Martin A. Walter
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View article: Waking up calmer with hypnosis: Jena Safety Anchor reduces cortisol awakening response and morning heart rate in daily life
Waking up calmer with hypnosis: Jena Safety Anchor reduces cortisol awakening response and morning heart rate in daily life Open
With stress being causally linked to the most frequently occurring mental and physical health problems, effective coping with acute stress is essential for promoting overall well-being and building long-term stress resilience. However, mos…
View article: Emotion-focused vs. cognitive interventions of schema therapy for borderline personality disorder: effects on neural emotion regulation networks - study protocol
Emotion-focused vs. cognitive interventions of schema therapy for borderline personality disorder: effects on neural emotion regulation networks - study protocol Open
View article: Relationship between body mass index, gray matter volume and peripheral inflammation in patients with post-COVID condition
Relationship between body mass index, gray matter volume and peripheral inflammation in patients with post-COVID condition Open
The results suggest that BMI contributes to GMV alterations in PCC patients, with both BMI and GMV demonstrating correlations with peripheral immunological markers. These findings indicate that converging mechanisms involving inflammation …
View article: Association between S-ketamine induced changes in glutamate levels in the pregenual anterior cingulate cortex and plasma brain-derived neurotrophic factor in healthy subjects
Association between S-ketamine induced changes in glutamate levels in the pregenual anterior cingulate cortex and plasma brain-derived neurotrophic factor in healthy subjects Open
Introduction Ketamine’s antidepressant effects have been linked to its modulation of glutamatergic neurotransmission and synaptic plasticity. However, the precise roles of both glutamate (Glu) levels and brain-derived neurotrophic factor (…
View article: DRIPS: Domain Randomisation for Image-based Perivascular spaces Segmentation
DRIPS: Domain Randomisation for Image-based Perivascular spaces Segmentation Open
Perivascular spaces (PVS) are emerging as sensitive imaging markers of brain health. Yet, accurate out-of-sample PVS segmentation remains challenging since existing methods are modality-specific, require dataset-specific tuning, or rely on…
View article: Everyday stress-induced neurobehavioral dysregulation: therapeutic targets for management with Neurexan
Everyday stress-induced neurobehavioral dysregulation: therapeutic targets for management with Neurexan Open
Everyday stress is highly prevalent and can impact human health, performance, well-being, and mortality risk. Despite being widely acknowledged, everyday stress is rarely assessed or treated, highlighting a critical gap in clinical routine…
View article: Comprehensive Mitigation of Peripheral and Central Stress Responses by Nx4: Insights From EEG and Heart Rate Variability in Post‐Stress Resting State
Comprehensive Mitigation of Peripheral and Central Stress Responses by Nx4: Insights From EEG and Heart Rate Variability in Post‐Stress Resting State Open
Objective Stress from daily psychosocial challenges is a significant health concern with limited pharmacological treatment options. Psychosocial stress triggers distinct responses in the autonomic and central nervous systems, measurable vi…
View article: The concept, intention, and evaluation of the term treatment-refractory meningioma
The concept, intention, and evaluation of the term treatment-refractory meningioma Open
Background Treatment-refractory meningioma is a widely used term but lacks standardized criteria, impairing research comparability and treatment evaluation. The aim of this study was to assess the heterogeneity of patient populations label…
View article: Connecting the dots: approaching a standardized nomenclature for molecular connectivity in positron emission tomography
Connecting the dots: approaching a standardized nomenclature for molecular connectivity in positron emission tomography Open
Positron emission tomography (PET)-based connectivity analysis provides a molecular perspective that complements fMRI-derived functional connectivity. However, lack of standardized terminology and diverse methodologies in PET connectivity …
View article: Does trait impulsivity differentiate impulsive from non-impulsive suicide attempts?
