Martin Dawes
YOU?
Author Swipe
View article: Late-stage anterior cruciate ligament reconstruction rehabilitation in the United Kingdom: an online survey of National Health Service physiotherapists
Late-stage anterior cruciate ligament reconstruction rehabilitation in the United Kingdom: an online survey of National Health Service physiotherapists Open
View article: Clinical pharmacogenetics: A feasibility study of pharmacy students using a clinical decision support system during their didactic training
Clinical pharmacogenetics: A feasibility study of pharmacy students using a clinical decision support system during their didactic training Open
Background: Pharmacogenetic testing in clinical practice is feasible and cost-effective, and positively impacts healthcare quality and costs. Integrating pharmacogenetics into the pharmacy setting has shown promise in improving medication …
View article: The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models
The neurological pathology of peroxisomal ACBD5 deficiency – lessons from patients and mouse models Open
The absence or dysfunction of the peroxisomal membrane protein Acyl-CoA Binding Domain-Containing Protein 5 (ACBD5) is the cause of the most recently discovered peroxisomal disorder “Retinal Dystrophy with Leukodystrophy” (RDLKD). ACBD5 is…
View article: Are Canadian Clinical Practice Guidelines Accounting for Adults With Multiple Chronic Diseases? A Systematic Review
Are Canadian Clinical Practice Guidelines Accounting for Adults With Multiple Chronic Diseases? A Systematic Review Open
Rationale Recommendations that are equipped with essential and adequate information promote adherence and support evidence‐informed decision‐making, which are crucial attributes of patient‐centered care when caring for patients with multip…
View article: Preventive Lipid-Lowering Therapy and Interactions With Health Care in Patients Who Develop Premature Coronary Artery Disease
Preventive Lipid-Lowering Therapy and Interactions With Health Care in Patients Who Develop Premature Coronary Artery Disease Open
Prior to presenting with premature CAD, most patients had medical encounters, but few received LLT, demonstrating a substantial gap in prevention.
View article: Optimising physiotherapy for people with lateral elbow tendinopathy – Results of a mixed-methods pilot and feasibility randomised controlled trial (OPTimisE)
Optimising physiotherapy for people with lateral elbow tendinopathy – Results of a mixed-methods pilot and feasibility randomised controlled trial (OPTimisE) Open
It is methodologically feasible to conduct a fully powered RCT comparing the clinical and cost-effectiveness of the OPTimisE intervention versus usual physiotherapy treatment. Considering the similar improvements observed in both groups, c…
View article: Home Blood Pressure Telemonitoring Technology for Patients With Asymptomatic Elevated Blood Pressure Discharged From the Emergency Department: Pilot Study
Home Blood Pressure Telemonitoring Technology for Patients With Asymptomatic Elevated Blood Pressure Discharged From the Emergency Department: Pilot Study Open
Background Hypertension affects 1 in 5 Canadians and is the leading cause of morbidity and mortality globally. Hypertension control is declining due to multiple factors including lack of access to primary care. Consequently, patients with …
View article: Home Blood Pressure Telemonitoring Technology for Patients With Asymptomatic Elevated Blood Pressure Discharged From the Emergency Department: Pilot Study (Preprint)
Home Blood Pressure Telemonitoring Technology for Patients With Asymptomatic Elevated Blood Pressure Discharged From the Emergency Department: Pilot Study (Preprint) Open
BACKGROUND Hypertension affects 1 in 5 Canadians and is the leading cause of morbidity and mortality globally. Hypertension control is declining due to multiple factors including lack of access to primary care. Consequently, patients with…
View article: Improving prescribing: a feasibility study of pharmacogenetic testing with clinical decision support in primary healthcare in Singapore
Improving prescribing: a feasibility study of pharmacogenetic testing with clinical decision support in primary healthcare in Singapore Open
Background The study of genetic variation as a factor influencing drug safety, efficacy, and effectiveness has brought about significant breakthroughs in understanding the clinical application of gene–drug interactions to better manage dru…
View article: Adaptations to Opioid Use Disorder Care During the COVID-19 Pandemic: A National Survey of Prescribers.
Adaptations to Opioid Use Disorder Care During the COVID-19 Pandemic: A National Survey of Prescribers. Open
Surveyed prescribers widely used virtual visits to provide MOUD with overall positive experiences. Future studies should evaluate the impact of virtual visits on MOUD access and retention and clinical outcomes.
