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View article: Prenatal vitamin D supplementation mitigates inflammation-related alveolar remodeling in neonatal mice
Prenatal vitamin D supplementation mitigates inflammation-related alveolar remodeling in neonatal mice Open
Vitamin D-enriched diet during gestation resulted in reduced lung inflammation and matrix remodeling in neonatal mice exposed to clinically relevant, postnatal injury. The results underscore the need to monitor the subclinical effects of v…
View article: Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant
Relationship between impaired BMP signalling and clinical risk factors at early-stage vascular injury in the preterm infant Open
Introduction Chronic lung disease, that is, bronchopulmonary dysplasia (BPD) is the most common complication in preterm infants and develops as a consequence of the misguided formation of the gas-exchange area undergoing prenatal and postn…
View article: Attenuated <scp>PDGF</scp> signaling drives alveolar and microvascular defects in neonatal chronic lung disease
Attenuated <span>PDGF</span> signaling drives alveolar and microvascular defects in neonatal chronic lung disease Open
Neonatal chronic lung disease (nCLD) affects a significant number of neonates receiving mechanical ventilation with oxygen-rich gas (MV-O2). Regardless, the primary molecular driver of the disease remains elusive. We discover significant e…
View article: Absence of TNF-α enhances inflammatory response in the newborn lung undergoing mechanical ventilation
Absence of TNF-α enhances inflammatory response in the newborn lung undergoing mechanical ventilation Open
Bronchopulmonary dysplasia (BPD), characterized by impaired alveolarization and vascularization in association with lung inflammation and apoptosis, often occurs after mechanical ventilation with oxygen-rich gas (MV-O 2 ). As heightened ex…