Does trait impulsivity differentiate impulsive from non-impulsive suicide attempts? Open
View article: Impact of multikinase inhibitors in reshaping the treatment of advanced gastroenteropancreatic neuroendocrine tumors
Impact of multikinase inhibitors in reshaping the treatment of advanced gastroenteropancreatic neuroendocrine tumors Open
Neuroendocrine tumors (NETs) pose a considerable challenge due to their increasing incidence and frequently late-stage diagnosis. The arrival of multikinase inhibitors (MKIs) into clinical practice has brought notable progress in the manag…
View article: Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial)
Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single-center open-label clinical phase I trial (NEON trial) Open
Background Parkinson disease (PD) is a chronic progressive neurodegenerative disorder leading to motor and non-motor impairment, often resulting in severe loss of quality of life. There are symptomatic treatments without effect on the prog…
View article: Quality of data from cancer registries in Italy: An appraisal
Quality of data from cancer registries in Italy: An appraisal Open
We report the results of the quality assessment on data collected by cancer registries belonging to the Italian network of Cancer Registries (AIRTUM). For all malignant cancers diagnosed in 2013-2017, overall percentages of cases known fro…
View article: Perivascular spaces in neuropsychiatric post-COVID syndrome
Perivascular spaces in neuropsychiatric post-COVID syndrome Open
Neuropsychiatric symptoms, such as executive dysfunction, fatigue, and depression, are common and disabling in post-COVID syndrome, often hindering daily activities and work. While the exact mechanisms remain unclear, recent studies sugges…
View article: Altered corticostriatal connectivity in long-COVID patients is associated with cognitive impairment
Altered corticostriatal connectivity in long-COVID patients is associated with cognitive impairment Open
Background The COVID-19 pandemic has had a significant impact on the health of millions of people worldwide, and many manifest new or persistent symptoms long after the initial onset of the infection. One of the leading symptoms of long-CO…
View article: The Theranostic Genome
The Theranostic Genome Open
Theranostic drugs represent an emerging path to deliver on the promise of precision medicine. However, bottlenecks remain in characterizing theranostic targets, identifying theranostic lead compounds, and tailoring theranostic drugs. To ov…
View article: Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome
Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations and immunometabolic interactions in post-COVID condition and myalgic encephalomyelitis/chronic fatigue syndrome Open
Background A considerable number of patients who contracted SARS-CoV-2 are affected by persistent multi-systemic symptoms, referred to as Post-COVID Condition (PCC). Post-exertional malaise (PEM) has been recognized as one of the most freq…
View article: Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single center open-label clinical phase I trial (NEON trial)
Safety and tolerability of intravenous liposomal GM1 in patients with Parkinson disease: A single center open-label clinical phase I trial (NEON trial) Open
Background: Parkinson disease (PD) is a chronic progressive neurodegenerative disorder leading to motor and non- motor impairment often resulting in severe loss of quality of life. There are symptomatic treatments without effect on the pro…
View article: Objective structured clinical examination to teach competency in planetary health care and management – a prospective observational study
Objective structured clinical examination to teach competency in planetary health care and management – a prospective observational study Open
View article: Das Deutsche Zentrum für Psychische Gesundheit
Das Deutsche Zentrum für Psychische Gesundheit Open
View article: Psychological distress among individuals with a suicide attempt or suicidal ideation and suicide attempts patterns: first two years of the pandemic
Psychological distress among individuals with a suicide attempt or suicidal ideation and suicide attempts patterns: first two years of the pandemic Open
Background The COVID-19 pandemic and related restrictions may have led to increased stress, particularly in people with mental health problems. Since stress factors play important role in the emergence of suicide attempts (SA) and suicidal…
View article: Investigating the role of CCL11 in shaping microglial age-and long-Covid-related inflammatory activation
Investigating the role of CCL11 in shaping microglial age-and long-Covid-related inflammatory activation Open
View article: Cortical thickness alterations and systemic inflammation define long-Covid patients with cognitive impairment
Cortical thickness alterations and systemic inflammation define long-Covid patients with cognitive impairment Open
View article: The Imageable Genome
The Imageable Genome Open
View article: Understanding the needs of women undergoing breast ultrasound: Are male radiologists still needed?
Understanding the needs of women undergoing breast ultrasound: Are male radiologists still needed? Open
Introduction A trend towards less male radiologists specializing in breast ultrasound was observed. A common notion in the field of breast radiology is, that female patients feel more comfortable being treated by female radiologists. The a…
View article: Longterm course of neuropsychological symptoms and ME/CFS after SARS-CoV-2-infection: a prospective registry study
Longterm course of neuropsychological symptoms and ME/CFS after SARS-CoV-2-infection: a prospective registry study Open
View article: Variations and Predictors of Post-COVID Syndrome Severity in Patients Attending a Post-COVID Outpatient Clinic
Variations and Predictors of Post-COVID Syndrome Severity in Patients Attending a Post-COVID Outpatient Clinic Open
A relevant proportion of patients suffer from long-lasting impairments following an acute SARS-CoV-2 infection. The proposed post-COVID syndrome (PCS) score may improve comparison in the course and classification of affected patients. A pr…
View article: Data from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out
Data from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out Open
Multiple genes and their variants that lend susceptibility to many diseases will play a major role in clinical routine. Genetics-based cost reduction strategies in diagnostic processes are important in the setting of multiple susceptibilit…
View article: Supplementary Table 2 from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out
Supplementary Table 2 from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out Open
Supplementary Table 2 from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out
View article: Data from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out
Data from Clinical Predictors for Germline Mutations in Head and Neck Paraganglioma Patients: Cost Reduction Strategy in Genetic Diagnostic Process as Fall-Out Open
Multiple genes and their variants that lend susceptibility to many diseases will play a major role in clinical routine. Genetics-based cost reduction strategies in diagnostic processes are important in the setting of multiple susceptibilit…