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Implementation of Uniportal Video-Assisted Thoracoscopic Surgery to Treat Pericardial Effusion: A Review Open
Pericardial effusion is the pathological accumulation of fluid in the pericardial cavity and can lead to life-threatening complications such as cardiac tamponade. While pericardiocentesis and surgical pericardial window creation remain the…
Last-minute cancellation of elective lung cancer surgery is associated with poorer survival Open
OBJECTIVES Our objective was to assess the incidence and reason of last-minute cancellations before surgery for lung cancer and their association with outcomes. METHODS Retrospective analysis on all consecutive patients booked for elective…
P171 Rescuing Intestinal Stem Cells via TMEM219 inhibition promotes mucosal healing in Crohn’s disease Open
Background Intestinal mucosa regeneration is disrupted in inflammatory bowel disease as Chron’s disease, but whether this relies on a defect in intestinal stem cells remains to be established. Methods Transcriptome and receptome profile in…
View article: ERS International Congress 2022: highlights from the Thoracic Surgery and Lung Transplantation Assembly
ERS International Congress 2022: highlights from the Thoracic Surgery and Lung Transplantation Assembly Open
The thoracic surgery and lung transplantation assembly (Assembly 8) of the European Respiratory Society (ERS) is delighted to present the highlights from the 2022 ERS International Congress that took place in a hybrid version in Barcelona,…
Editorial: Integration of structural biology data in lead drug discovery and optimization Open
EDITORIAL article Front. Mol. Biosci., 01 February 2023Sec. Structural Biology Volume 10 - 2023 | https://doi.org/10.3389/fmolb.2023.1145834
Salvage debulking surgery and hyperthermic intrathoracic chemotherapy for massive recurrent mesothelioma in the mediastinum Open
Mediastinal malignant pleural mesothelioma with signs of tamponade is rare. Indication for reoperation for recurrent malignant pleural mesothelioma is a controversial but viable option in selected patients. We report a case of a 68-year-ol…
Comparison of VATS Pleurectomy/Decortication Surgery plus Hyperthermic Intrathoracic Chemotherapy with VATS talc pleurodesis for the treatment of Malignant Pleural Mesothelioma: a randomized pilot study Open
Introduction No previous study provides compelling evidence to convince surgeons to opt for one procedure over another for the treatment of Malignant Pleural Mesothelioma (MPM). Hyperthermic intrathoracic chemotherapy (HITHOC) adjunct to s…
S73 Management of bronchial stenosis in post lung transplantation – initial evaluation of biodegradable stents Open
Introduction Bronchial stenosis one of the most common airway complications post lung transplantation. The incidence varies from about 5 to 20, most commonly seen between 2 to 9 months post transplantation and is a significant cause of mor…
ARCHITETTURA MOLECOLARE DI FATTORI DI TRASCRIZIONE DEL DNA Open
Transcription factors are proteins involved in one of the most important molecular processes in living cells: the expression of genes through a mechanism called “transcription”. Transcription factors, their structure, and function are the …
The outcome of patients treated with salvage surgery after chemo-radiotherapy for locally advanced non-small cell lung carcinoma Open
Local relapse or persistent disease after definitive chemo radiotherapy for locally advanced non-small cell lung cancer (NSCLC) occurs in 24% to 35% of patients. Patients treated with chemo-radiotherapy or surgery alone have a poor prognos…
Imaging patterns of early stage lung cancer for the thoracic surgeon Open
In the modern era, thoracic surgeons are experiencing an increase interest in imaging patterns of early stage lung cancer due to the introduction of the ground glass opacity in clinical practice, and for the necessity to an accurate cancer…
Does cytoreduction surgery and hyperthermic intrathoracic chemotherapy prolong survival in patients with N0–N1 nonsmall cell lung cancer and malignant pleural effusion? Open
Introduction Debulking surgery and hyperthermic intrathoracic chemotherapy (HITHOC) has been successfully used in the treatment of thoracic tumours. Few authors report on the feasibility of its use in patients with lung cancer and malignan…
The future of thoracic surgery: articulated instruments Open
Thoracic surgery is living an enthusiastic era of thriving innovations. The changes in the fields of diagnostics, in the therapeutic options, the development of surgical techniques and the adoption of novel technologies has radically chang…
