Markus Windolf
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View article: Prognostic bone fracture healing simulations in an ovine tibia model validated with in vivo sensors
Prognostic bone fracture healing simulations in an ovine tibia model validated with in vivo sensors Open
Bone fracture healing is a complex physiological process influenced by biomechanical and biomolecular factors. Mechanical stability is crucial for successful healing, and disruptions can lead to delayed healing or nonunion. Bone commonly h…
View article: Experimental and virtual testing of bone-implant systems equipped with the AO Fracture Monitor with regard to interfragmentary movement
Experimental and virtual testing of bone-implant systems equipped with the AO Fracture Monitor with regard to interfragmentary movement Open
Introduction: The management of fractured bones is a key domain within orthopedic trauma surgery, with the prevention of delayed healing and non-unions forming a core challenge. This study evaluates the efficacy of the AO Fracture Monitor …
View article: Severity of Complications after Locking Plate Osteosynthesis in Distal Femur Fractures
Severity of Complications after Locking Plate Osteosynthesis in Distal Femur Fractures Open
Background: Locked plating for distal femur fractures is widely recommended and used. We systematically reviewed clinical studies assessing the benefits and harms of fracture fixation with locked plates in AO/OTA Type 32 and 33 femur fract…
View article: On the importance of accurate elasto-plastic material properties in simulating plate osteosynthesis failure
On the importance of accurate elasto-plastic material properties in simulating plate osteosynthesis failure Open
Background: Plate osteosynthesis is a widely used technique for bone fracture fixation; however, complications such as plate bending remain a significant clinical concern. A better understanding of the failure mechanisms behind plate osteo…
View article: Training with a Novel Digitally Enhanced Hands-On Surgical Training (DEHST) Enhances the Performance During Intramedullary Nail Distal Interlocking
Training with a Novel Digitally Enhanced Hands-On Surgical Training (DEHST) Enhances the Performance During Intramedullary Nail Distal Interlocking Open
Background Freehand distal interlocking of intramedullary nails remains a challenging task. This surgical step is the most difficult part performed at the end of the operation and may have a catastrophic influence on patients’ outcome of n…
View article: In Vitro Testing and Clinical Handling of a Novel Implant Positioning Technology for Proximal Humeral Plating
In Vitro Testing and Clinical Handling of a Novel Implant Positioning Technology for Proximal Humeral Plating Open
Background and Objectives: Fractures of the proximal humerus are common, particularly in elderly populations. Anatomical locking plates target stabilization with a multitude of screws spanning into the humeral head. Sound implant placement…
View article: Statistical Morphology and Fragment Mapping of Complex Proximal Humeral Fractures
Statistical Morphology and Fragment Mapping of Complex Proximal Humeral Fractures Open
Background and Objectives: Proximal humerus fractures (PHFs) are common in the elderly, but the treatment results are often poor. A clear understanding of fracture morphology and distribution of cortical bone loss is important for improved…
View article: Continuous Rod Load Monitoring to Assess Spinal Fusion Status–Pilot In Vivo Data in Sheep
Continuous Rod Load Monitoring to Assess Spinal Fusion Status–Pilot In Vivo Data in Sheep Open
Background and Objectives: Spinal fusion is an effective and widely accepted intervention. However, complications such as non-unions and hardware failures are frequently observed. Radiologic imaging and physical examination are still the g…
View article: Continuous Implant Load Monitoring to Assess Bone Healing Status—Evidence from Animal Testing
Continuous Implant Load Monitoring to Assess Bone Healing Status—Evidence from Animal Testing Open
Background and Objectives: Fracture healing is currently assessed through qualitative evaluation of radiographic images, which is highly subjective in nature. Radiographs can only provide snapshots in time, which are limited due to logisti…
View article: Locking Plates With Computationally Enhanced Screw Trajectories Provide Superior Biomechanical Fixation Stability of Complex Proximal Humerus Fractures
Locking Plates With Computationally Enhanced Screw Trajectories Provide Superior Biomechanical Fixation Stability of Complex Proximal Humerus Fractures Open
Joint-preserving surgical treatment of complex unstable proximal humerus fractures remains challenging, with high failure rates even following state-of-the-art locked plating. Enhancement of implants could help improve outcomes. By overcom…
View article: Validity of a Novel Digitally Enhanced Skills Training Station for Freehand Distal Interlocking
Validity of a Novel Digitally Enhanced Skills Training Station for Freehand Distal Interlocking Open
Background and Objectives: Freehand distal interlocking of intramedullary nails is technically demanding and prone to handling issues. It requires precise placement of a screw through the nail under fluoroscopy guidance and can result in a…
View article: Impact of Bone Cement Augmentation on the Fixation Strength of TFNA Blades and Screws
Impact of Bone Cement Augmentation on the Fixation Strength of TFNA Blades and Screws Open
