Marta Stracuzzi
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View article: Short‐lived neutralizing activity against SARS‐CoV‐2 in newborns of immunized mothers
Short‐lived neutralizing activity against SARS‐CoV‐2 in newborns of immunized mothers Open
Background Newborns under 6 months of age are at high risk of hospitalization for acute respiratory failure following SARS‐CoV‐2 infection. Herein, we analyzed neonatal protection against SARS‐CoV‐2 passively acquired after mother vaccinat…
View article: Missed vaccines in pregnant women: A contributing factor to pertussis outbreak in newborns and infants
Missed vaccines in pregnant women: A contributing factor to pertussis outbreak in newborns and infants Open
View article: Effectiveness and Safety of Glecaprevir/Pibrentasvir in Italian Children and Adolescents With Chronic Hepatitis C: A Real‐Word, Multicenter Study
Effectiveness and Safety of Glecaprevir/Pibrentasvir in Italian Children and Adolescents With Chronic Hepatitis C: A Real‐Word, Multicenter Study Open
Background & Aims Glecaprevir/Pibrentasvir (GLE/PIB) has been approved by the European Medicine Agency (EMA) and by the US Food and Drug Administration (US‐FDA) for the treatment of children and adolescents from 3 years of age with chronic…
View article: Bacterial-like inflammatory response in children with adenovirus leads to inappropriate antibiotic use: a multicenter cohort study
Bacterial-like inflammatory response in children with adenovirus leads to inappropriate antibiotic use: a multicenter cohort study Open
View article: Natural History and Management of Hepatitis C in Children: 25 Years Experience of a Reference Center in Northern Italy
Natural History and Management of Hepatitis C in Children: 25 Years Experience of a Reference Center in Northern Italy Open
Hepatitis C virus (HCV) infection natural history and management in the pediatric population are still debated. We retrospectively evaluated the outcome of a HCV pediatric population managed at the Pediatric Infectious Disease Unit of Luig…
View article: Humoral and cell-mediated immune responses in HIV-vertically infected young patients after three doses of the BNT162b2 mRNA SARS-CoV-2 vaccine
Humoral and cell-mediated immune responses in HIV-vertically infected young patients after three doses of the BNT162b2 mRNA SARS-CoV-2 vaccine Open
Background Data on the efficacy of three SARS-CoV-2 mRNA BNT162b2 vaccine doses and the role of previous SARS-CoV-2-infection in enhancing vaccine immunogenicity in HIV-vertically-infected people living with HIV (PLWH) are limited, as is t…
View article: Immunophenotypes of Newborns From SARS-CoV-2-infected Mothers
Immunophenotypes of Newborns From SARS-CoV-2-infected Mothers Open
Background: Little is known about the neonatal immunologic response to a maternal SARS-CoV-2 infection present during childbirth. Here we analyze a cohort of 75 neonates from SARS-CoV-2-infected mothers. Methods: The SARS-CoV-2 infection s…
View article: The Immunological Profile of SARS-CoV-2 Infection in Children Is Linked to Clinical Severity and Age
The Immunological Profile of SARS-CoV-2 Infection in Children Is Linked to Clinical Severity and Age Open
Coronavirus disease 19 (COVID-19) is clinically less severe in children, even if the wide variety and degree of severity of symptoms reported in children pose a still-unresolved challenge for clinicians. We performed an in-depth analysis o…
View article: <scp>SARS‐CoV</scp> ‐2 infection in a X‐linked agammaglobulinemia adolescent: An immunological approach to treatment
<span>SARS‐CoV</span> ‐2 infection in a X‐linked agammaglobulinemia adolescent: An immunological approach to treatment Open
View article: The immunological profile of SARS-CoV-2 infection in children is linked to clinical severity and age
The immunological profile of SARS-CoV-2 infection in children is linked to clinical severity and age Open
Coronavirus disease 19 (COVID-19) is clinically less severe in children, even if the large variety and degree of severity of symptoms reported in children pose a still unresolved challenge to clinicians. We performed an in-depth analysis o…
View article: Adherence of systematic reviews to Cochrane RoB2 guidance was frequently poor: a meta epidemiological study
Adherence of systematic reviews to Cochrane RoB2 guidance was frequently poor: a meta epidemiological study Open
Many SRs did not adhere to RoB2 guidance as they applied the tool at the study level rather than at the outcome measure level. Lack of adherence was more likely among low and very low quality reviews.
