Martin Horváth
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View article: The Impact of SGLT-2 Inhibitors on Hydroxyl Radical Markers and Diabetic Neuropathy: A Short-Term Clinical Study
The Impact of SGLT-2 Inhibitors on Hydroxyl Radical Markers and Diabetic Neuropathy: A Short-Term Clinical Study Open
Beyond their metabolic effect, sodium–glucose cotransporter-2 (SGLT-2) inhibitors reduce the risk of heart failure and have cardiovascular and nephroprotective effects, yet their exact mechanism of action remains unclear. This prospective …
View article: Hydroxyl Free Radical Associated Effects of SGLT-2 Inhibitors in Type 2 Diabetes
Hydroxyl Free Radical Associated Effects of SGLT-2 Inhibitors in Type 2 Diabetes Open
Beyond their metabolic effect, SGLT-2 inhibitors reduce the risk of heart failure and have cardiovascular and nephroprotective effects, yet their exact mechanism of action remains unclear. This prospective study included 40 patients with t…
View article: Erratum. Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease. Diabetes Care 2023;46:2015–2023
Erratum. Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease. Diabetes Care 2023;46:2015–2023 Open
In the abstract of the article cited above, the clinical trial number for DISCHARGE (NCT02400229) was inadvertently omitted. The abstract has been revised to include the ClinicalTrials.gov identification. The editors apologize for the erro…
View article: Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial
Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial Open
Background Recent trials support the role of cardiac CT in the evaluation of symptomatic patients suspected of having coronary artery disease (CAD); however, body mass index (BMI) has been reported to negatively impact CT image quality. Pu…
View article: Terápiarefrakter hipomagneziémia rendezése SGLT-2-gátló-terápiával 2-es típusú cukorbetegünknél : esetbemutatás
Terápiarefrakter hipomagneziémia rendezése SGLT-2-gátló-terápiával 2-es típusú cukorbetegünknél : esetbemutatás Open
A 80 éves kettes típusú diabetes mellitus miatt kezelt férfi beteget az elmúlt években számos alkalommal hospitalizáltuk nagy mennyiségű, per os pótlás ellenére parenterális pótlást is igénylő hipomagneziémia miatt. A T2DM miatt eszkaláció…
View article: Increased cardiovascular mortality in patients with mechanically expandable transcatheter aortic valve and without permanent pacemaker
Increased cardiovascular mortality in patients with mechanically expandable transcatheter aortic valve and without permanent pacemaker Open
Introduction Use of the mechanically expandable transcatheter aortic valve (MEV) has been recently linked to increased risks of valve dysfunction and cardiovascular mortality. The risk of developing conduction disturbance with the MEV valv…
View article: Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease
Computed Tomography Versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease Open
OBJECTIVE To compare cardiac computed tomography (CT) with invasive coronary angiography (ICA) as the initial strategy in patients with diabetes and stable chest pain. RESEARCH DESIGN AND METHODS This prespecified analysis of the multicent…
View article: CT versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease
CT versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease Open
OBJECTIVESTo compare cardiac CT with invasive coronary angiography (ICA) as the initial strategy in patients with diabetes and stable chest pain.RESEARCH DESIGN AND METHODS This was a prespecified analysis of the multicenter DISCHARGE tria…
View article: CT versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease
CT versus Invasive Coronary Angiography in Patients With Diabetes and Suspected Coronary Artery Disease Open
OBJECTIVESTo compare cardiac CT with invasive coronary angiography (ICA) as the initial strategy in patients with diabetes and stable chest pain.RESEARCH DESIGN AND METHODS This was a prespecified analysis of the multicenter DISCHARGE tria…
View article: Increased cardiovascular mortality in patients with mechanically expandable transcatheter aortic valve and without permanent pacemaker
Increased cardiovascular mortality in patients with mechanically expandable transcatheter aortic valve and without permanent pacemaker Open
Introduction Use of the mechanically expandable transcatheter aortic valve (MEV) has been recently linked to increased risks of valve dysfunction and cardiovascular mortality. The risk of developing conduction disturbance with the MEV valv…
View article: Comparison of 30-Day Outcomes after Carotid Artery Stenting in Patients with Near-Occlusion and Severe Stenosis: A Propensity Score Matching Analysis
Comparison of 30-Day Outcomes after Carotid Artery Stenting in Patients with Near-Occlusion and Severe Stenosis: A Propensity Score Matching Analysis Open
Carotid stent placement in patients with ICA near-occlusion was not associated with an increased 30-day risk of stroke or death compared with severe stenosis. Survival up to 10 years after carotid artery stenting was similar in both groups.
View article: Mid-term outcomes of patients with Lotus and Evolut transcatheter valves
Mid-term outcomes of patients with Lotus and Evolut transcatheter valves Open
The results of our study suggest that higher cardiovascular mortality rates during mid-term follow-up were associated with Lotus compared with Evolut valves. Higher AVGm in the Lotus valves suggests the possibility of accelerated prosthesi…
View article: Long-term changes after carotid stenting assessed by intravascular ultrasound and near-infrared spectroscopy
Long-term changes after carotid stenting assessed by intravascular ultrasound and near-infrared spectroscopy Open
The trial is registered under clinicaltrials.gov NCT03141580.