Background and Objectives: Hip fractures constitute the most debilitating complication of osteoporosis with steadily increasing incidences in the aging population. Their intramedullary nailing can be challenging because of poor anchorage i…
View article: Short-Term Bone Healing Response to Mechanical Stimulation—A Case Series Conducted on Sheep
Short-Term Bone Healing Response to Mechanical Stimulation—A Case Series Conducted on Sheep Open
It is well known that mechanical stimulation promotes indirect fracture healing by triggering callus formation. We investigated the short-term response of healing tissue to mechanical stimulation to compare the changes in tissue stiffness …
View article: Growth modulation of angular deformities with a novel constant force implant concept-preclinical results
Growth modulation of angular deformities with a novel constant force implant concept-preclinical results Open
Purpose Varus-valgus deformities in children and adolescents are often corrected by temporary hemi-epiphysiodesis, in which the physis is bridged by an implant to inhibit growth. With standard implant solutions, the acting forces cannot be…
View article: Generic Implant Positioning Technology Based on Hole Projections in X-Ray Images
Generic Implant Positioning Technology Based on Hole Projections in X-Ray Images Open
Implant placement plays a key role in trauma and orthopedics. In this paper, a generic technological concept for implant positioning assistance is outlined. The system utilizes conventional radiographic devices for imaging and tracking and…
View article: Programable Active Fixator System for Systematic In Vivo Investigation of Bone Healing Processes
Programable Active Fixator System for Systematic In Vivo Investigation of Bone Healing Processes Open
This manuscript introduces a programable active bone fixator system that enables systematic investigation of bone healing processes in a sheep animal model. In contrast to previous systems, this solution combines the ability to precisely c…
View article: Cortical parameters predict bone strength at the tibial diaphysis, but are underestimated by HR‐pQCT and μCT compared to histomorphometry
Cortical parameters predict bone strength at the tibial diaphysis, but are underestimated by HR‐pQCT and μCT compared to histomorphometry Open
Cortical bone and its microstructure are crucial for bone strength, especially at the long bone diaphysis. However, it is still not well‐defined how imaging procedures can be used as predictive tools for mechanical bone properties. This st…
View article: Smart implants in fracture care – only buzzword or real opportunity?
Smart implants in fracture care – only buzzword or real opportunity? Open
The assessment of fracture healing is still marked by a subjective and diffuse outcome due to the lack of clinically available quantitative measures. Without reliable information on the progression of healing and uniform criteria for union…
View article: Cement augmentation of calcar screws may provide the greatest reduction in predicted screw cut-out risk for proximal humerus plating based on validated parametric computational modelling
Cement augmentation of calcar screws may provide the greatest reduction in predicted screw cut-out risk for proximal humerus plating based on validated parametric computational modelling Open
Aims Fixation of osteoporotic proximal humerus fractures remains challenging even with state-of-the-art locking plates. Despite the demonstrated biomechanical benefit of screw tip augmentation with bone cement, the clinical findings have r…
View article: In vivo test of a radiography‐based navigation system for control of derotational osteotomies
In vivo test of a radiography‐based navigation system for control of derotational osteotomies Open
Malalignment of the femur is a frequently encountered problem in orthopaedics entailing manifold consequences for the affected patients. Corrective osteotomies, necessary to restore the physiological and anatomical relationships, face grea…
View article: Secondary Perforation Risk in Plate Osteosynthesis of Unstable Proximal Humerus Fractures: A Biomechanical Investigation of the Effect of Screw Length
Secondary Perforation Risk in Plate Osteosynthesis of Unstable Proximal Humerus Fractures: A Biomechanical Investigation of the Effect of Screw Length Open
Secondary perforation of screws into the joint surface is a commonly reported mechanical fixation failure mode in locked plating of proximal humerus fractures (PHF). This study investigated the influence that screws tip to joint distance (…
View article: Importance of locking plate positioning in proximal humeral fractures as predicted by computer simulations
Importance of locking plate positioning in proximal humeral fractures as predicted by computer simulations Open
Multifragmented proximal humeral fractures frequently require operative fixation. The locking plates commonly used are often placed relative to the greater tuberosity, however no quantitative data exists regarding the effect of positional …
View article: X-Ray based navigation system for torsional correction - first clinical data
X-Ray based navigation system for torsional correction - first clinical data Open
It is well known that treatment of femoral shaft fractures can lead into torsional malalignment. In up to 15% of these cases a torsional correction is necessary. Further there are congenital torsional abnormities causing disbalances in the…