View article: Feasibility of using pharmacogenetic testing with clinical decision support system in private GP clinics in singapore
Feasibility of using pharmacogenetic testing with clinical decision support system in private GP clinics in singapore Open
Primary care provides patients with immediate care at the first line of treatment. There are about 1,700 private general practitioner (GP) clinics providing 80% of the primary care services in Singapore. These GPs prescribe medications bas…
View article: RetINal Toxicity And HydroxyChloroquine Therapy (INTACT): protocol for a prospective population-based cohort study
RetINal Toxicity And HydroxyChloroquine Therapy (INTACT): protocol for a prospective population-based cohort study Open
Purpose Hydroxychloroquine (HCQ) is an important medication for patients with systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other rheumatic diseases. Although it is well-tolerated and cost-effective, the risk of HCQ ret…
View article: Pharmacogenetics Implementation in Primary Care
Pharmacogenetics Implementation in Primary Care Open
Pharmacogenetics is being considered as a pre-emptive test for the National Health Service in the United Kingdom. Primary care is a key clinical service for the use of this technology due to the large number of prescriptions prescribed in …
View article: Consider patient risk factors for melanoma when prescribing antihypertensives
Consider patient risk factors for melanoma when prescribing antihypertensives Open
Drucker and colleagues provide a great paper[1][1] that raises questions about antihypertensive medications and adverse effects. The adjusted hazard ratio for melanoma with thiazide exposure is quite high at 1.34 (95% confidence interval 1…
View article: Table of Contents
Table of Contents Open
View article: Determining the communicable period of SARS-CoV-2: A rapid review of the literature, March to September 2020
Determining the communicable period of SARS-CoV-2: A rapid review of the literature, March to September 2020 Open
Introduction Standard testing for infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is based on RT-PCR tests, but detection of viral genetic material alone does not indicate ongoing infectious potential. The abili…
View article: Vancouver Coastal Health informed COVID-19 response by applying rapid review methodology: reply to Tricco
Vancouver Coastal Health informed COVID-19 response by applying rapid review methodology: reply to Tricco Open
View article: The challenges of measuring blood pressure during COVID-19
The challenges of measuring blood pressure during COVID-19 Open
Coronavirus disease 2019 (COVID-19) has altered the availability of face-to-face care in family practice. The negative effect on routine care for chronic disease management is an ongoing challenge. The purpose of this article is to describ…
View article: Determining the period of communicability of SARS-CoV-2: A rapid review of the literature
Determining the period of communicability of SARS-CoV-2: A rapid review of the literature Open
Introduction How long individuals may transmit virus after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear. Understanding the communicability period of SARS-CoV-2 is important to inform the period of …
View article: P364 Efficacy of having an activity coordinator in an adult cystic fibrosis ward
P364 Efficacy of having an activity coordinator in an adult cystic fibrosis ward Open
View article: The implementation of pharmacogenomics into UK general practice: a qualitative study exploring barriers, challenges and opportunities
The implementation of pharmacogenomics into UK general practice: a qualitative study exploring barriers, challenges and opportunities Open
View article: Re: Pharmacogenetic Testing Options Relevant to Psychiatry in Canada
Re: Pharmacogenetic Testing Options Relevant to Psychiatry in Canada Open
View article: Trends in end digit preference for blood pressure and associations with cardiovascular outcomes in Canadian and UK primary care: a retrospective observational study
Trends in end digit preference for blood pressure and associations with cardiovascular outcomes in Canadian and UK primary care: a retrospective observational study Open
Objectives To study systematic errors in recording blood pressure (BP) as measured by end digit preference (EDP); to determine associations between EDP, uptake of Automated Office BP (AOBP) machines and cardiovascular outcomes. Design Retr…
View article: The Importance of Relevance: Willingness to Share eHealth Data for Family Medicine Research
The Importance of Relevance: Willingness to Share eHealth Data for Family Medicine Research Open
Objective: To determine the proportion of family medicine patients unwilling to allow their eHealth data to be used for research purposes, and evaluate how patient characteristics and the relevance of research impact that decision. …
View article: Older Adults' Sedentary Behavior and Physical Activity After Hip Fracture: Results From an Outpatient Rehabilitation Randomized Controlled Trial
Older Adults' Sedentary Behavior and Physical Activity After Hip Fracture: Results From an Outpatient Rehabilitation Randomized Controlled Trial Open
Background and Purpose: Prolonged sedentary time and limited physical activity can result in deleterious effects on health and mobility, especially for older adults with fall-related hip fracture. Therefore, the purpose of this study was t…
View article: Randomized Controlled Trial of E-Counseling for Hypertension
Randomized Controlled Trial of E-Counseling for Hypertension Open
Background: The efficacy of internet-based interventions to improve hypertension management is not established. We evaluated the therapeutic benefit of e-counseling by adapting best evidence guidelines for behavioral counseling. Methods an…
View article: Evaluation of buccal swabs for pharmacogenetics
Evaluation of buccal swabs for pharmacogenetics Open
View article: Aromatase inhibitors are associated with a higher fracture risk than tamoxifen: a systematic review and meta-analysis
Aromatase inhibitors are associated with a higher fracture risk than tamoxifen: a systematic review and meta-analysis Open
Background: In this paper, our aim was to systematically evaluate published evidence of bone fracture risk associated with tamoxifen and aromatase inhibitors in women aged 65 and under, and diagnosed with nonmetastatic breast cancer. Metho…
View article: How do family physicians measure blood pressure in routine clinical practice? National survey of Canadian family physicians.
How do family physicians measure blood pressure in routine clinical practice? National survey of Canadian family physicians. Open
Canadian family physicians exhibit overall high use of electronic devices for BP measurement, However, more efforts are needed to encourage practitioners to follow current Canadian guidelines, which advocate the use of AOBP measurement for…
View article: How the ‘omics’ revolution can change primary care
How the ‘omics’ revolution can change primary care Open