic capacity on energy metabolism–related metabolites of serum, skeletal muscle, and white adipose tissue Open
Aerobic capacity is a strong predictor of longevity. With aging, aerobic capacity decreases concomitantly with changes in whole body metabolism leading to increased disease risk. To address the role of aerobic capacity, aging, and their in…
View article: Regular Strength and Sprint Training Counteracts Bone Aging: A 10‐Year Follow‐Up in Male Masters Athletes
Regular Strength and Sprint Training Counteracts Bone Aging: A 10‐Year Follow‐Up in Male Masters Athletes Open
Cross‐sectional and interventional studies suggest that high‐intensity strength and impact‐type training provide a powerful osteogenic stimulus even in old age. However, longitudinal evidence on the ability of high‐intensity training to at…
View article: Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease
Central aortic hemodynamics following acute lower and upper-body exercise in a cold environment among patients with coronary artery disease Open
Exercise is beneficial to cardiovascular health, evidenced by reduced post-exercise central aortic blood pressure (BP) and wave reflection. We assessed if post-exercise central hemodynamics are modified due to an altered thermal state rela…
View article: Associations of neuroticism with falls in older adults: do psychological factors mediate the association?
Associations of neuroticism with falls in older adults: do psychological factors mediate the association? Open
The results indicate that concern about falling and depressive symptoms mediate the association between neuroticism and falling. Longitudinal studies are needed to confirm the causality of the findings and to examine the potential to reduc…
View article: Accelerometer-measured and self-reported physical activity in relation to extraversion and neuroticism: a cross-sectional analysis of two studies
Accelerometer-measured and self-reported physical activity in relation to extraversion and neuroticism: a cross-sectional analysis of two studies Open
Background Personality reflects relatively stable and pervasive tendencies in feeling, thinking and behaving. While previous studies have found higher extraversion and lower neuroticism to be linked to higher self-reported physical activit…
View article: Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue
Interactive effects of aging and aerobic capacity on energy metabolism-related metabolites of serum, skeletal muscle, and white adipose tissue Open
Aerobic capacity is a strong predictor of longevity. With aging, aerobic capacity decreases concomitantly with changes in whole body metabolism leading to increased disease risk. To address the role of aerobic capacity, aging and their int…
View article: Associations of physical activity in detailed intensity ranges with body composition and physical function. a cross-sectional study among sedentary older adults
Associations of physical activity in detailed intensity ranges with body composition and physical function. a cross-sectional study among sedentary older adults Open
Background Physical activity is crucial to maintain older adults’ health and functioning, but the health benefits of particular activity intensities remain unclear. The aim of this cross-sectional study was to peruse the distribution of ph…
View article: Does sex hormone-binding globulin cause insulin resistance during pubertal growth?
Does sex hormone-binding globulin cause insulin resistance during pubertal growth? Open
Background The directional influences between serum sex hormone-binding globulin (SHBG), adiposity and insulin resistance during pubertal growth remain unclear. The aim of this study was to investigate bidirectional associations between SH…
View article: Promoting safe walking among older people: the effects of a physical and cognitive training intervention vs. physical training alone on mobility and falls among older community-dwelling men and women (the PASSWORD study): design and methods of a randomized controlled trial
Promoting safe walking among older people: the effects of a physical and cognitive training intervention vs. physical training alone on mobility and falls among older community-dwelling men and women (the PASSWORD study): design and methods of a randomized controlled trial Open
View article: Cardiovascular responses to cold and submaximal exercise in patients with coronary artery disease
Cardiovascular responses to cold and submaximal exercise in patients with coronary artery disease Open
Regular year-round exercise is recommended for patients with coronary artery disease (CAD). However, the combined effects of cold and moderate sustained exercise, both known to increase cardiac workload, on cardiovascular responses are not…
View article: Promoting safe walking among older people: the effects of a physical and cognitive training intervention vs. physical training alone on mobility and falls among older community-dwelling men and women (the PASSWORD study): design and methods of a randomized controlled trial
