Marta Lloret-Llinares
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View article: Correction: An international consensus on effective, inclusive, and career-spanning short-format training in the life sciences and beyond
Correction: An international consensus on effective, inclusive, and career-spanning short-format training in the life sciences and beyond Open
[This corrects the article DOI: 10.1371/journal.pone.0293879.].
View article: Competencies for bioinformatics core facility scientists: extension of the ISCB competency framework for bioinformatics
Competencies for bioinformatics core facility scientists: extension of the ISCB competency framework for bioinformatics Open
Motivation The competency framework of the International Society of Computational Biology (ISCB) provides a benchmark for capturing the knowledge, skills, and attitudes required by bioinformatics professionals. Whilst it provides a minimum…
View article: Opportunities and considerations for using artificial intelligence in bioinformatics education
Opportunities and considerations for using artificial intelligence in bioinformatics education Open
Artificial intelligence (AI) tools and techniques are undoubtedly being used in bioinformatics education, reflecting broader trends in education. However, many instructors and learners may be unaware of the full scope of potential uses for…
View article: The ISCB competency framework v. 3: a revised and extended standard for bioinformatics education and training
The ISCB competency framework v. 3: a revised and extended standard for bioinformatics education and training Open
Motivation Developing competency in the broad area of bioinformatics is challenging globally, owing to the breadth of the field and the diversity of its audiences for education and training. Course design can be facilitated by the use of a…
View article: An international consensus on effective, inclusive, and career-spanning short-format training in the life sciences and beyond
An international consensus on effective, inclusive, and career-spanning short-format training in the life sciences and beyond Open
Science, technology, engineering, mathematics, and medicine (STEMM) fields change rapidly and are increasingly interdisciplinary. Commonly, STEMM practitioners use short-format training (SFT) such as workshops and short courses for upskill…
View article: Optimizing Short-format Training: an International Consensus on Effective, Inclusive, and Career-spanning Professional Development in the Life Sciences and Beyond
Optimizing Short-format Training: an International Consensus on Effective, Inclusive, and Career-spanning Professional Development in the Life Sciences and Beyond Open
Science, technology, engineering, mathematics, and medicine (STEMM) fields change rapidly and are increasingly interdisciplinary. Commonly, STEMM practitioners use short-format training (SFT) such as workshops and short courses for upskill…
View article: Guidelines for developing and updating short courses and course programs using the ISCB competency framework
Guidelines for developing and updating short courses and course programs using the ISCB competency framework Open
Competency frameworks have proved to be a powerful tool for curriculum development and assessment across many subject domains, and the field of computational biology is no exception. Efforts from the ISCB to develop and successivel…
View article: circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation
circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation Open
Circular RNAs are important for many cellular processes but their mechanisms of action remain poorly understood. Here, we map circRNA inventories of mouse embryonic stem cells, neuronal progenitor cells and differentiated neurons and ident…
View article: Author response: circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation
Author response: circZNF827 nucleates a transcription inhibitory complex to balance neuronal differentiation Open
View article: The RNA exosome shapes the expression of key protein-coding genes
The RNA exosome shapes the expression of key protein-coding genes Open
The ribonucleolytic exosome complex is central for nuclear RNA degradation, primarily targeting non-coding RNAs. Still, the nuclear exosome could have protein-coding (pc) gene-specific regulatory activities. By depleting an exosome core co…
View article: BioExcel remote training programme: making training more accessible
BioExcel remote training programme: making training more accessible Open
View article: A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2 Open
View article: The multitasking polyA tail: nuclear RNA maturation, degradation and export
The multitasking polyA tail: nuclear RNA maturation, degradation and export Open
A polyA (pA) tail is an essential modification added to the 3′ ends of a wide range of RNAs at different stages of their metabolism. Here, we describe the main sources of polyadenylation and outline their underlying biochemical interaction…
View article: The RNA exosome contributes to gene expression regulation during stem cell differentiation
The RNA exosome contributes to gene expression regulation during stem cell differentiation Open
Gene expression programs change during cellular transitions. It is well established that a network of transcription factors and chromatin modifiers regulate RNA levels during embryonic stem cell (ESC) differentiation, but the full impact o…
View article: Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities
Transcription start site analysis reveals widespread divergent transcription in D. melanogaster and core promoter-encoded enhancer activities Open
Mammalian gene promoters and enhancers share many properties. They are composed of a unified promoter architecture of divergent transcripton initiation and gene promoters may exhibit enhancer function. However, it is currently unclear how …
View article: Transcription start site analysis reveals widespread divergent transcription in <i>D. melanogaster</i> and core promoter-encoded enhancer activities
Transcription start site analysis reveals widespread divergent transcription in <i>D. melanogaster</i> and core promoter-encoded enhancer activities Open
Mammalian gene promoters and enhancers share many properties. They are composed of a unified promoter architecture of divergent transcripton initiation and gene promoters may exhibit enhancer function. However, it is currently unclear how …
View article: Relationships between PROMPT and gene expression
Relationships between PROMPT and gene expression Open
Most mammalian protein-coding gene promoters are divergent, yielding promoter upstream transcripts (PROMPTs) in the reverse direction from their conventionally produced mRNAs. PROMPTs are rapidly degraded by the RNA exosome rendering a gen…