View article: Congenital CMV, Lights and Shadows on Its Management: The Experience of a Reference Center in Northern Italy
Congenital CMV, Lights and Shadows on Its Management: The Experience of a Reference Center in Northern Italy Open
Congenital cytomegalovirus infection (cCMV) is the most common congenital viral infection, with a consistent rate of morbidity, mortality, and long-term sequelae, especially in the case of late diagnosis. Nevertheless, a universal screenin…
View article: Immunological Characterization of HIV and SARS-CoV-2 Coinfected Young Individuals
Immunological Characterization of HIV and SARS-CoV-2 Coinfected Young Individuals Open
While the risk of SARS-CoV-2 infection and/or COVID-19 disease progression in the general population has been largely assessed, its impact on HIV-positive individuals remains unclear. We present clinical and immunological data collected in…
View article: A Systematic Review of Gastrointestinal Manifestations in Children Presenting with COVID-19
A Systematic Review of Gastrointestinal Manifestations in Children Presenting with COVID-19 Open
SARS-CoV-2 infection commonly presents with mild to severe respiratory symptoms and possibly other organs involvement. Gastrointestinal manifestations have been frequently documented in adult patients whilst their occurrence in children is…
View article: Epidemiological, clinical and immunological profile in SARS-CoV-2 co-infected HIV-positive young individuals
Epidemiological, clinical and immunological profile in SARS-CoV-2 co-infected HIV-positive young individuals Open
View article: Defining the clinical phenotype of COVID‐19 in children
Defining the clinical phenotype of COVID‐19 in children Open
On January 7, 2020, a novel coronavirus (SARS‐CoV‐2) was identified as the causative agent of a cluster of pneumonia of unknown origin detected in Wuhan City by Chinese authorities. Since SARS‐CoV‐2 discovery, the corresponding disease (CO…
View article: Gastrointestinal Symptoms in Severe COVID-19 Children
Gastrointestinal Symptoms in Severe COVID-19 Children Open
There are growing evidence of clinical manifestations other than acute respiratory syndrome in severe acute respiratory syndrome associated with coronavirus 2-infected children. In our multicenter retrospective analysis, we observed among …
View article: Vitamin D Supplementation Modulates ICOS+ and ICOS− Regulatory T Cell in Siblings of Children With Type 1 Diabetes
Vitamin D Supplementation Modulates ICOS+ and ICOS− Regulatory T Cell in Siblings of Children With Type 1 Diabetes Open
Objectives Vitamin D plays an immunoregulatory activity. The aim of this study was to assess the correlation between blood serum 25(OH)D levels and Th17 and Treg circulating subsets, mainly Treg/inducible costimulatory-positive (ICOS+), wh…
View article: Acute Inflammation and Elevated Cardiac Markers in a Two-Month-Old Infant with Severe Acute Respiratory Syndrome Coronavirus 2 Infection Presenting with Cardiac Symptoms
Acute Inflammation and Elevated Cardiac Markers in a Two-Month-Old Infant with Severe Acute Respiratory Syndrome Coronavirus 2 Infection Presenting with Cardiac Symptoms Open
Severe acute respiratory syndrome coronavirus 2 infection in children mainly shows a milder course. In complicated cases, it is unknown whether inflammation is predictive of disease severity, as in adults. Moreover, cardiac involvement is …
View article: Favorable effects of omega-3 PUFAs on glucose control in an adolescent with type 1 diabetes using continuous glucose monitoring : a case report
Favorable effects of omega-3 PUFAs on glucose control in an adolescent with type 1 diabetes using continuous glucose monitoring : a case report Open
Omega-3 polyunsaturated fatty acids (PUFAs) represent valuable dietary adjuncts for subjects with hypertriglyceridemia and at increased risk of cardiovascular disease, including subjects with type 1 diabetes (T1D). However, the exact role …
View article: Vitamin D and ω-3 Supplementations in Mediterranean Diet During the 1st Year of Overt Type 1 Diabetes: A Cohort Study
Vitamin D and ω-3 Supplementations in Mediterranean Diet During the 1st Year of Overt Type 1 Diabetes: A Cohort Study Open
Vitamin D and omega 3 fatty acid (ω-3) co-supplementation potentially improves type 1 diabetes (T1D) by attenuating autoimmunity and counteracting inflammation. This cohort study, preliminary to a randomized control trial (RCT), is aimed a…
View article: Vitamin D and &omega;-3 Supplementations in Mediterranean Diet During the 1st Year of Overt Type 1 Diabetes: A Cohort Study
Vitamin D and ω-3 Supplementations in Mediterranean Diet During the 1st Year of Overt Type 1 Diabetes: A Cohort Study Open
Vitamin D and ω-3 fatty acids (ω-3) co-supplementation potentially improve type 1 diabetes (T1D) by attenuating autoimmunity and counteracting inflammation.This cohort study preliminary to a randomized control trial (RCT) is ai…