Promoting safe walking among older people: the effects of a physical and cognitive training intervention vs. physical training alone on mobility and falls among older community-dwelling men and women (the PASSWORD study): design and methods of a randomized controlled trial Open
View article: 0309 HIGHER MORNING FASTING PLASMA NEFA LEVEL IS ASSOCIATED WITH WORSE QUALITY OF SLEEP AMONG OVERWEIGHT MEN WITH CHRONIC INSOMNIA SYMPTOMS
0309 HIGHER MORNING FASTING PLASMA NEFA LEVEL IS ASSOCIATED WITH WORSE QUALITY OF SLEEP AMONG OVERWEIGHT MEN WITH CHRONIC INSOMNIA SYMPTOMS Open
High circulating non-esterified fatty acid (NEFA) level is an independent risk factor of type 2 diabetes and cardiovascular diseases. Recent study showed that sleep restriction elevated morning fasting NEFA among healthy adults, which impl…
View article: Normal‐weight obesity and cardiometabolic risk: A 7‐year longitudinal study in girls from prepuberty to early adulthood
Normal‐weight obesity and cardiometabolic risk: A 7‐year longitudinal study in girls from prepuberty to early adulthood Open
Objective To study whether normal‐weight obesity in childhood is associated with increased cardiometabolic risk in early adulthood. Methods This study assessed data for 236 girls followed from prepuberty to early adulthood. Growth chart da…
View article: Aging and serum exomiR content in women-effects of estrogenic hormone replacement therapy
Aging and serum exomiR content in women-effects of estrogenic hormone replacement therapy Open
View article: Leukocyte and Skeletal Muscle Telomere Length and Body Composition in Monozygotic Twin Pairs Discordant for Long-term Hormone Replacement Therapy
Leukocyte and Skeletal Muscle Telomere Length and Body Composition in Monozygotic Twin Pairs Discordant for Long-term Hormone Replacement Therapy Open
Estrogen-based hormone replacement therapy (HRT) may be associated with deceleration of cellular aging. We investigated whether long-term HRT has effects on leukocyte (LTL) or mean and minimum skeletal muscle telomere length (SMTL) in a de…
View article: Declining Physical Performance Associates with Serum FasL, miR-21, and miR-146a in Aging Sprinters
Declining Physical Performance Associates with Serum FasL, miR-21, and miR-146a in Aging Sprinters Open
Aging is associated with systemic inflammation and cellular apoptosis accelerating physiological dysfunctions. Whether physically active way of life affects these associations is unclear. This study measured the levels of serum inflammator…
View article: Effect of Six-Month Diet Intervention on Sleep among Overweight and Obese Men with Chronic Insomnia Symptoms: A Randomized Controlled Trial
Effect of Six-Month Diet Intervention on Sleep among Overweight and Obese Men with Chronic Insomnia Symptoms: A Randomized Controlled Trial Open
Growing evidence suggests that diet alteration affects sleep, but this has not yet been studied in adults with insomnia symptoms. We aimed to determine the effect of a six-month diet intervention on sleep among overweight and obese (Body m…
View article: Effects of resistance training on expression of IGF‐I splice variants in younger and older men
Effects of resistance training on expression of IGF‐I splice variants in younger and older men Open
Insulin‐like growth factor‐I (IGF‐I) and its splice variants Insulin‐like growth factor‐I isoform Ea (IGF‐IEa) and mechano growth factor (MGF) may play an important role in muscular adaptations to resistance training (RT) that may be modul…
View article: Insulin resistance is associated with altered amino acid metabolism and adipose tissue dysfunction in normoglycemic women
Insulin resistance is associated with altered amino acid metabolism and adipose tissue dysfunction in normoglycemic women Open
Insulin resistance is associated adiposity, but the mechanisms are not fully understood. In this study, we aimed to identify early metabolic alterations associated with insulin resistance in normoglycemic women with varying degree of adipo…
View article: Serum Amino Acid Profiles in Childhood Predict Triglyceride Level in Adulthood: A 7-Year Longitudinal Study in Girls
Serum Amino Acid Profiles in Childhood Predict Triglyceride Level in Adulthood: A 7-Year Longitudinal Study in Girls Open
Context: Branched-chain and aromatic amino acids are associated with high risk of developing dyslipidemia and type II diabetes in adults. Objective: This study aimed to examine whether serum amino acid profiles associate with triglyceride …
View article: Effects of aerobic exercise on home-based sleep among overweight and obese men with chronic insomnia symptoms: a randomized controlled trial
Effects of aerobic exercise on home-based sleep among overweight and obese men with chronic insomnia symptoms: a randomized controlled trial Open
View article: Adipose Tissue Dysfunction and Altered Systemic Amino Acid Metabolism Are Associated with Non-Alcoholic Fatty Liver Disease
Adipose Tissue Dysfunction and Altered Systemic Amino Acid Metabolism Are Associated with Non-Alcoholic Fatty Liver Disease Open
BackgroundFatty liver is a major cause of obesity-related morbidity and mortality. The aim of this study was to identify early metabolic alterations associated with liver fat accumulation in 50- to 55-year-old men (n = 49) and women (n = 5…