Higher Number of Night Shifts Associates with Good Perception of Work Capacity and Optimal Lung Function but Correlates with Increased Oxidative Damage and Telomere Attrition Open
Sleep deprivation and the consequent circadian clock disruption has become an emergent health question being associated with premature aging and earlier chronic diseases onset. Night-shift work leads to circadian clock misalignment, which …
Subxiphoid robotic-assisted right pneumonectomy Open
A 70-year-old lady, an ex-smoker, was referred with a 3-month history of a non-productive cough. Her past medical history included hypertension, type II diabetes mellitus and marginal zone lymphoma of the skin in 2015. The computed tomogra…
Medical student exposure to cardiothoracic surgery in the United Kingdom Open
OBJECTIVES There has been declining interest in cardiothoracic surgery amongst medical graduates. This survey examines the exposure of British medical students to cardiothoracic surgery in various settings and its relationship with student…
The Reamer-Irrigator-Aspirator technique for manubriosternal non-union repair Open
Autologous bone graft is used in the treatment of fracture non-unions. A novel approach to treat painful manubriosternal non-unions is described with bone graft harvested from the femur and plating.
Predicting return to work after acute myocardial infarction: Socio-occupational factors overcome clinical conditions Open
These findings suggest that the strongest predictors of returning to work within 1 year after discharge for an acute myocardial infarction are related more to socio-occupational than to clinical parameters.
Extended pleurectomy decortication: the current role Open
Extended pleurectomy/decortication (EPD) has been formally defined but there remain technical areas of debate between practitioners. This is partly attributable to the relative rarity of this operation which is largely confined to a small …
Forced expiratory volume in one second: A novel predictor of work disability in subjects with suspected obstructive sleep apnea Open
Whether the association of work disability with obstructive sleep apnea (OSA) is mainly due to the disease, i.e. the number and frequency of apneas-hypoapneas, or to coexisting factors independent from the disease, is not well-established.…
A pragmatic view of the usefulness of video-mediastinoscopy in the modern era Open
As a result of the introduction of new technologies, such as endoscopic (EUS) and endobronchial ultrasound (EBUS) guided aspiration, surgeons are moving away from routine mediastinoscopy prior to lung cancer resection. The scope of this ar…
Microlobectomy: completely portal pulmonary lobectomy Open
Background: Video assisted pulmonary lobectomy is 25 years old. Despite the recent advancement of minimally invasive surgery, this procedure is still related to a considerable amount of post-operative pain. We describe the results with ‘Mi…
Right VATS thymectomy, utilising a subxiphoid incision and the LigaSure retractable L-hook Open
We describe a technique of right sided video-assisted thoracoscopic surgery (VATS) thymectomy in a lady who had a large 7 cm mass which was adherent to the pericardium, extended into the superior poles of the thymus and had adhesions to th…
Robotic resection of a middle mediastinal mass Open
Aorto-pulmonary paraganglioma is an exceptionally rare condition, and its diagnosis and treatment are a challenge for the general thoracic surgeon. We describe the case of a 35 years old man who was incidentally diagnosed with a visceral m…
Robotic left lower sleeve lobectomy with bronchoplasty for the removal of a carcinoid tumour Open
Lung carcinoid tumours constitute approximately 1-2% of all pulmonary tumours. They are derived from enterochromaffin cells, which are also known as 'Kulchitsky cells' and generally have indolent growth and development patterns. Carcinoid …
Ground glass opacities management in the lung cancer screening era Open
Pulmonary ground glass opacity (GGO) is becoming an important clinical dilemma in oncology as its diagnosis in clinical practice is increasing due to the introduction of low dose computed tomography (CT) scan and screening. The incidence o…
99mTechnetium and methylene blue guided pulmonary nodules resections: preliminary British experience Open
We conclude that technetium guided pulmonary nodule resection is a very reliable method for localization and resection of subcentimetre nodules which may be otherwise be difficult to identify.