M. SANCHEZ
YOU?
Author Swipe
View article: Quantifying potential carbon dioxide removal via enhanced weathering using porewater from a field trial in Scotland
Quantifying potential carbon dioxide removal via enhanced weathering using porewater from a field trial in Scotland Open
Enhanced weathering (EW) is cited as a promising carbon dioxide removal (CDR) strategy, and is being rapidly commercialized. Rigorous monitoring, reporting and verification (MRV) are essential to ensure carbon claims are accurate and carbo…
View article: Quantifying potential carbon dioxide removal via enhanced weathering using porewater from a field trial in Scotland
Quantifying potential carbon dioxide removal via enhanced weathering using porewater from a field trial in Scotland Open
Enhanced weathering (EW) is cited as a promising carbon dioxide removal (CDR) strategy, and is being rapidly commercialized. Rigorous monitoring, reporting and verification (MRV) are essential to ensure carbon claims are accurate and carbo…
View article: Binding and sensing diverse small molecules using shape-complementary pseudocycles
Binding and sensing diverse small molecules using shape-complementary pseudocycles Open
We describe an approach for designing high-affinity small molecule–binding proteins poised for downstream sensing. We use deep learning–generated pseudocycles with repeating structural units surrounding central binding pockets with widely …
View article: Atomically accurate de novo design of antibodies with RFdiffusion
Atomically accurate de novo design of antibodies with RFdiffusion Open
Despite the central role that antibodies play in modern medicine, there is currently no method to design novel antibodies that bind a specific epitope entirely in silico . Instead, antibody discovery currently relies on animal immunization…
View article: De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles
De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles Open
A general method for designing proteins to bind and sense any small molecule of interest would be widely useful. Due to the small number of atoms to interact with, binding to small molecules with high affinity requires highly shape complem…