Markus Rotzinger
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View article: Investigation of the Binding of the Macrolide Antibiotic Telithromycin to Human Serum Albumin by NMR Spectroscopy
Investigation of the Binding of the Macrolide Antibiotic Telithromycin to Human Serum Albumin by NMR Spectroscopy Open
The macrolide antibiotic telithromycin was developed to avoid common antibiotic resistances, yet it has been recently withdrawn from the European market due to severe side effects. Both side effects and the effectiveness of a drug can be r…
View article: Front Cover: Identifying Exchangeable Protons in a 1D NMR Spectrum by Spatially Selective Exchange‐Editing (ChemPhysChem 8/2024)
Front Cover: Identifying Exchangeable Protons in a 1D NMR Spectrum by Spatially Selective Exchange‐Editing (ChemPhysChem 8/2024) Open
The Front Cover illustrates the application of a new method for recording exchange-edited 1D 1H-NMR spectra, where signals show reduced intensities when they are in exchange with other labile hydrogens. In the presence of a molar excess of…
View article: Identifying Exchangeable Protons in a 1D NMR Spectrum by Spatially Selective Exchange‐Editing
Identifying Exchangeable Protons in a 1D NMR Spectrum by Spatially Selective Exchange‐Editing Open
The front cover artwork is provided by Markus Rotzinger at the University of Graz, Austria. The front cover picture illustrates the way the 1D exchange‐editing NMR method makes exchanging protons visible by sign alteration. The depicted sp…
View article: Identifying Exchangeable Protons in a 1D NMR Spectrum by Spatially Selective Exchange‐Editing
Identifying Exchangeable Protons in a 1D NMR Spectrum by Spatially Selective Exchange‐Editing Open
Signals undergoing chemical or conformational exchange in one‐dimensional NMR spectra are often identified by deuterium exchange. In order to obtain quantitative information about the dynamic processes involved, one frequently used method …
View article: Vibrio cholerae’s ToxRS bile sensing system
Vibrio cholerae’s ToxRS bile sensing system Open
The seventh pandemic of the diarrheal cholera disease, which began in 1960, is caused by the Gram-negative bacterium Vibrio cholerae . Its environmental persistence provoking recurring sudden outbreaks is enabled by V. cholerae’s rapid ada…
View article: Author response: Vibrio cholerae’s ToxRS bile sensing system
Author response: Vibrio cholerae’s ToxRS bile sensing system Open
Full text Figures and data Side by side Abstract Editor's evaluation eLife digest Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abs…
View article: <i>Vibrio cholerae’s</i> ToxRS Bile Sensing System
<i>Vibrio cholerae’s</i> ToxRS Bile Sensing System Open
Cholera represents a diarrheal disease caused by the Gram-negative bacterium Vibrio cholerae . Its environmental persistence causing recurring sudden outbreaks is enabled by V. cholerae’s rapid adaption to changing environments involving s…