Markus Weiger
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View article: Making <scp>RF</scp> coils <scp>MR</scp> ‐invisible by additive manufacturing using magnetically filled polymer
Making <span>RF</span> coils <span>MR</span> ‐invisible by additive manufacturing using magnetically filled polymer Open
Purpose Short‐T 2 MRI is sensitive not only to targeted tissues but also to signals from materials in RF coils, which can lead to image background artifacts. Current solutions to this problem either compromise imaging performance or impose…
View article: A unipolar head gradient for high‐field <scp>MRI</scp> without encoding ambiguity
A unipolar head gradient for high‐field <span>MRI</span> without encoding ambiguity Open
Purpose MRI gradients with a conventional, bipolar design generally face a trade‐off among performance, encoding ambiguity, and radiofrequency selectivity used to circumvent said ambiguity. This problem is particularly limiting in cutting‐…
View article: Myelin bilayer mapping in the human brain in vivo
Myelin bilayer mapping in the human brain in vivo Open
Purpose To quantitatively map the myelin lipid‐protein bilayer in the live human brain. Methods This goal was pursued by integrating a multi‐TE acquisition approach targeting ultrashort T 2 signals with voxel‐wise fitting to a three‐compon…
View article: Quantitative magnetic resonance mapping of the myelin bilayer reflects pathology in multiple sclerosis brain tissue
Quantitative magnetic resonance mapping of the myelin bilayer reflects pathology in multiple sclerosis brain tissue Open
Multiple sclerosis (MS) is a neuroinflammatory disease characterized by loss of myelin (demyelination) and, to a certain extent, subsequent myelin repair (remyelination). To better understand the pathomechanisms underlying de- and remyelin…
View article: Mapping the myelin bilayer with <scp>short‐T<sub>2</sub> MRI</scp>: Methods validation and reference data for healthy human brain
Mapping the myelin bilayer with <span>short‐T<sub>2</sub> MRI</span>: Methods validation and reference data for healthy human brain Open
Purpose To explore the properties of short‐T 2 signals in human brain, investigate the impact of various experimental procedures on these properties and evaluate the performance of three‐component analysis. Methods Eight samples of non‐pat…
View article: Pulse encoding for ZTE imaging: RF excitation without dead‐time penalty
Pulse encoding for ZTE imaging: RF excitation without dead‐time penalty Open
Purpose To overcome limitations in the duration of RF excitation in zero‐TE (ZTE) MRI by exploiting intrinsic encoding properties of RF pulses to retrieve data missed during the dead time caused by the pulse. Methods An enhanced ZTE signal…
View article: HYFI: Hybrid filling of the dead‐time gap for faster zero echo time imaging
HYFI: Hybrid filling of the dead‐time gap for faster zero echo time imaging Open
The aim of this work was to improve the SNR efficiency of zero echo time (ZTE) MRI pulse sequences for faster imaging of short‐ T 2 components at large dead‐time gaps. ZTE MRI with hybrid filling (HYFI) is a strategy for retrieving inner k…
View article: HYFI: Hybrid filling of the dead-time gap for faster zero echo time imaging
HYFI: Hybrid filling of the dead-time gap for faster zero echo time imaging Open
Purpose To improve the SNR efficiency of zero echo time (ZTE) MRI pulse sequences for faster imaging of short- T 2 components at large dead-time gaps. Methods HYFI is s strategy of retrieving inner k-space data missed during the dead-time …
View article: A virtually 1H‐free birdcage coil for zero echo time MRI without background signal
A virtually 1H‐free birdcage coil for zero echo time MRI without background signal Open
Purpose MRI of tissues with rapid transverse relaxation can be performed efficiently using the zero echo time (ZTE) technique. At high bandwidths leading to large relative initial radiofrequency (RF) dead times, the method becomes increasi…
View article: Separation of collagen‐bound and porous bone‐water longitudinal relaxation in mice using a segmented inversion recovery zero‐echo‐time sequence
Separation of collagen‐bound and porous bone‐water longitudinal relaxation in mice using a segmented inversion recovery zero‐echo‐time sequence Open
Purpose Cortical bone mechanical properties are related to the collagen‐bound water (CBW) and pore water (PW) components of cortical bone. The study evaluates the feasibility of zero‐echo‐time imaging in mice in vivo for longitudinal relax…
View article: Magnetization transfer as a potential tool for the early detection of acute graft rejection after lung transplantation in mice
Magnetization transfer as a potential tool for the early detection of acute graft rejection after lung transplantation in mice Open
Purpose To investigate the value of magnetization transfer (MT) measurements for assessment of acute rejection (AR) in a murine lung transplantation model. Materials and Methods Thirty mice including 15 C57BL/10 mice serving as donors and …
View article: In vivo magnetization transfer imaging of the lung using a zero echo time sequence at 4.7 Tesla in mice: Initial experience
In vivo magnetization transfer imaging of the lung using a zero echo time sequence at 4.7 Tesla in mice: Initial experience Open
Purpose The aim of the present study was to assess the feasibility of magnetization transfer‐prepared zero echo time (ZTE) imaging of the lung in vivo at high field strength [4.7 Tesla) T] in mice. Methods Eighteen C57BL/10 mice underwent …