View article: Long-term survival of carotid stenting patients with regard to single- or double-vessel carotid artery disease: a propensity score matching analysis
Long-term survival of carotid stenting patients with regard to single- or double-vessel carotid artery disease: a propensity score matching analysis Open
Introduction There is lack of long-term data outside of controlled clinical trials in carotid artery stenting (CAS). In this study, we compared the short-term outcome, long-term survival, and rate of re-interventions for restenosis in pati…
View article: Carotid artery plaque composition and distribution: near-infrared spectroscopy and intravascular ultrasound analysis
Carotid artery plaque composition and distribution: near-infrared spectroscopy and intravascular ultrasound analysis Open
Most atherosclerotic plaques (APs) form in typical predilection areas of low endothelial shear stress (ESS). On the contrary, previous data hinted that plaques rupture in their proximal parts where accelerated blood flow causes high ESS. I…
View article: MicroRNA-331 and microRNA-151-3p as biomarkers in patients with ST-segment elevation myocardial infarction
MicroRNA-331 and microRNA-151-3p as biomarkers in patients with ST-segment elevation myocardial infarction Open
We sought to analyse plasma levels of peripheral blood microRNAs (miRs) as biomarkers of ST-segment-elevation myocardial infarction (STEMI) due to type-1 myocardial infarction as a model situation of vulnerable plaque (VP) rupture. Samples…
View article: High-grade patent foramen ovale is a risk factor of unprovoked decompression sickness in recreational divers
High-grade patent foramen ovale is a risk factor of unprovoked decompression sickness in recreational divers Open
View article: P5206Near-infrared spectroscopy analysis of the carotid artery plaque composition based on the distribution of shear stress
P5206Near-infrared spectroscopy analysis of the carotid artery plaque composition based on the distribution of shear stress Open
View article: P5195Near-infrared spectroscopic assessment of carotid plaque in diabetic versus non-diabetic patients undergoing carotid stenting
P5195Near-infrared spectroscopic assessment of carotid plaque in diabetic versus non-diabetic patients undergoing carotid stenting Open
Purpose: We aimed to compare the effects of BPA on hemodynamics between patients with peripheral-type CTEPH and those with central-type CTPEH who were judged as inoperable for several reasons.Method: Out of 16 CTEPH patients, 60 BPA sessio…
View article: Inferior sinus venosus and two ostium secundum atrial septal defects is possible to treat with three occludersth three occluders
Inferior sinus venosus and two ostium secundum atrial septal defects is possible to treat with three occludersth three occluders Open
A 73-year-old woman known to have multiple atrial septal defects (mASD) since 2006 rejected cardiac surgery and was referred to our department with signs of right heart failure. Echocardiography demonstrated one defect located in the infer…
View article: Catheter-based endovenous laser ablation of saphenous veins in the treatment of symptomatic venous reflux: Early results
Catheter-based endovenous laser ablation of saphenous veins in the treatment of symptomatic venous reflux: Early results Open
Úvod: Katetrizační endovenózní laserová ablace (EVLA) je běžně užívaná alternativa chirurgické léčby varixů dolních končetin a postupně se stává metodou volby. V této observační studii jsme si kladli za cíl prokázat, zda je tato metoda bez…
View article: Evaluation of Cerebrovascular Reserve in Patients Undergoing Carotid Artery Stenting and Its Usefulness in Predicting Significant Hemodynamic Changes During Temporary Carotid Occlusion
Evaluation of Cerebrovascular Reserve in Patients Undergoing Carotid Artery Stenting and Its Usefulness in Predicting Significant Hemodynamic Changes During Temporary Carotid Occlusion Open
We investigated the usefulness of cerebrovascular reserve (CVR) testing to predict severe hemodynamic changes during proximally protected carotid artery stenting. Of 90 patients referred, 63 eligible underwent complete evaluation of the ex…
View article: The role of near-infrared spectroscopy in the detection of vulnerable atherosclerotic plaques
The role of near-infrared spectroscopy in the detection of vulnerable atherosclerotic plaques Open
Coronary artery disease is the leading cause of mortality worldwide. Most acute coronary syndromes are caused by a rupture of a vulnerable atherosclerotic plaque which can be characterized by a lipid-rich necrotic core with an overlying th…
View article: Impact of coexisting multivessel coronary artery disease on short-term outcomes and long-term survival of patients treated with carotid stenting
Impact of coexisting multivessel coronary artery disease on short-term outcomes and long-term survival of patients treated with carotid stenting Open
These results suggest that patients with MVD combined with carotid artery disease are probably not at higher risk of early post-CAS adverse clinical events, but they have significantly worse long-term survival rates.
View article: First-in-man near-infrared spectroscopy proof of lipid-core embolization during carotid artery stenting
First-in-man near-infrared spectroscopy proof of lipid-core embolization during carotid artery stenting Open
Intravascular near-infrared spectroscopy (NIRS), which has been used in over 5,000 patients to identify the lipid-core plaques (LCP) that cause coronary events, may also assist in the characterization of the carotid atherosclerotic lesions…
View article: Intravascular Near-Infrared Spectroscopy: A Possible Tool for Optimizing the Management of Carotid Artery Disease
Intravascular Near-Infrared Spectroscopy: A Possible Tool for Optimizing the Management of Carotid Artery Disease Open
Stroke is the second most common cause of morbidity and mortality in the Western nations. It is estimated that approximately one-fifth of all strokes or transient ischemic attacks are caused by carotid artery disease. Thus, treatment of ca…
View article: Predicting Hemodynamic Changes of Cerebral Blood Flow during Temporal Carotid Occlusion: A Review of Current Knowledge with Implication for Carotid Artery Stenting
Predicting Hemodynamic Changes of Cerebral Blood Flow during Temporal Carotid Occlusion: A Review of Current Knowledge with Implication for Carotid Artery Stenting Open
Carotid artery disease (CAD) plays an important role in the stroke development and its prevalence increases with aging of the population. Its wide variability of clinical manifestation ranges from incidental asymptomatic finding to devasta…