Marta Ciwinska
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View article: Mechanisms that clear mutations drive field cancerization in mammary tissue
Mechanisms that clear mutations drive field cancerization in mammary tissue Open
View article: Ductal carcinoma <i>in situ</i> develops within clonal fields of mutant cells in morphologically normal ducts
Ductal carcinoma <i>in situ</i> develops within clonal fields of mutant cells in morphologically normal ducts Open
Mutations are abundantly present in tissues of healthy individuals, including the breast epithelium. Yet it remains unknown whether mutant cells directly induce lesion formation or first spread, leading to a field of mutant cells that is p…
View article: A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression
A living biobank of patient-derived ductal carcinoma in situ mouse-intraductal xenografts identifies risk factors for invasive progression Open
View article: Longitudinal Intravital Microscopy Using a Mammary Imaging Window with Replaceable Lid
Longitudinal Intravital Microscopy Using a Mammary Imaging Window with Replaceable Lid Open
The branched structure of the mammary gland is highly dynamic and undergoes several phases of growth and remodeling after birth. Intravital microscopy in combination with skin flap surgery or implantation of imaging windows has been used t…