Jahn M. Nesland
YOU?
Author Swipe
View article: Supplementary Table 3 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development
Supplementary Table 3 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development Open
Supplementary Table 3 from Differentiation of Human Embryonal Carcinomas In vitro and In vivo Reveals Expression Profiles Relevant to Normal Development
View article: Data from Targeting PBR by Hexaminolevulinate-Mediated Photodynamic Therapy Induces Apoptosis through Translocation of Apoptosis-Inducing Factor in Human Leukemia Cells
Data from Targeting PBR by Hexaminolevulinate-Mediated Photodynamic Therapy Induces Apoptosis through Translocation of Apoptosis-Inducing Factor in Human Leukemia Cells Open
Photodynamic therapy (PDT) with endogenous protoporphyrin IX derived from 5-aminolevulinic acid or its derivatives has been established for treatments of several premalignancies and malignancies; however, the mechanism of the modality is n…
View article: Supplementary Data from Targeting PBR by Hexaminolevulinate-Mediated Photodynamic Therapy Induces Apoptosis through Translocation of Apoptosis-Inducing Factor in Human Leukemia Cells
Supplementary Data from Targeting PBR by Hexaminolevulinate-Mediated Photodynamic Therapy Induces Apoptosis through Translocation of Apoptosis-Inducing Factor in Human Leukemia Cells Open
Supplementary Data from Targeting PBR by Hexaminolevulinate-Mediated Photodynamic Therapy Induces Apoptosis through Translocation of Apoptosis-Inducing Factor in Human Leukemia Cells
View article: Supplementary Table 4 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development
Supplementary Table 4 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development Open
Supplementary Table 4 from Differentiation of Human Embryonal Carcinomas In vitro and In vivo Reveals Expression Profiles Relevant to Normal Development
View article: Supplementary Table 2B from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development
Supplementary Table 2B from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development Open
Supplementary Table 2B from Differentiation of Human Embryonal Carcinomas In vitro and In vivo Reveals Expression Profiles Relevant to Normal Development
View article: Supplementary Table 4 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development
Supplementary Table 4 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development Open
Supplementary Table 4 from Differentiation of Human Embryonal Carcinomas In vitro and In vivo Reveals Expression Profiles Relevant to Normal Development
View article: Supplementary Table 5 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development
Supplementary Table 5 from Differentiation of Human Embryonal Carcinomas <i>In vitro</i> and <i>In vivo</i> Reveals Expression Profiles Relevant to Normal Development Open
Supplementary Table 5 from Differentiation of Human Embryonal Carcinomas In vitro and In vivo Reveals Expression Profiles Relevant to Normal Development
View article: Evaluation of <scp>CHK</scp>1 activation in vulvar squamous cell carcinoma and its potential as a therapeutic target in vitro
Evaluation of <span>CHK</span>1 activation in vulvar squamous cell carcinoma and its potential as a therapeutic target in vitro Open
CHK 1 is an important regulator of the cell cycle and DNA damage response, and its altered expression has been identified in various tumors. Chk1 inhibitors are currently being evaluated as monotherapy and as potentiators of chemotherapy i…
View article: Generation of an oxoglutarate dehydrogenase knockout rat model and the effect of a high-fat diet
Generation of an oxoglutarate dehydrogenase knockout rat model and the effect of a high-fat diet Open
Although abnormal metabolism in metabolic syndrome and tumours has been well described, the relationship between oxoglutarate dehydrogenase (OGDH) and obesity-related diseases is still largely unknown.
View article: MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells
MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells Open
Our earlier study revealed that long-term ethidium bromide application causes mitochondrial DNA depletion in human prostate cancer DU145 cell line (DU145 MtDP ), and this DU145 MtDP subline appears to have expanded CD44 Bright cell populat…
View article: Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells Open
Flavopiridol (FP) is a pan-cyclin dependent kinase inhibitor, which shows strong efficacy in inducing cancer cell apoptosis. Although FP is potent against most cancer cells in vitro , unfortunately it proved less efficacious in clinical tr…
View article: Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells
Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells Open
One of the remarkable features of cancer cells is aerobic glycolysis, a phenomenon known as the "Warburg Effect", in which cells rely preferentially on glycolysis instead of oxidative phosphorylation (OXPHOS) as the main energy source even…
View article: Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features Open
Present: Due to incorrect labeling on the part of the authors, it was discovered that a different set of cell lines was used than those initially published.The authors confirmed that all the research data presented in this paper were based…
View article: Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers
Pyruvate dehydrogenase expression is negatively associated with cell stemness and worse clinical outcome in prostate cancers Open
Cells generate adenosine-5'-triphosphate (ATP), the major currency for energy-consuming reactions, through mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis. One of the remarkable features of cancer cells is aerobic glycolysi…
View article: Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype <i>in vitro</i> and malignant features in esophageal squamous cell carcinomas
Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype <i>in vitro</i> and malignant features in esophageal squamous cell carcinomas Open
Aerobic glycolysis is one of the emerging hallmarks of cancer cells. In this study, we investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with MPC blocker UK5099 and the metabolic alteration as well as aggr…
View article: Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses
Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses Open
Pyruvate plays a critical role in the mitochondrial tricarboxylic acid (TCA) cycle, and it is the center product for the synthesis of amino acids, carbohydrates and fatty acids. Pyruvate transported across the inner mitochondrial membrane …
View article: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features Open
Reducing mtDNA content was considered as a critical step in the metabolism restructuring for cell stemness restoration and further neoplastic development. However, the connections between mtDNA depletion and metabolism reprograming-based c…
View article: Prognostic and clinicopathological significance of Cacna2d1 expression in epithelial ovarian cancers: a retrospective study.
Prognostic and clinicopathological significance of Cacna2d1 expression in epithelial ovarian cancers: a retrospective study. Open
Ovarian cancer is the most lethal gynecologic malignancy, in which cancer stem cells (CSC) have been reported to be the driving force of relapse and therapy-resistance. It is therefore important to explore CSC markers in ovarian cancer. Th…