Markus S. Brunner
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View article: Homocysteine leads to aortic stiffening in a rabbit model of atherosclerosis
Homocysteine leads to aortic stiffening in a rabbit model of atherosclerosis Open
Hyperhomocysteinemia, an elevated level of homocysteine in the blood, is an independent risk factor for atherosclerosis and, more generally, cardiovascular disease. However, its relationship with aortic biomechanics has not been investigat…
View article: Homocysteine Leads to Decreased Acylcarnitine Levels in the Heart in a Rabbit Model of Atherosclerosis
Homocysteine Leads to Decreased Acylcarnitine Levels in the Heart in a Rabbit Model of Atherosclerosis Open
Cardiovascular disease, the leading cause of death worldwide, is mainly a result of atherosclerosis. However, 50% of all cases of atherosclerosis still cannot be explained by known risk factors including hypercholesterolemia. Hyperhomocyst…
View article: Accumulation of S-adenosyl-L-homocysteine impairs methylation and development in Saccharomyces cerevisiae and Drosophila melanogaster
Accumulation of S-adenosyl-L-homocysteine impairs methylation and development in Saccharomyces cerevisiae and Drosophila melanogaster Open
S-adenosyl-L-homocysteine (SAH), the product inhibitor of S-adenosyl-L-methionine (SAM)-dependent methyltransferases, and its degradation product homocysteine (Hcy) are evolutionarily conserved master regulators of methylation metabolism. …
View article: Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia
Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia Open
Atherosclerosis, the leading cause of cardiovascular disease, cannot be sufficiently explained by established risk factors, including cholesterol. Elevated plasma homocysteine (Hcy) is an independent risk factor for atherosclerosis and is …
View article: Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia
Homocysteine contributes to atherogenic transformation of the aorta in rabbits in the absence of hypercholesterolemia Open
Atherosclerosis, the leading cause of cardiovascular disease, cannot be sufficiently explained by established risk factors such as cholesterol. Elevated plasma homocysteine (Hcy) is an independent risk factor for atherosclerosis and is clo…